BG103190A - Substituted pyrimidine derivatives and their pharmaceutical application - Google Patents

Substituted pyrimidine derivatives and their pharmaceutical application

Info

Publication number
BG103190A
BG103190A BG103190A BG10319099A BG103190A BG 103190 A BG103190 A BG 103190A BG 103190 A BG103190 A BG 103190A BG 10319099 A BG10319099 A BG 10319099A BG 103190 A BG103190 A BG 103190A
Authority
BG
Bulgaria
Prior art keywords
pyrimidine derivatives
substituted pyrimidine
pharmaceutical application
relates
heterocyclic derivatives
Prior art date
Application number
BG103190A
Other languages
Bulgarian (bg)
English (en)
Inventor
George Brown
Nicholas Newcombe
Elaine Stokes
David Waterson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9617060.0A external-priority patent/GB9617060D0/en
Priority claimed from GBGB9703027.4A external-priority patent/GB9703027D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BG103190A publication Critical patent/BG103190A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
BG103190A 1996-08-14 1999-02-22 Substituted pyrimidine derivatives and their pharmaceutical application BG103190A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9617060.0A GB9617060D0 (en) 1996-08-14 1996-08-14 Chemical compounds
GBGB9703027.4A GB9703027D0 (en) 1997-02-14 1997-02-14 Chemical compounds
PCT/GB1997/002029 WO1998006705A1 (en) 1996-08-14 1997-07-25 Substituted pyrimidine derivatives and their pharmaceutical use

Publications (1)

Publication Number Publication Date
BG103190A true BG103190A (en) 1999-11-30

Family

ID=26309870

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103190A BG103190A (en) 1996-08-14 1999-02-22 Substituted pyrimidine derivatives and their pharmaceutical application

Country Status (18)

Country Link
US (1) US6093718A (ja)
EP (1) EP0925286B1 (ja)
JP (1) JP2000516602A (ja)
KR (1) KR20000029984A (ja)
CN (1) CN1228087A (ja)
AT (1) ATE230399T1 (ja)
AU (1) AU3701797A (ja)
BG (1) BG103190A (ja)
BR (1) BR9711135A (ja)
CA (1) CA2260872A1 (ja)
CZ (1) CZ45699A3 (ja)
DE (1) DE69718177T2 (ja)
IL (1) IL128428A0 (ja)
NO (1) NO990663L (ja)
PL (1) PL331599A1 (ja)
SK (1) SK18499A3 (ja)
TR (1) TR199900303T2 (ja)
WO (1) WO1998006705A1 (ja)

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Also Published As

Publication number Publication date
CA2260872A1 (en) 1998-02-19
BR9711135A (pt) 1999-08-17
NO990663L (no) 1999-04-12
AU3701797A (en) 1998-03-06
CN1228087A (zh) 1999-09-08
NO990663D0 (no) 1999-02-12
DE69718177D1 (de) 2003-02-06
KR20000029984A (ko) 2000-05-25
ATE230399T1 (de) 2003-01-15
IL128428A0 (en) 2000-01-31
PL331599A1 (en) 1999-08-02
EP0925286A1 (en) 1999-06-30
JP2000516602A (ja) 2000-12-12
EP0925286B1 (en) 2003-01-02
US6093718A (en) 2000-07-25
TR199900303T2 (xx) 1999-06-21
SK18499A3 (en) 1999-07-12
WO1998006705A1 (en) 1998-02-19
CZ45699A3 (cs) 1999-05-12
DE69718177T2 (de) 2003-10-23

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