BG103112A - Substituted triazolo-pyuridazin derivatives as ligands for gaba receptors - Google Patents

Substituted triazolo-pyuridazin derivatives as ligands for gaba receptors

Info

Publication number
BG103112A
BG103112A BG103112A BG10311299A BG103112A BG 103112 A BG103112 A BG 103112A BG 103112 A BG103112 A BG 103112A BG 10311299 A BG10311299 A BG 10311299A BG 103112 A BG103112 A BG 103112A
Authority
BG
Bulgaria
Prior art keywords
ligands
derivatives
pyuridazin
substituted
gaba receptors
Prior art date
Application number
BG103112A
Other languages
Bulgarian (bg)
English (en)
Inventor
Howard BROUGHTON
William Carling
Pineiro Jose Luis Castro
Alexander GUIBLIN
Andrew Madin
Kevin Moore
Michael Russell
Leslie STREET
Original Assignee
Merck Sharp & Dohme Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9615645.0A external-priority patent/GB9615645D0/en
Priority claimed from GBGB9625397.6A external-priority patent/GB9625397D0/en
Priority claimed from GBGB9714420.8A external-priority patent/GB9714420D0/en
Application filed by Merck Sharp & Dohme Limited filed Critical Merck Sharp & Dohme Limited
Publication of BG103112A publication Critical patent/BG103112A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG103112A 1996-07-25 1999-01-25 Substituted triazolo-pyuridazin derivatives as ligands for gaba receptors BG103112A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9615645.0A GB9615645D0 (en) 1996-07-25 1996-07-25 Therapeutic agents
GBGB9625397.6A GB9625397D0 (en) 1996-12-06 1996-12-06 Therapeutic agents
GBGB9714420.8A GB9714420D0 (en) 1997-07-09 1997-07-09 Therapeutic agents
PCT/GB1997/001946 WO1998004559A2 (en) 1996-07-25 1997-07-17 Substituted triazolo-pyridazine derivatives as ligands for gaba receptors

Publications (1)

Publication Number Publication Date
BG103112A true BG103112A (en) 1999-09-30

Family

ID=27268403

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103112A BG103112A (en) 1996-07-25 1999-01-25 Substituted triazolo-pyuridazin derivatives as ligands for gaba receptors

Country Status (24)

Country Link
US (1) US6255305B1 (de)
EP (1) EP0915875B1 (de)
JP (1) JP4216905B2 (de)
KR (1) KR20000029548A (de)
CN (1) CN1251589A (de)
AT (1) ATE236904T1 (de)
AU (1) AU723098B2 (de)
BG (1) BG103112A (de)
BR (1) BR9710729A (de)
CZ (1) CZ18199A3 (de)
DE (1) DE69720732T2 (de)
EA (1) EA002436B1 (de)
EE (1) EE9900027A (de)
ES (1) ES2194205T3 (de)
HU (1) HUP0600527A2 (de)
IL (1) IL127911A0 (de)
IS (1) IS4949A (de)
NO (1) NO990304L (de)
NZ (1) NZ333768A (de)
PL (1) PL331072A1 (de)
SK (1) SK9399A3 (de)
TR (1) TR199900047T2 (de)
WO (1) WO1998004559A2 (de)
YU (1) YU2899A (de)

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Also Published As

Publication number Publication date
TR199900047T2 (xx) 1999-03-22
EP0915875B1 (de) 2003-04-09
NO990304L (no) 1999-03-25
DE69720732T2 (de) 2004-01-29
SK9399A3 (en) 2000-04-10
EA002436B1 (ru) 2002-04-25
HUP0600527A2 (en) 2006-11-28
AU3553997A (en) 1998-02-20
IL127911A0 (en) 1999-11-30
JP4216905B2 (ja) 2009-01-28
EE9900027A (et) 1999-08-16
BR9710729A (pt) 1999-08-17
EP0915875A2 (de) 1999-05-19
DE69720732D1 (de) 2003-05-15
CN1251589A (zh) 2000-04-26
NZ333768A (en) 2000-09-29
JP2002514169A (ja) 2002-05-14
NO990304D0 (no) 1999-01-22
YU2899A (sh) 2000-03-21
US6255305B1 (en) 2001-07-03
IS4949A (is) 1999-01-19
ES2194205T3 (es) 2003-11-16
AU723098B2 (en) 2000-08-17
ATE236904T1 (de) 2003-04-15
WO1998004559A2 (en) 1998-02-05
CZ18199A3 (cs) 1999-06-16
EA199900164A1 (ru) 2000-04-24
KR20000029548A (ko) 2000-05-25
PL331072A1 (en) 1999-06-21

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