ZA9710265B - Substituted Tetrahydro-1,3,5-Triazin-2[1H]-thiones as anti-atherosclerotic agents. - Google Patents

Substituted Tetrahydro-1,3,5-Triazin-2[1H]-thiones as anti-atherosclerotic agents.

Info

Publication number
ZA9710265B
ZA9710265B ZA9710265A ZA9710265A ZA9710265B ZA 9710265 B ZA9710265 B ZA 9710265B ZA 9710265 A ZA9710265 A ZA 9710265A ZA 9710265 A ZA9710265 A ZA 9710265A ZA 9710265 B ZA9710265 B ZA 9710265B
Authority
ZA
South Africa
Prior art keywords
thiones
triazin
atherosclerotic agents
substituted tetrahydro
tetrahydro
Prior art date
Application number
ZA9710265A
Inventor
Kevin A Memoli
Donald P Strike
Amedeo A Failli
Robert J Steffan
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of ZA9710265B publication Critical patent/ZA9710265B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/08—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9710265A 1996-11-14 1997-11-13 Substituted Tetrahydro-1,3,5-Triazin-2[1H]-thiones as anti-atherosclerotic agents. ZA9710265B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74887696A 1996-11-14 1996-11-14

Publications (1)

Publication Number Publication Date
ZA9710265B true ZA9710265B (en) 1999-08-13

Family

ID=25011313

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9710265A ZA9710265B (en) 1996-11-14 1997-11-13 Substituted Tetrahydro-1,3,5-Triazin-2[1H]-thiones as anti-atherosclerotic agents.

Country Status (7)

Country Link
EP (1) EP0938480A1 (en)
JP (1) JP2001503769A (en)
AR (1) AR010068A1 (en)
AU (1) AU5170698A (en)
CA (1) CA2271728A1 (en)
WO (1) WO1998021190A1 (en)
ZA (1) ZA9710265B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001294910A1 (en) 2000-10-02 2002-04-15 American Home Products Corporation 3-thioxo-(1,2,4)-oxadiazinan-5-one and their use as anti-antherosclerotic agents
CA2454059A1 (en) * 2001-07-19 2003-01-30 Cv Therapeutics, Inc. Substituted piperazine compounds and their use as fatty acid oxidation inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK236878A (en) * 1977-07-22 1979-01-23 Pfizer Tetrahydro-s-triazine-2 (1H) -thiones
HUT62558A (en) * 1991-07-01 1993-05-28 Sandoz Ag Process for producing n-phenylthiourea derivaties and pharmaceutical compositions comprising same
US5554607A (en) * 1995-11-28 1996-09-10 American Home Products Corporation Use of 2-thioxo-imidazolin-4-one derivatives in the treatment of atherosclerosis
AU707732B2 (en) * 1996-03-07 1999-07-15 American Home Products Corporation 2-thioxotetrahydropyrimidin-4-one derivatives

Also Published As

Publication number Publication date
AR010068A1 (en) 2000-05-17
WO1998021190A1 (en) 1998-05-22
JP2001503769A (en) 2001-03-21
EP0938480A1 (en) 1999-09-01
AU5170698A (en) 1998-06-03
CA2271728A1 (en) 1998-05-22

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