BG102413A - Скъсени форми на хемокин вета-8 - Google Patents

Скъсени форми на хемокин вета-8 Download PDF

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Publication number
BG102413A
BG102413A BG102413A BG10241398A BG102413A BG 102413 A BG102413 A BG 102413A BG 102413 A BG102413 A BG 102413A BG 10241398 A BG10241398 A BG 10241398A BG 102413 A BG102413 A BG 102413A
Authority
BG
Bulgaria
Prior art keywords
polypeptide
sequence
cells
polypeptides
skr
Prior art date
Application number
BG102413A
Other languages
Bulgarian (bg)
English (en)
Inventor
John White
Edward Appelbaum
SHANNESSY Daniel O'
James FORNWALD
Kevin O'donnell
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of BG102413A publication Critical patent/BG102413A/bg

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/523Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
BG102413A 1995-09-29 1998-04-29 Скъсени форми на хемокин вета-8 BG102413A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US451795P 1995-09-29 1995-09-29
PCT/US1996/015592 WO1997012041A1 (en) 1995-09-29 1996-09-27 SHORT FORMS OF CHEMOKINE β-8

Publications (1)

Publication Number Publication Date
BG102413A true BG102413A (bg) 1999-04-30

Family

ID=21711157

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102413A BG102413A (bg) 1995-09-29 1998-04-29 Скъсени форми на хемокин вета-8

Country Status (16)

Country Link
EP (1) EP0859842A4 (pt)
JP (1) JPH11512610A (pt)
KR (2) KR19990063834A (pt)
CN (2) CN1198186A (pt)
AU (1) AU711573B2 (pt)
BG (1) BG102413A (pt)
BR (1) BR9610671A (pt)
CZ (1) CZ92198A3 (pt)
EA (1) EA199800352A1 (pt)
HU (1) HUP9802699A3 (pt)
NO (1) NO981387L (pt)
NZ (1) NZ320932A (pt)
PL (1) PL326080A1 (pt)
TR (1) TR199800575T1 (pt)
WO (1) WO1997012041A1 (pt)
ZA (1) ZA968204B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6811773B1 (en) 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6001606A (en) * 1994-03-08 1999-12-14 Human Genome Sciences, Inc. Polynucleotides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) and polypeptides encoded thereby
US6451562B1 (en) 1993-12-22 2002-09-17 Human Genome Sciences, Inc. Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
CA2267193A1 (en) * 1996-09-30 1998-04-09 Human Genome Sciences, Inc. Therapeutic compositions and methods for treating disease states with myeloid progenitor inhibitory factor-1 (mpif-1), monocyte colony inhibitory factor (m-cif), and macrophage inhibitory factor-4 (mip-4)
KR19990042713A (ko) * 1997-11-27 1999-06-15 허일섭 사람에서 분리한 c 6 베타-케모카인 lkn-1의 cdna 및 재조합 lkn-1의 제조방법
AU2505601A (en) * 1999-11-15 2001-05-30 Wolf-Georg Forssmann Novel use of hcc-2
US20030215460A1 (en) * 2002-05-07 2003-11-20 Schall Thomas J. Methods and compositions for inducing an immune response

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT735818E (pt) * 1993-12-22 2004-07-30 Human Genome Sciences Inc Proteinas inflamatorias de macrofagos pim-3 pim-4 e pim-1y
AU3134695A (en) * 1995-05-05 1996-11-21 Human Genome Sciences, Inc. Human chemokine beta-8, chemokine beta-1 and macrophage infl ammatory protein-4
DK0871664T3 (da) * 1995-10-24 2004-04-26 Smithkline Beecham Corp Mobilisering af bloddannende stamceller ved anvendelse af en chemokin
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10

Also Published As

Publication number Publication date
CN1405180A (zh) 2003-03-26
AU7379096A (en) 1997-04-17
EP0859842A4 (en) 1999-02-24
AU711573B2 (en) 1999-10-14
NO981387D0 (no) 1998-03-26
NZ320932A (en) 2000-01-28
BR9610671A (pt) 1999-07-06
ZA968204B (en) 1997-04-09
KR19990063834A (ko) 1999-07-26
EA199800352A1 (ru) 1998-12-24
CN1198186A (zh) 1998-11-04
TR199800575T1 (en) 1998-06-22
WO1997012041A1 (en) 1997-04-03
PL326080A1 (en) 1998-08-17
HUP9802699A3 (en) 2000-09-28
KR20030096447A (ko) 2003-12-31
CZ92198A3 (cs) 1998-07-15
HUP9802699A2 (hu) 1999-03-29
EP0859842A1 (en) 1998-08-26
MX9802380A (es) 1998-08-30
NO981387L (no) 1998-05-29
JPH11512610A (ja) 1999-11-02

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