BG100366A - Метод за получаване на заместени 4,6-диамино-5-цианопиримидини - Google Patents

Метод за получаване на заместени 4,6-диамино-5-цианопиримидини

Info

Publication number
BG100366A
BG100366A BG100366A BG10036696A BG100366A BG 100366 A BG100366 A BG 100366A BG 100366 A BG100366 A BG 100366A BG 10036696 A BG10036696 A BG 10036696A BG 100366 A BG100366 A BG 100366A
Authority
BG
Bulgaria
Prior art keywords
alkalimetallic
formula
alkyl
produced
diamino
Prior art date
Application number
BG100366A
Other languages
English (en)
Inventor
Jean-Marie Assersq
Heinz Schwemlein
Jeffrey Perine
Original Assignee
Ciba - Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba - Geigy Ag filed Critical Ciba - Geigy Ag
Publication of BG100366A publication Critical patent/BG100366A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

По метода 2-заместени 4,6-диамино-5-цианопиримидини с формула, в която r1 означава водород, с2-с6-алкил, с2-с6-алкенил или с2-с6-алкинил и r2 е водород, с1-с10-алкил или с3-с6-циклоалкил или r1 и r2 заедно означават радикал,q избран от групата -(сн2)3-, -(сн2)4и -(сн2)5-, се получават, като
BG100366A 1993-07-26 1996-02-19 Метод за получаване на заместени 4,6-диамино-5-цианопиримидини BG100366A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9714193A 1993-07-26 1993-07-26
US21098094A 1994-03-21 1994-03-21
PCT/EP1994/002312 WO1995003282A2 (en) 1993-07-26 1994-07-14 Process for the preparation of substituted 4,6-diamino-5-cyanopyrimidines

Publications (1)

Publication Number Publication Date
BG100366A true BG100366A (bg) 1996-07-31

Family

ID=26792702

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100366A BG100366A (bg) 1993-07-26 1996-02-19 Метод за получаване на заместени 4,6-диамино-5-цианопиримидини

Country Status (15)

Country Link
EP (1) EP0711285A1 (bg)
JP (1) JPH09500632A (bg)
CN (1) CN1128024A (bg)
AU (1) AU7385994A (bg)
BG (1) BG100366A (bg)
BR (1) BR9407024A (bg)
CA (1) CA2166989A1 (bg)
CZ (1) CZ22496A3 (bg)
FI (1) FI960332A (bg)
HU (1) HUT73357A (bg)
IL (1) IL110425A0 (bg)
LV (1) LV11463B (bg)
NO (1) NO960307D0 (bg)
SK (1) SK10396A3 (bg)
WO (1) WO1995003282A2 (bg)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1007516E (pt) * 1997-08-27 2004-11-30 Novartis Ag Polimorfos e hidratos de diciclanilo e sua preparacao
ATE528283T1 (de) 2007-04-19 2011-10-15 Nippon Soda Co Verfahren zur herstellung von n-(2-amino-1,2- dicyanovinyl)imidaten und verfahren zur herstellung von aminoimidazolderivaten
CN102250017A (zh) * 2011-06-15 2011-11-23 扬州天和药业有限公司 地昔尼尔的一种合成方法
CN102399193A (zh) * 2011-12-15 2012-04-04 连云港市亚晖医药化工有限公司 4,6-二氨基-2-环丙胺基-5-腈基嘧啶的制备方法
CN104130197A (zh) * 2014-07-29 2014-11-05 华中农业大学 2,4,6-三氨基-5-氰基嘧啶的化学合成方法
CN104649982B (zh) * 2015-02-26 2016-12-07 齐鲁晟华制药有限公司 一种地昔尼尔的制备方法
CN107056655B (zh) * 2017-01-22 2018-12-04 营口三征新科技化工有限公司 一种1-氨基-1-氰氨基-2,2-二氰乙烯钠盐的制备方法
CN106966922B (zh) * 2017-03-28 2020-10-27 中国科学院大学 一种功能化取代的二氰基乙烯类化合物的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1135913B (de) * 1960-11-08 1962-09-06 Bayer Ag Verfahren zur Herstellung von 2-Methyl-4-amino-5-cyanpyrimidin
US3226424A (en) * 1962-10-03 1965-12-28 Hoffmann La Roche Process for preparing 2-lower alkoxy-1,1-dicyanoethylene and 2-amino-1,1-dicyanoethylene
US4783468A (en) * 1986-04-30 1988-11-08 Ciba-Geigy Corporation Insecticidal 5-pyrimidine carbonitriles

Also Published As

Publication number Publication date
NO960307L (no) 1996-01-25
AU7385994A (en) 1995-02-20
WO1995003282A2 (en) 1995-02-02
BR9407024A (pt) 1996-09-10
JPH09500632A (ja) 1997-01-21
LV11463A (lv) 1996-08-20
FI960332A0 (fi) 1996-01-24
SK10396A3 (en) 1996-09-04
WO1995003282A3 (en) 1995-04-13
HU9503959D0 (en) 1996-03-28
NO960307D0 (no) 1996-01-25
CN1128024A (zh) 1996-07-31
FI960332A (fi) 1996-01-24
IL110425A0 (en) 1994-10-21
HUT73357A (en) 1996-07-29
EP0711285A1 (en) 1996-05-15
CZ22496A3 (en) 1996-04-17
CA2166989A1 (en) 1995-02-02
LV11463B (en) 1996-12-20

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