BE902014A - Nouvelles 13,14,19,20-tetradehydro-carboprostacyclines et procede de preparation. - Google Patents
Nouvelles 13,14,19,20-tetradehydro-carboprostacyclines et procede de preparation.Info
- Publication number
- BE902014A BE902014A BE0/214702A BE214702A BE902014A BE 902014 A BE902014 A BE 902014A BE 0/214702 A BE0/214702 A BE 0/214702A BE 214702 A BE214702 A BE 214702A BE 902014 A BE902014 A BE 902014A
- Authority
- BE
- Belgium
- Prior art keywords
- hydrogen atom
- symbols
- alkyl radical
- compounds
- agents
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical compound [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Composés de formule (I) dans laquelle R représente un atome d'hydrogène ou un radical alkyle en C1-C6; m représente un nombre entier dont la valeur varie de 1 à 5; l'un des symboles R1 et R2 représente un atome d'hydrogène ou un radical alkyle en C1-C6, cependant que l'autre de ces symboles représente le radical hydroxyle; l'un des symboles R3 et R4 représente un atome d'hydrogène, cependant que l'autre de ces symboles représente un atome d'hydrogène ou un radical alkyle en C1-C4, et R5 représente un radical alkyle en C1-C6 ainsi que les sels acceptables en pharmacie humaine ou en pharmacie vétérinaire de ces composés. Les composés de formule (I) possèdent une utilité particulière à titre d'agents d'antithromboagglutination et/ou de thrombodésagglutination, et de plus à titre d'agents vasodilatateurs.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB08407793A GB2156342B (en) | 1984-03-26 | 1984-03-26 | 13,14,19,20-tetradehydro derivatives of carboprostacyclins and process for their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
BE902014A true BE902014A (fr) | 1985-07-16 |
Family
ID=10558690
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/214702A BE902014A (fr) | 1984-03-26 | 1985-03-25 | Nouvelles 13,14,19,20-tetradehydro-carboprostacyclines et procede de preparation. |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS60209545A (fr) |
BE (1) | BE902014A (fr) |
DE (1) | DE3507942A1 (fr) |
GB (1) | GB2156342B (fr) |
IT (1) | IT1183478B (fr) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2038333B (en) * | 1978-01-26 | 1982-10-06 | Erba Farmitalia | 12 -formyl- (20 12)octanor-9-deoxy-9 -methylene pgi derivatives |
-
1984
- 1984-03-26 GB GB08407793A patent/GB2156342B/en not_active Expired
-
1985
- 1985-03-05 IT IT19767/85A patent/IT1183478B/it active
- 1985-03-06 DE DE19853507942 patent/DE3507942A1/de not_active Withdrawn
- 1985-03-22 JP JP60055776A patent/JPS60209545A/ja active Pending
- 1985-03-25 BE BE0/214702A patent/BE902014A/fr not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GB2156342B (en) | 1987-12-23 |
IT8519767A0 (it) | 1985-03-05 |
JPS60209545A (ja) | 1985-10-22 |
GB8407793D0 (en) | 1984-05-02 |
IT1183478B (it) | 1987-10-22 |
GB2156342A (en) | 1985-10-09 |
DE3507942A1 (de) | 1985-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: FARMITALIA CARLO ERBA S.P.A. Effective date: 19910331 |