BE901603A - Isomeres de l'hydroxyvitamine d2. - Google Patents

Isomeres de l'hydroxyvitamine d2.

Info

Publication number
BE901603A
BE901603A BE0/214414A BE214414A BE901603A BE 901603 A BE901603 A BE 901603A BE 0/214414 A BE0/214414 A BE 0/214414A BE 214414 A BE214414 A BE 214414A BE 901603 A BE901603 A BE 901603A
Authority
BE
Belgium
Prior art keywords
vitamin
hydroxyvitamin
isomers
compounds
metabolites
Prior art date
Application number
BE0/214414A
Other languages
English (en)
Inventor
Luca H F De
H K Schnoes
R R Sicinski
Y Tanaka
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of BE901603A publication Critical patent/BE901603A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nouveaux dérivés de la vitamine D, les isomères de la 25-hydroxyvitamine D2 et de la 1 alpha , 25-dihydroxy-vitamine D2(c) qui comprennent une double liaison en position 23,24. Ces composés se distinguent par une activité vitaminoide D mise en évidence par des épreuves de combinaison compétitive. Ces composés sont donc préférés pour remplacer la vitamine D et certains de ces métabolites dans différentes applications connues, de meme que pour le traitement de maladies osseuses curables par la vitamine D.
BE0/214414A 1984-01-30 1985-01-29 Isomeres de l'hydroxyvitamine d2. BE901603A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/575,115 US4505906A (en) 1984-01-30 1984-01-30 Hydroxyvitamin D2 isomers

Publications (1)

Publication Number Publication Date
BE901603A true BE901603A (fr) 1985-05-17

Family

ID=24299018

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214414A BE901603A (fr) 1984-01-30 1985-01-29 Isomeres de l'hydroxyvitamine d2.

Country Status (11)

Country Link
US (1) US4505906A (fr)
JP (1) JPS61501088A (fr)
BE (1) BE901603A (fr)
CH (1) CH668258A5 (fr)
DE (2) DE3490636T1 (fr)
DK (1) DK437485D0 (fr)
FR (1) FR2558829B1 (fr)
GB (1) GB2153829B (fr)
IE (1) IE57935B1 (fr)
NL (1) NL8420327A (fr)
WO (1) WO1985003298A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613594A (en) * 1984-11-16 1986-09-23 Hoffmann-La Roche Inc. Fluorinated vitamin D3 compounds
ZA8923B (en) * 1988-01-20 1989-09-27 Hoffmann La Roche 16-dehydro-vitamin d3-derivatives
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
GB8915770D0 (en) * 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
DE69331409T2 (de) * 1992-06-22 2002-08-29 Bone Care Internat Inc Oral 1alpha-hydroxyprevitamin d
ATE168367T1 (de) * 1994-01-20 1998-08-15 Duphar Int Res Vitamin-d-derivate und verfahren zu deren herstellung
IL118156A (en) * 1995-05-09 2001-08-26 Duphar Int Res Vitamin d compounds, their preparation and pharmaceutical compositions containing them
US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
US6432936B1 (en) 1999-01-20 2002-08-13 Wisconsin Alumni Research Foundation Crystalline 1α-hydroxyvitamin D2 and method of purification thereof
US6479474B2 (en) 1999-07-08 2002-11-12 Wisconsin Alumni Research Foundation Dietary calcium as a supplement to vitamin D compound treatment of multiple sclerosis
WO2004047673A2 (fr) * 2002-11-21 2004-06-10 Novacea, Inc. Traitement des maladies du foie avec des composes actifs de la vitamine d
CN107019795A (zh) * 2009-01-27 2017-08-08 博格有限责任公司 用于减轻与化疗有关的副作用的维生素d3化合物
MX366076B (es) 2009-08-14 2019-06-27 Berg Llc Vitamina d3 y analogos de la misma para tratar alopecia.
NZ714801A (en) 2013-05-29 2021-07-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3585221A (en) * 1969-03-24 1971-06-15 Wisconsin Alumni Res Found 25-hydroxyergocalciferol
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
JPS53147051A (en) * 1977-05-24 1978-12-21 Teijin Ltd 1alpha-hydroxy-24-dehydro-vitamin d3 and its preparation
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same

Also Published As

Publication number Publication date
DE3490636C2 (de) 1995-09-21
JPH0480022B2 (fr) 1992-12-17
GB2153829B (en) 1987-08-12
FR2558829B1 (fr) 1987-01-16
JPS61501088A (ja) 1986-05-29
FR2558829A1 (fr) 1985-08-02
DE3490636T1 (de) 1986-04-03
NL8420327A (nl) 1985-12-02
DK437485A (da) 1985-09-27
GB8502162D0 (en) 1985-02-27
IE57935B1 (en) 1993-05-19
CH668258A5 (de) 1988-12-15
US4505906A (en) 1985-03-19
DK437485D0 (da) 1985-09-27
IE850211L (en) 1985-07-30
GB2153829A (en) 1985-08-29
WO1985003298A1 (fr) 1985-08-01

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: WISCONSIN ALUMNI RESEARCH FOUNDATION

Effective date: 19960131