BE899007A - Nouveaux isoxazoles et procede pour leur preparation - Google Patents

Nouveaux isoxazoles et procede pour leur preparation

Info

Publication number
BE899007A
BE899007A BE1/10966A BE1010966A BE899007A BE 899007 A BE899007 A BE 899007A BE 1/10966 A BE1/10966 A BE 1/10966A BE 1010966 A BE1010966 A BE 1010966A BE 899007 A BE899007 A BE 899007A
Authority
BE
Belgium
Prior art keywords
preparation
isoxazoles
novel
novel isoxazoles
group
Prior art date
Application number
BE1/10966A
Other languages
English (en)
Original Assignee
Richter Gedeon Vegyeszet
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet, Biogal Gyogyszergyar filed Critical Richter Gedeon Vegyeszet
Publication of BE899007A publication Critical patent/BE899007A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Abstract

Procédé de préparation de nouveaux dérivés isoxazoles de formule générale (I) dans laquelle on fait réagir des composés de formules (II) et/ou (IIa) avec une base forte pour obtenir un composé contenant, comme substituants, un groupe nitrile ou un groupe carboxyle. Application pour la préparation de la thiénamycine.
BE1/10966A 1983-02-28 1984-02-27 Nouveaux isoxazoles et procede pour leur preparation BE899007A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU83661A HU189236B (en) 1983-02-28 1983-02-28 Process for producing new type isoxazoles

Publications (1)

Publication Number Publication Date
BE899007A true BE899007A (fr) 1984-08-27

Family

ID=10950718

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/10966A BE899007A (fr) 1983-02-28 1984-02-27 Nouveaux isoxazoles et procede pour leur preparation

Country Status (12)

Country Link
JP (1) JPS59164784A (fr)
BE (1) BE899007A (fr)
CH (1) CH658655A5 (fr)
DE (1) DE3405422A1 (fr)
ES (3) ES8601935A1 (fr)
FR (1) FR2541678A1 (fr)
GB (1) GB2135996B (fr)
HU (1) HU189236B (fr)
IT (1) IT1174498B (fr)
NL (1) NL8400575A (fr)
PT (1) PT78157B (fr)
SE (1) SE8401064L (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366987A (en) * 1991-08-22 1994-11-22 Warner-Lambert Company Isoxazolyl-substituted alkyl amide ACAT inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4163057A (en) * 1977-12-27 1979-07-31 Sandoz, Inc. Isoxazole-4-carboxamides as tranquilizers, sleep-inducers and muscle relaxants

Also Published As

Publication number Publication date
ES544191A0 (es) 1986-01-16
SE8401064L (sv) 1984-08-29
FR2541678A1 (fr) 1984-08-31
IT1174498B (it) 1987-07-01
GB8405001D0 (en) 1984-04-04
ES8604175A1 (es) 1986-01-16
GB2135996A (en) 1984-09-12
ES530121A0 (es) 1985-11-16
PT78157A (de) 1984-03-01
ES8601935A1 (es) 1985-11-16
IT8419806A0 (it) 1984-02-27
CH658655A5 (de) 1986-11-28
HU189236B (en) 1986-06-30
ES8604174A1 (es) 1986-01-16
ES544192A0 (es) 1986-01-16
JPS59164784A (ja) 1984-09-17
NL8400575A (nl) 1984-09-17
GB2135996B (en) 1986-09-10
DE3405422A1 (de) 1984-08-30
SE8401064D0 (sv) 1984-02-27
PT78157B (de) 1986-05-19

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BIOGAL GYOGYSZERGYAR

Effective date: 19890228

Owner name: RICHTER GEDEON VEGYESZETI GYAR R.T.

Effective date: 19890228