BE896403A - Acides 8-cyano-6-7-dihydro-5-methyl-1-oxo-1h,5h-benzo/ij/ quinolizine-2-carboxyliques, leur preparation et leurs utilisations - Google Patents

Acides 8-cyano-6-7-dihydro-5-methyl-1-oxo-1h,5h-benzo/ij/ quinolizine-2-carboxyliques, leur preparation et leurs utilisations

Info

Publication number
BE896403A
BE896403A BE0/210508A BE896403A BE896403A BE 896403 A BE896403 A BE 896403A BE 0/210508 A BE0/210508 A BE 0/210508A BE 896403 A BE896403 A BE 896403A BE 896403 A BE896403 A BE 896403A
Authority
BE
Belgium
Prior art keywords
quinolizine
benzo
dihydro
oxo
cyano
Prior art date
Application number
BE0/210508A
Other languages
English (en)
Inventor
R M Stern
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Publication of BE896403A publication Critical patent/BE896403A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/58—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
BE0/210508A 1981-11-06 1983-04-07 Acides 8-cyano-6-7-dihydro-5-methyl-1-oxo-1h,5h-benzo/ij/ quinolizine-2-carboxyliques, leur preparation et leurs utilisations BE896403A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/318,928 US4380543A (en) 1981-11-06 1981-11-06 Antimicrobial 8-cyano-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acids

Publications (1)

Publication Number Publication Date
BE896403A true BE896403A (fr) 1983-10-07

Family

ID=23240167

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/210508A BE896403A (fr) 1981-11-06 1983-04-07 Acides 8-cyano-6-7-dihydro-5-methyl-1-oxo-1h,5h-benzo/ij/ quinolizine-2-carboxyliques, leur preparation et leurs utilisations

Country Status (9)

Country Link
US (1) US4380543A (fr)
JP (1) JPS59190971A (fr)
BE (1) BE896403A (fr)
CA (2) CA1217493A (fr)
DE (1) DE3312957A1 (fr)
FR (1) FR2544316A1 (fr)
GB (1) GB2136795B (fr)
NL (1) NL8301115A (fr)
SE (1) SE449488B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565872A (en) * 1982-06-07 1986-01-21 Riker Laboratories, Inc. Process for 8-cyano-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acids and intermediates thereof
US4472407A (en) * 1983-03-17 1984-09-18 Riker Laboratories, Inc. Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu
US4898945A (en) * 1986-01-22 1990-02-06 Minnesota Mining And Manufacturing Company Process for 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid
CN111499539B (zh) * 2020-04-20 2022-10-11 南昌大学 一种以芳基羧酸为原料的芳基氰化物合成方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793524A (fr) * 1971-12-30 1973-06-29 Riker Laboratories Inc Acides benzoquinolizine-carboxyliques et leurs derives
JPS584717B2 (ja) * 1977-11-15 1983-01-27 大塚製薬株式会社 ピリド〔３，２，１−ｊｋ〕カルバゾ−ル誘導体
JPS5527204A (en) * 1978-08-16 1980-02-27 Toray Ind Inc Linear polyester film with mat surface
JPS5559121A (en) * 1978-10-30 1980-05-02 Shin Etsu Chem Co Ltd 1-halo-3-decyne compound
JPS5561776A (en) * 1978-11-04 1980-05-09 Nisshin Flour Milling Co Ltd Method of increasing protein content in defatted soybean powder
JPS55106776A (en) * 1979-02-02 1980-08-15 Inoue Mfg Monkey wrench
JPS55131632A (en) * 1979-03-30 1980-10-13 Hitachi Ltd Air conditioner
IT1111918B (it) * 1979-04-10 1986-01-13 Riker Laboratories Inc Medicamento veterinario a base di acidi benzochinolizin carbossilici e loro derivati
DE2949908A1 (de) * 1979-12-12 1981-06-19 Hoechst Ag, 6230 Frankfurt Rieselfaehige sinterpulver mit verbesserten eigenschaften auf basis von tetrafluorethylen-polymeren und verfahren zu deren herstellung
US4341691A (en) * 1980-02-20 1982-07-27 Zimmer, Inc. Low viscosity bone cement
JPS56131631A (en) * 1980-03-21 1981-10-15 Showa Electric Wire & Cable Co Ltd Crosslinked silyl-modified polyolefin film and laminated paper using the same
JPS56135807A (en) * 1980-03-26 1981-10-23 Sumitomo Electric Ind Ltd Optical fiber cable
NO156828C (no) * 1980-11-10 1987-12-02 Otsuka Pharma Co Ltd Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser.
US4400386A (en) * 1981-11-06 1983-08-23 Riker Laboratories, Inc. Antimicrobial derivatives of 8-amino and 8-aminomethyl benzo(ij)quinolizine
US4404207A (en) * 1981-11-06 1983-09-13 Riker Laboratories, Inc. Antimicrobial 8-substituted benzo [IJ]quinolizines

Also Published As

Publication number Publication date
SE449488B (sv) 1987-05-04
SE8301687D0 (sv) 1983-03-28
GB2136795B (en) 1987-03-25
CA1217493A (fr) 1987-02-03
JPS59190971A (ja) 1984-10-29
GB8307351D0 (en) 1983-04-27
US4380543A (en) 1983-04-19
NL8301115A (nl) 1984-10-16
SE8301687L (sv) 1984-09-29
DE3312957A1 (de) 1984-10-11
FR2544316A1 (fr) 1984-10-19
GB2136795A (en) 1984-09-26
CA1226290A (fr) 1987-09-01

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: RIKER LABORATORIES INC.

Effective date: 19870430