BE875089A - Procede de preparation de tetrahydrobenzoxocines et de cishexahydrodibenzopyranones - Google Patents

Procede de preparation de tetrahydrobenzoxocines et de cishexahydrodibenzopyranones

Info

Publication number
BE875089A
BE875089A BE1/9328A BE1009328A BE875089A BE 875089 A BE875089 A BE 875089A BE 1/9328 A BE1/9328 A BE 1/9328A BE 1009328 A BE1009328 A BE 1009328A BE 875089 A BE875089 A BE 875089A
Authority
BE
Belgium
Prior art keywords
tetrahydrobenzoxocins
cishexahydrodibenzopyranones
preparation
Prior art date
Application number
BE1/9328A
Other languages
English (en)
French (fr)
Inventor
C W Ryan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE875089A publication Critical patent/BE875089A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE1/9328A 1978-03-31 1979-03-26 Procede de preparation de tetrahydrobenzoxocines et de cishexahydrodibenzopyranones BE875089A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/892,350 US4171315A (en) 1978-03-31 1978-03-31 Preparation of cis-hexahydrodibenzopyranones

Publications (1)

Publication Number Publication Date
BE875089A true BE875089A (fr) 1979-09-26

Family

ID=25399829

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/9328A BE875089A (fr) 1978-03-31 1979-03-26 Procede de preparation de tetrahydrobenzoxocines et de cishexahydrodibenzopyranones

Country Status (31)

Country Link
US (1) US4171315A (xx)
EP (1) EP0004753B1 (xx)
JP (1) JPS5927350B2 (xx)
AT (1) AT363469B (xx)
AU (1) AU516719B2 (xx)
BE (1) BE875089A (xx)
BG (2) BG32850A3 (xx)
CA (1) CA1132589A (xx)
CH (1) CH638198A5 (xx)
CS (2) CS208493B2 (xx)
DD (1) DD143612A5 (xx)
DE (1) DE2962942D1 (xx)
DK (1) DK132779A (xx)
EG (1) EG13932A (xx)
ES (1) ES479066A1 (xx)
FI (1) FI790981A (xx)
FR (1) FR2421171A1 (xx)
GB (1) GB2017703B (xx)
GR (1) GR71467B (xx)
HU (1) HU179972B (xx)
IE (1) IE48446B1 (xx)
IL (1) IL56944A (xx)
LU (1) LU81086A1 (xx)
MX (1) MX5532E (xx)
NZ (1) NZ189974A (xx)
PH (1) PH15168A (xx)
PL (2) PL117421B1 (xx)
PT (1) PT69384A (xx)
RO (1) RO78155A (xx)
YU (1) YU71279A (xx)
ZA (1) ZA791522B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395560A (en) * 1982-05-24 1983-07-26 Eli Lilly And Company Preparation of 6a,10a-trans-hexahydrodibenzopyranones
DE69910373T2 (de) * 1998-05-04 2004-04-01 The University Of Connecticut, Farmington Analgetische und immunomodulierende cannabinoiden
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
DE60033834T2 (de) 1999-10-18 2007-11-15 The University Of Connecticut, Farmington Für periphäre cannabinoid-rezeptoren selektive liganden
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US7119108B1 (en) * 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
JP2004532185A (ja) * 2001-01-26 2004-10-21 ユニバーシティ オブ コネチカット 新規なカンナビミメティックリガンド
DE60237431D1 (de) 2001-01-29 2010-10-07 Univ Connecticut Rezeptor-selektive cannabimimetische aminoalkylindole
JP4312594B2 (ja) * 2001-07-13 2009-08-12 ユニバーシティ オブ コネチカット 新規な二環式及び三環式カンナビノイド
WO2003035005A2 (en) * 2001-10-26 2003-05-01 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
CN1678303A (zh) 2002-08-23 2005-10-05 康涅狄格大学 具有治疗作用的酮类大麻类
US7674922B2 (en) * 2005-09-29 2010-03-09 Albany Molecular Research, Inc. Process for production of delta-9-tetrahydrocannabinol
CA2638940C (en) * 2008-08-28 2009-09-15 Dalton Chemical Laboratories Inc. Improved synthesis of hexahydrodibenzopyranones
US12029718B2 (en) 2021-11-09 2024-07-09 Cct Sciences, Llc Process for production of essentially pure delta-9-tetrahydrocannabinol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582564A (en) * 1976-07-06 1981-01-14 Lilly Co Eli Dibenzopyrans
US4054581A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor
GB1579137A (en) * 1976-07-06 1980-11-12 Lilly Co Eli 5-isopropylidene-2,6-methano-3,4,5,6-tetrahydro-2h-1-benzoxocins

Also Published As

Publication number Publication date
IL56944A0 (en) 1979-05-31
CA1132589A (en) 1982-09-28
JPS54132575A (en) 1979-10-15
DD143612A5 (de) 1980-09-03
HU179972B (en) 1983-01-28
EG13932A (en) 1983-03-31
EP0004753B1 (en) 1982-05-26
US4171315A (en) 1979-10-16
DK132779A (da) 1979-10-01
IE791293L (en) 1979-09-30
IL56944A (en) 1982-08-31
CS208493B2 (en) 1981-09-15
AT363469B (de) 1981-08-10
PL117421B1 (en) 1981-08-31
AU4536179A (en) 1979-10-04
DE2962942D1 (en) 1982-07-15
GB2017703B (en) 1982-10-06
CS208491B2 (en) 1981-09-15
YU71279A (en) 1982-10-31
PH15168A (en) 1982-08-31
FI790981A (fi) 1979-10-01
NZ189974A (en) 1980-10-08
LU81086A1 (fr) 1979-06-19
EP0004753A1 (en) 1979-10-17
PT69384A (en) 1979-04-01
FR2421171B1 (xx) 1982-12-31
RO78155A (ro) 1982-02-01
JPS5927350B2 (ja) 1984-07-05
BG32851A3 (en) 1982-10-15
MX5532E (es) 1983-09-23
ES479066A1 (es) 1979-12-16
IE48446B1 (en) 1985-01-23
CH638198A5 (fr) 1983-09-15
FR2421171A1 (fr) 1979-10-26
PL123995B1 (en) 1982-12-31
GR71467B (xx) 1983-05-30
BG32850A3 (en) 1982-10-15
PL214573A1 (xx) 1980-03-10
ZA791522B (en) 1980-11-26
GB2017703A (en) 1979-10-10
ATA234679A (de) 1981-01-15
AU516719B2 (en) 1981-06-18

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19860331