JPS56128774A
(en)
*
|
1980-03-14 |
1981-10-08 |
Microbial Chem Res Found |
New physiologically active substance ebelactone and its preparation
|
CA1247547A
(fr)
*
|
1983-06-22 |
1988-12-28 |
Paul Hadvary |
Derives de leucine
|
US5260310A
(en)
*
|
1990-02-26 |
1993-11-09 |
Hoffmann-La Roche Inc. |
Oxetanone compounds and pharmaceutical compositions containing them
|
IL97148A
(en)
*
|
1990-02-26 |
1996-11-14 |
Hoffmann La Roche |
Oxtanones, the process for their preparation and the pharmaceutical preparations containing them
|
US5198358A
(en)
*
|
1991-08-28 |
1993-03-30 |
Merck & Co., Inc. |
Microorganism for producing C-31 desmethyl FR-900520 cyclic hemiketal immunosuppressant agent
|
US5221625A
(en)
*
|
1992-01-10 |
1993-06-22 |
Merck & Co., Inc. |
Cyclcic FR-900520 microbial biotransformation agent
|
CA2098167C
(fr)
*
|
1992-06-24 |
2006-12-19 |
Dorothea Isler |
Aliments pour humains et animaux contenant un inhibiteur de la lipase
|
US5283183A
(en)
*
|
1992-09-28 |
1994-02-01 |
Merck & Co., Inc. |
Cyclic FR-900520 microbial biotransformation agent
|
US5268282A
(en)
*
|
1992-09-28 |
1993-12-07 |
Merck & Co., Inc. |
Cyclic FR-900520 microbial biotransformation agent
|
US5268281A
(en)
*
|
1992-09-28 |
1993-12-07 |
Merck & Co., Inc. |
Cyclic FR-900520 microbial biotransformation agent
|
US5290689A
(en)
*
|
1992-09-28 |
1994-03-01 |
Merck & Co., Inc. |
New cyclic FR-900520 microbial biotransformation agent
|
TW381025B
(en)
*
|
1993-08-05 |
2000-02-01 |
Hoffmann La Roche |
Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor
|
CA2141527C
(fr)
*
|
1994-03-24 |
2001-03-13 |
Dennis G. Fontanilla |
Ruban couvre-joint pour l'isolation de tuyaux
|
US5474993A
(en)
*
|
1994-06-14 |
1995-12-12 |
Sterling Winthrop, Inc. |
Lactam inhibitors of cholesterol esterase
|
JP2002524410A
(ja)
|
1998-09-08 |
2002-08-06 |
スミスクライン・ビーチャム・コーポレイション |
リプスタチン誘導体−可溶性繊維錠剤
|
US6514748B1
(en)
*
|
1999-03-19 |
2003-02-04 |
Council Of Scientific And Industrial Research |
Strain of streptomyces for the preparation of an alkaline protease inhibitor
|
US6348492B1
(en)
*
|
1999-10-29 |
2002-02-19 |
2Pro Chemical |
Oxetanone derivatives
|
AU1347701A
(en)
*
|
1999-10-29 |
2001-05-14 |
John Jason Gentry Mullins |
Oxetanone derivatives
|
US6342519B2
(en)
*
|
1999-10-29 |
2002-01-29 |
2 Pro Chemical |
Oxetanone derivatives
|
SI1296656T1
(sl)
*
|
2000-06-27 |
2006-12-31 |
Hoffmann La Roche |
Postopek priprave sestavka
|
US7105526B2
(en)
|
2002-06-28 |
2006-09-12 |
Banyu Pharmaceuticals Co., Ltd. |
Benzimidazole derivatives
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
WO2005028438A1
(fr)
|
2003-09-22 |
2005-03-31 |
Banyu Pharmaceutical Co., Ltd. |
Nouveau derive de piperidine
|
WO2005051298A2
(fr)
|
2003-11-19 |
2005-06-09 |
Metabasis Therapeutics, Inc. |
Nouvelles substances thyromimetiques contenant du phosphore
|
US7074822B2
(en)
|
2004-02-23 |
2006-07-11 |
Solvay Pharmaceuticals Gmbh |
Alkyl carbamate-substituted β-lactones, process for their preparation, and pharmaceutical compositions containing them
|
EP2305352A1
(fr)
|
2004-04-02 |
2011-04-06 |
Merck Sharp & Dohme Corp. |
Inhibiteurs de la 5-alpha-reductase pour le traitement d'hommes aux troubles métaboliques et anthropométriques
|
CA2590533C
(fr)
*
|
2004-11-23 |
2010-09-07 |
Warner-Lambert Company Llc |
Derives d'acide 7-(2h-pyrazol-3-yl)-3, 5-dihyroxy-heptanoique comme inhibiteurs de hmg co-a reductase pour le traitement de l'hyperlipidemie
|
ES2574014T3
(es)
|
2005-05-30 |
2016-06-14 |
Msd K.K. |
Derivado de piperidina novedoso
|
EP1916239A4
(fr)
|
2005-08-10 |
2009-10-21 |
Banyu Pharma Co Ltd |
Composé de pyridone
|
EP1921065B1
(fr)
|
2005-08-24 |
2010-10-20 |
Banyu Pharmaceutical Co., Ltd. |
Dérivé phénylpyridone
|
WO2007029847A1
(fr)
|
2005-09-07 |
2007-03-15 |
Banyu Pharmaceutical Co., Ltd. |
Dérivé de pyridone substitué aromatique bicylique
|
BRPI0617621A2
(pt)
|
2005-10-21 |
2011-08-02 |
Novartis Ag |
combinação de compostos orgánicos
|
US7741317B2
(en)
|
2005-10-21 |
2010-06-22 |
Bristol-Myers Squibb Company |
LXR modulators
|
AU2006307046A1
(en)
|
2005-10-27 |
2007-05-03 |
Msd K.K. |
Novel benzoxathiin derivative
|
MY146564A
(en)
|
2005-11-10 |
2012-08-30 |
Msd Kk |
Aza-substituted spiro derivatives
|
US7888376B2
(en)
|
2005-11-23 |
2011-02-15 |
Bristol-Myers Squibb Company |
Heterocyclic CETP inhibitors
|
WO2008038692A1
(fr)
|
2006-09-28 |
2008-04-03 |
Banyu Pharmaceutical Co., Ltd. |
dÉrivÉ de diarylcÉtimine
|
US8404896B2
(en)
|
2006-12-01 |
2013-03-26 |
Bristol-Myers Squibb Company |
N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
|
AU2008233662B2
(en)
|
2007-04-02 |
2012-08-23 |
Msd K.K. |
Indoledione derivative
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
US7879802B2
(en)
|
2007-06-04 |
2011-02-01 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
CA2714617A1
(fr)
|
2008-03-06 |
2009-09-11 |
Banyu Pharmaceutical Co., Ltd. |
Derive d'alkylaminopyridine
|
US20110015198A1
(en)
|
2008-03-28 |
2011-01-20 |
Banyu Pharmaceutical Co., Inc. |
Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism
|
EP3239170B1
(fr)
|
2008-06-04 |
2019-03-20 |
Synergy Pharmaceuticals Inc. |
Agonistes de guanylate cyclase utile dans le traitement de troubles gastro-intestinaux, d'une inflammation, d'un cancer et d'autres troubles
|
EP2301936A1
(fr)
|
2008-06-19 |
2011-03-30 |
Banyu Pharmaceutical Co., Ltd. |
Dérivé de spirodiamine-diarylcétoxime
|
EP3241839B1
(fr)
|
2008-07-16 |
2019-09-04 |
Bausch Health Ireland Limited |
Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres
|
EP2319841A1
(fr)
|
2008-07-30 |
2011-05-11 |
Msd K.K. |
Dérivé de cycloalkylamine à noyaux fusionnés à (5 chaînons)-(5 chaînons) ou (5 chaînons) (6 chaînons)
|
CA2741125A1
(fr)
|
2008-10-22 |
2010-04-29 |
Merck Sharp & Dohme Corp. |
Nouveaux derives de benzimidazole cycliques utiles comme agents anti-diabetiques
|
WO2010051206A1
(fr)
|
2008-10-31 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Nouveaux agents antidiabétiques utiles avec des dérivés de benzimidazole cycliques
|
US20120046364A1
(en)
|
2009-02-10 |
2012-02-23 |
Metabasis Therapeutics, Inc. |
Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
|
US8895596B2
(en)
|
2010-02-25 |
2014-11-25 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
EP2571860A1
(fr)
|
2010-05-21 |
2013-03-27 |
Pfizer Inc |
2-phénylbenzoylamides
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
EP2677869B1
(fr)
|
2011-02-25 |
2017-11-08 |
Merck Sharp & Dohme Corp. |
Nouveaux dérivés d'azabenzimidazole cyclique utiles en tant qu'agents antidiabétiques
|
EP2680874A2
(fr)
|
2011-03-04 |
2014-01-08 |
Pfizer Inc |
Peptides de type edn3 et utilisations associées
|
AU2013296470B2
(en)
|
2012-08-02 |
2016-03-17 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
AU2014219020A1
(en)
|
2013-02-22 |
2015-07-23 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
WO2014139388A1
(fr)
|
2013-03-14 |
2014-09-18 |
Merck Sharp & Dohme Corp. |
Nouveaux dérivés d'indole utiles en tant qu'agents antidiabétiques
|
US9708367B2
(en)
|
2013-03-15 |
2017-07-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase and their uses
|
CA2905435A1
(fr)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Compositions utiles pour le traitement de troubles gastro-intestinaux
|
BR112015026513A2
(pt)
|
2013-04-17 |
2017-07-25 |
Pfizer |
derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
|
JP6606491B2
(ja)
|
2013-06-05 |
2019-11-13 |
シナジー ファーマシューティカルズ インコーポレイテッド |
グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法
|
WO2015051496A1
(fr)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Composés tricycliques antidiabétiques
|
JP6769963B2
(ja)
|
2014-08-29 |
2020-10-14 |
ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ |
α−アミノ−β−カルボキシムコン酸セミアルデヒド脱炭酸酵素の阻害剤
|
WO2016055901A1
(fr)
|
2014-10-08 |
2016-04-14 |
Pfizer Inc. |
Composés d'amide substitué
|
AU2017342083A1
(en)
|
2016-10-14 |
2019-04-11 |
Tes Pharma S.R.L. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
EP3551176A4
(fr)
|
2016-12-06 |
2020-06-24 |
Merck Sharp & Dohme Corp. |
Composés hétérocycliques antidiabétiques
|
EP3558298A4
(fr)
|
2016-12-20 |
2020-08-05 |
Merck Sharp & Dohme Corp. |
Composés de spirochromane antidiabétiques
|
KR20210111248A
(ko)
|
2018-11-20 |
2021-09-10 |
테스 파마 에스.알.엘. |
α-아미노-β-카르복시뮤콘산 세미알데하이드 데카르복실라제의 저해제
|
MX2021008533A
(es)
|
2019-01-18 |
2021-08-19 |
Astrazeneca Ab |
Inhibidores de la pcsk9 y metodos de uso de los mismos.
|