BE858451A - Nouveaux derives amide de la vlb, de la leurosidine, de la leurocristine et d'autres alcaloides dimeres apparentes - Google Patents

Nouveaux derives amide de la vlb, de la leurosidine, de la leurocristine et d'autres alcaloides dimeres apparentes

Info

Publication number
BE858451A
BE858451A BE1008362A BE1008362A BE858451A BE 858451 A BE858451 A BE 858451A BE 1008362 A BE1008362 A BE 1008362A BE 1008362 A BE1008362 A BE 1008362A BE 858451 A BE858451 A BE 858451A
Authority
BE
Belgium
Prior art keywords
leurocristine
leurosidine
vlb
dimeric alkaloids
related dimeric
Prior art date
Application number
BE1008362A
Other languages
English (en)
French (fr)
Inventor
G J Cullinan
K Gerzon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE858451A publication Critical patent/BE858451A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BE1008362A 1976-09-08 1977-09-07 Nouveaux derives amide de la vlb, de la leurosidine, de la leurocristine et d'autres alcaloides dimeres apparentes BE858451A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72165076A 1976-09-08 1976-09-08

Publications (1)

Publication Number Publication Date
BE858451A true BE858451A (fr) 1978-03-07

Family

ID=24898757

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1008362A BE858451A (fr) 1976-09-08 1977-09-07 Nouveaux derives amide de la vlb, de la leurosidine, de la leurocristine et d'autres alcaloides dimeres apparentes

Country Status (27)

Country Link
JP (1) JPS5340799A (pl)
AR (3) AR226411A1 (pl)
AT (1) AT360513B (pl)
AU (1) AU511055B2 (pl)
BE (1) BE858451A (pl)
CA (1) CA1082179A (pl)
CH (1) CH631990A5 (pl)
DD (1) DD133055A5 (pl)
DE (1) DE2739443A1 (pl)
DK (1) DK146822C (pl)
ES (1) ES462229A1 (pl)
FR (1) FR2364220A1 (pl)
GB (1) GB1586709A (pl)
GR (1) GR69783B (pl)
HU (1) HU180722B (pl)
IE (1) IE45558B1 (pl)
IL (1) IL52731A0 (pl)
MX (1) MX4740E (pl)
NL (1) NL7709806A (pl)
NZ (1) NZ184932A (pl)
PH (1) PH14771A (pl)
PL (1) PL104309B1 (pl)
PT (1) PT66984B (pl)
RO (3) RO77921A (pl)
SE (1) SE434953B (pl)
YU (1) YU209777A (pl)
ZA (1) ZA774988B (pl)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
AR225153A1 (es) * 1978-10-10 1982-02-26 Lilly Co Eli Un procedimiento para la preparacion de sulfato de vindesina
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
CA1335686C (fr) * 1986-01-13 1995-05-23 Rao K. S. P. Bhushana Vinblastine et composition pharmaceutique les contenant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms

Also Published As

Publication number Publication date
ZA774988B (en) 1979-03-28
RO77922A (ro) 1981-12-25
ATA644277A (de) 1980-06-15
CH631990A5 (en) 1982-09-15
CA1082179A (en) 1980-07-22
PT66984B (en) 1979-02-13
PH14771A (en) 1981-12-09
FR2364220A1 (fr) 1978-04-07
JPS624398B2 (pl) 1987-01-30
SE434953B (sv) 1984-08-27
NZ184932A (en) 1979-11-01
YU209777A (en) 1982-08-31
IE771700L (en) 1978-03-08
IE45558B1 (en) 1982-09-22
AU2803977A (en) 1979-02-22
IL52731A0 (en) 1977-10-31
GR69783B (pl) 1982-07-07
PL200607A1 (pl) 1978-05-22
HU180722B (en) 1983-04-29
DE2739443C2 (pl) 1991-08-14
RO77921A (ro) 1981-12-25
MX4740E (es) 1982-08-25
GB1586709A (en) 1981-03-25
PL104309B1 (pl) 1979-08-31
DE2739443A1 (de) 1978-03-09
FR2364220B1 (pl) 1980-04-25
PT66984A (en) 1977-10-01
RO72474A (ro) 1982-05-10
ES462229A1 (es) 1978-07-16
AR231643A1 (es) 1985-01-31
JPS5340799A (en) 1978-04-13
NL7709806A (nl) 1978-03-10
AT360513B (de) 1981-01-12
DD133055A5 (de) 1978-11-29
DK398577A (da) 1978-03-09
SE7710059L (sv) 1978-03-09
AR230642A1 (es) 1984-05-31
DK146822C (da) 1984-06-25
AU511055B2 (en) 1980-07-24
AR226411A1 (es) 1982-07-15
DK146822B (da) 1984-01-16

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19920930