BE855406A - Procede de preparation de 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz (e) indole et produits obtenus, ainsi que les intermediaires - Google Patents
Procede de preparation de 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz (e) indole et produits obtenus, ainsi que les intermediairesInfo
- Publication number
- BE855406A BE855406A BE178212A BE178212A BE855406A BE 855406 A BE855406 A BE 855406A BE 178212 A BE178212 A BE 178212A BE 178212 A BE178212 A BE 178212A BE 855406 A BE855406 A BE 855406A
- Authority
- BE
- Belgium
- Prior art keywords
- phenylbenz
- intermediaries
- indole
- hydroxyphenyl
- dihydro
- Prior art date
Links
- HAWWPSYXSLJRBO-UHFFFAOYSA-N fendosal Chemical compound C1=C(O)C(C(=O)O)=CC(N2C(=CC=3C4=CC=CC=C4CCC=32)C=2C=CC=CC=2)=C1 HAWWPSYXSLJRBO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/692,331 US4066659A (en) | 1976-06-03 | 1976-06-03 | Method of preparation of 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz (e) indole and valuable intermediates related thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE855406A true BE855406A (fr) | 1977-12-05 |
Family
ID=24780138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE178212A BE855406A (fr) | 1976-06-03 | 1977-06-03 | Procede de preparation de 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz (e) indole et produits obtenus, ainsi que les intermediaires |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4066659A (OSRAM) |
| JP (1) | JPS5325556A (OSRAM) |
| AT (1) | AT353786B (OSRAM) |
| BE (1) | BE855406A (OSRAM) |
| CA (1) | CA1105936A (OSRAM) |
| CH (1) | CH629774A5 (OSRAM) |
| DE (1) | DE2724601A1 (OSRAM) |
| DK (1) | DK145296C (OSRAM) |
| ES (1) | ES459256A1 (OSRAM) |
| FI (1) | FI65059C (OSRAM) |
| HU (1) | HU176801B (OSRAM) |
| IT (1) | IT1076781B (OSRAM) |
| NL (1) | NL7705807A (OSRAM) |
| SE (1) | SE425391B (OSRAM) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1356431A (en) * | 1971-06-03 | 1974-06-12 | Wyeth John & Brother Ltd | Substituted benz-g-indoles |
| US3931407A (en) * | 1973-03-01 | 1976-01-06 | American Hoechst Corporation | Method of treatment with and compositions containing condensed pyrroles bearing an N-phenyl substituent |
-
1976
- 1976-06-03 US US05/692,331 patent/US4066659A/en not_active Expired - Lifetime
-
1977
- 1977-05-26 NL NL7705807A patent/NL7705807A/xx not_active Application Discontinuation
- 1977-05-28 ES ES459256A patent/ES459256A1/es not_active Expired
- 1977-05-31 CH CH664677A patent/CH629774A5/de not_active IP Right Cessation
- 1977-06-01 DE DE19772724601 patent/DE2724601A1/de active Granted
- 1977-06-01 IT IT24269/77A patent/IT1076781B/it active
- 1977-06-01 FI FI771747A patent/FI65059C/fi not_active IP Right Cessation
- 1977-06-02 HU HU77HO1992A patent/HU176801B/hu not_active IP Right Cessation
- 1977-06-02 AT AT392877A patent/AT353786B/de not_active IP Right Cessation
- 1977-06-02 DK DK243677A patent/DK145296C/da active
- 1977-06-02 CA CA279,689A patent/CA1105936A/en not_active Expired
- 1977-06-03 BE BE178212A patent/BE855406A/xx not_active IP Right Cessation
- 1977-06-03 JP JP6568277A patent/JPS5325556A/ja active Granted
- 1977-06-03 SE SE7706526A patent/SE425391B/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5325556A (en) | 1978-03-09 |
| HU176801B (en) | 1981-05-28 |
| SE7706526L (sv) | 1977-12-04 |
| SE425391B (sv) | 1982-09-27 |
| FI65059C (fi) | 1984-03-12 |
| AT353786B (de) | 1979-12-10 |
| DK243677A (da) | 1977-12-04 |
| NL7705807A (nl) | 1977-12-06 |
| CA1105936A (en) | 1981-07-28 |
| ES459256A1 (es) | 1978-03-01 |
| DK145296C (da) | 1983-03-14 |
| DK145296B (da) | 1982-10-25 |
| CH629774A5 (de) | 1982-05-14 |
| US4066659A (en) | 1978-01-03 |
| IT1076781B (it) | 1985-04-27 |
| DE2724601A1 (de) | 1977-12-22 |
| JPS6120546B2 (OSRAM) | 1986-05-22 |
| FI65059B (fi) | 1983-11-30 |
| DE2724601C2 (OSRAM) | 1988-03-03 |
| FI771747A7 (OSRAM) | 1977-12-04 |
| ATA392877A (de) | 1979-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: HOECHST A.G. Effective date: 19900630 |