BE852324A - Procede de production de nouveaux composes antigonistes d'histamine-h2 - Google Patents

Procede de production de nouveaux composes antigonistes d'histamine-h2

Info

Publication number
BE852324A
BE852324A BE175676A BE175676A BE852324A BE 852324 A BE852324 A BE 852324A BE 175676 A BE175676 A BE 175676A BE 175676 A BE175676 A BE 175676A BE 852324 A BE852324 A BE 852324A
Authority
BE
Belgium
Prior art keywords
antigonist
histamine
compounds
new
production
Prior art date
Application number
BE175676A
Other languages
English (en)
French (fr)
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of BE852324A publication Critical patent/BE852324A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26—Radicals substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
BE175676A 1976-03-11 1977-03-10 Procede de production de nouveaux composes antigonistes d'histamine-h2 BE852324A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9750/76A GB1574214A (en) 1976-03-11 1976-03-11 Amidines

Publications (1)

Publication Number Publication Date
BE852324A true BE852324A (fr) 1977-09-12

Family

ID=9878056

Family Applications (1)

Application Number Title Priority Date Filing Date
BE175676A BE852324A (fr) 1976-03-11 1977-03-10 Procede de production de nouveaux composes antigonistes d'histamine-h2

Country Status (34)

Country Link
US (4) US4118502A (nl)
JP (1) JPS52136170A (nl)
AR (2) AR218242A1 (nl)
AT (1) AT358576B (nl)
AU (1) AU506146B2 (nl)
BE (1) BE852324A (nl)
CA (1) CA1075700A (nl)
CS (1) CS196352B2 (nl)
DD (1) DD128616A5 (nl)
DE (1) DE2710326A1 (nl)
DK (1) DK96477A (nl)
ES (1) ES456735A1 (nl)
FI (1) FI770736A (nl)
FR (1) FR2343730A1 (nl)
GB (1) GB1574214A (nl)
GR (1) GR62562B (nl)
HU (1) HU176611B (nl)
IE (1) IE44786B1 (nl)
IL (1) IL51530A (nl)
IN (1) IN147036B (nl)
IT (1) IT1075494B (nl)
LU (1) LU76930A1 (nl)
MW (1) MW977A1 (nl)
NL (1) NL7702533A (nl)
NO (1) NO770854L (nl)
NZ (1) NZ183396A (nl)
OA (1) OA05595A (nl)
PL (1) PL105620B1 (nl)
PT (1) PT66255B (nl)
RO (1) RO73006A (nl)
SE (1) SE7702771L (nl)
SU (2) SU814274A3 (nl)
ZA (1) ZA771018B (nl)
ZM (1) ZM2677A1 (nl)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242351A (en) * 1979-05-07 1980-12-30 Imperial Chemical Industries Limited Antisecretory oxadiazoles and pharmaceutical compositions containing them
US4242350A (en) 1978-05-24 1980-12-30 Imperial Chemical Industries Limited Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them
US4282213A (en) 1978-06-06 1981-08-04 Smith Kline & French Laboratories Limited Amidino and guanidino phosphonates

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210658A (en) * 1977-09-08 1980-07-01 Smith Kline & French Laboratories Limited Amidinosulphonic acid derivatives
IL57415A (en) * 1978-05-30 1984-08-31 Smith Kline French Lab Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them
IT8020734A0 (it) * 1980-03-18 1980-03-18 Turconi Franco Quadrata (2 aminoetil)-tiometilderivati del 4-metil-5 aperta par.chiusa par. quadrata-imidazolo adattivita' terapeutica.
US4382090A (en) * 1980-10-02 1983-05-03 Eli Lilly And Company N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
IT1201523B (it) * 1982-05-18 1989-02-02 Angeli Inst Spa Eterociclilfenilfomramidine,processi per la loro preparazione e loro uso farmaceutico
US5399706A (en) * 1993-03-02 1995-03-21 H. B. Fuller Licensing & Financing, Inc. Imidazolidinone diamine and derivatives thereof
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758146A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
US3808336A (en) * 1970-06-25 1974-04-30 Smithkline Corp Pharmaceutical compositions and methods of inhibiting histamine activity with thiourea derivatives
US3734924A (en) * 1970-10-14 1973-05-22 Smith Kline French Lab Carboxamidines
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1421999A (en) 1973-02-08 1976-01-21 Smith Kline French Lab Heterocyclic containing sulphoxides
US4056620A (en) * 1973-02-08 1977-11-01 Smith Kline & French Laboratories Limited Sulphoxides
US4046907A (en) * 1973-05-17 1977-09-06 Smith Kline & French Laboratories Limited Imidazole alkylaminoethylene compounds
US4025527A (en) * 1973-07-13 1977-05-24 Smith Kline & French Laboratories Limited Certain thiazoles and oxazoles
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
US4140783A (en) * 1976-05-24 1979-02-20 Smith Kline & French Laboratories Limited Isothiazole and isoxazole sulphoxides
GB1602458A (en) 1977-05-05 1981-11-11 Smith Kline French Lab Bisamidines as histamine h2-antagonists

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242350A (en) 1978-05-24 1980-12-30 Imperial Chemical Industries Limited Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them
US4282213A (en) 1978-06-06 1981-08-04 Smith Kline & French Laboratories Limited Amidino and guanidino phosphonates
US4242351A (en) * 1979-05-07 1980-12-30 Imperial Chemical Industries Limited Antisecretory oxadiazoles and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IN147036B (nl) 1979-10-27
FR2343730A1 (fr) 1977-10-07
US4308275A (en) 1981-12-29
ZA771018B (en) 1978-01-25
PL196568A1 (pl) 1978-01-16
MW977A1 (en) 1978-08-09
HU176611B (en) 1981-03-28
AU2315577A (en) 1978-09-14
AR219955A1 (es) 1980-09-30
GR62562B (en) 1979-05-10
SU731896A3 (ru) 1980-04-30
FI770736A (nl) 1977-09-12
PL105620B1 (pl) 1979-10-31
SE7702771L (sv) 1977-09-14
IL51530A (en) 1981-03-31
AU506146B2 (en) 1979-12-13
ATA154177A (de) 1980-02-15
NL7702533A (nl) 1977-09-13
IT1075494B (it) 1985-04-22
NZ183396A (en) 1979-03-28
US4118502A (en) 1978-10-03
US4438127A (en) 1984-03-20
GB1574214A (en) 1980-09-03
DD128616A5 (de) 1977-11-30
ZM2677A1 (en) 1978-07-21
ES456735A1 (es) 1978-06-01
PT66255B (en) 1978-08-07
LU76930A1 (nl) 1977-07-12
IE44786L (en) 1977-09-11
DE2710326A1 (de) 1977-09-15
DK96477A (da) 1977-09-12
OA05595A (fr) 1981-04-30
US4395419A (en) 1983-07-26
PT66255A (en) 1977-04-01
CS196352B2 (en) 1980-03-31
AT358576B (de) 1980-09-25
SU814274A3 (ru) 1981-03-15
FR2343730B1 (nl) 1980-01-11
IE44786B1 (en) 1982-03-24
CA1075700A (en) 1980-04-15
AR218242A1 (es) 1980-05-30
RO73006A (ro) 1982-04-12
JPS52136170A (en) 1977-11-14
NO770854L (no) 1977-09-13

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SMITH KLINE & FRENCH LABORATORIES LTD

Effective date: 19840310