BE852252A - Nouveaux 5-(1,1-diphenyl-3-(5 ou 6-hydroxy ou-alcanoyloxy inferieur-2-aza-2-bicyclo(2,2,2)octoyl)propyl)-2-alkyl)1,3,4-oxodiazoles - Google Patents
Nouveaux 5-(1,1-diphenyl-3-(5 ou 6-hydroxy ou-alcanoyloxy inferieur-2-aza-2-bicyclo(2,2,2)octoyl)propyl)-2-alkyl)1,3,4-oxodiazolesInfo
- Publication number
- BE852252A BE852252A BE175614A BE175614A BE852252A BE 852252 A BE852252 A BE 852252A BE 175614 A BE175614 A BE 175614A BE 175614 A BE175614 A BE 175614A BE 852252 A BE852252 A BE 852252A
- Authority
- BE
- Belgium
- Prior art keywords
- oxodiazoles
- alcanoyloxy
- inferieur
- octoyl
- aza
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/665,609 US4013668A (en) | 1976-03-10 | 1976-03-10 | 5-(1,1-diphenyl-3-(5- or 6-hydroxy-2-azabicyclo(2.2.2)oct-2-yl)propyl)-2-alkyl-1,3,4-oxadiazoles and related compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BE852252A true BE852252A (fr) | 1977-09-09 |
Family
ID=24670819
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE175614A BE852252A (fr) | 1976-03-10 | 1977-03-09 | Nouveaux 5-(1,1-diphenyl-3-(5 ou 6-hydroxy ou-alcanoyloxy inferieur-2-aza-2-bicyclo(2,2,2)octoyl)propyl)-2-alkyl)1,3,4-oxodiazoles |
Country Status (17)
Country | Link |
---|---|
US (1) | US4013668A (fr) |
JP (1) | JPS5951955B2 (fr) |
AT (1) | AT350559B (fr) |
AU (1) | AU505650B2 (fr) |
BE (1) | BE852252A (fr) |
CA (1) | CA1078386A (fr) |
CH (1) | CH627467A5 (fr) |
DE (1) | DE2710242A1 (fr) |
DK (1) | DK103777A (fr) |
ES (1) | ES456687A1 (fr) |
FR (1) | FR2343740A2 (fr) |
GB (1) | GB1524653A (fr) |
IE (1) | IE44639B1 (fr) |
NL (1) | NL7702537A (fr) |
NZ (1) | NZ183540A (fr) |
SE (1) | SE7702640L (fr) |
ZA (1) | ZA771428B (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0241180A (ja) * | 1988-07-29 | 1990-02-09 | Shinji Kanda | 耐火避難用カプセル |
ATE154354T1 (de) * | 1991-02-11 | 1997-06-15 | Merck Sharp & Dohme | Azabicyclische verbindungen, diese enthaltende pharmazeutische zubereitungen und ihre therapeutische verwendung |
US6190691B1 (en) | 1994-04-12 | 2001-02-20 | Adolor Corporation | Methods for treating inflammatory conditions |
US5962477A (en) * | 1994-04-12 | 1999-10-05 | Adolor Corporation | Screening methods for cytokine inhibitors |
US6573282B1 (en) | 1995-09-12 | 2003-06-03 | Adolor Corporation | Peripherally active anti-hyperalgesic opiates |
US5849761A (en) * | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
US5667773A (en) * | 1996-03-12 | 1997-09-16 | Adolor Corporation | Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic conditions therewith |
US6353004B1 (en) | 1997-07-14 | 2002-03-05 | Adolor Coporation | Peripherally acting anti-pruritic opiates |
US20030158220A1 (en) * | 1997-11-03 | 2003-08-21 | Foss Joseph F. | Use of methylnaltrexone and related compounds to treat chronic opioid use side effects |
PL2368553T3 (pl) * | 2003-04-08 | 2015-05-29 | Progenics Pharm Inc | Preparaty farmaceutyczne zawierające metylonaltrekson |
AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
TW200817048A (en) * | 2006-09-08 | 2008-04-16 | Wyeth Corp | Dry powder compound formulations and uses thereof |
ES2540551T3 (es) * | 2007-03-29 | 2015-07-10 | Wyeth Llc | Antagonistas de receptores opioides periféricos y usos de los mismos |
AU2008233129B2 (en) * | 2007-03-29 | 2014-03-20 | Progenics Pharmaceuticals, Inc. | Peripheral opioid receptor antagonists and uses thereof |
JP2010522756A (ja) | 2007-03-29 | 2010-07-08 | プロジェニックス ファーマシューティカルズ,インコーポレーテッド | 結晶形およびその使用 |
CN101959892B (zh) * | 2008-02-06 | 2014-01-08 | 普罗热尼奇制药公司 | (r),(r)-2,2’-二-甲基纳曲酮的制备和用途 |
WO2010029313A1 (fr) * | 2008-09-11 | 2010-03-18 | Summit Corporation Plc. | Composés anti-infectieux |
CA2676881C (fr) | 2008-09-30 | 2017-04-25 | Wyeth | Antagonistes de recepteurs opioides peripheriques, et leurs utilisations |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3917615A (en) * | 1974-04-01 | 1975-11-04 | Searle & Co | 1,1-Diaryl-1-oxadiazol-alkylamines |
-
1976
- 1976-03-10 US US05/665,609 patent/US4013668A/en not_active Expired - Lifetime
-
1977
- 1977-03-09 AT AT157477A patent/AT350559B/de not_active IP Right Cessation
- 1977-03-09 CH CH295177A patent/CH627467A5/de not_active IP Right Cessation
- 1977-03-09 JP JP52025851A patent/JPS5951955B2/ja not_active Expired
- 1977-03-09 CA CA273,594A patent/CA1078386A/fr not_active Expired
- 1977-03-09 BE BE175614A patent/BE852252A/fr not_active IP Right Cessation
- 1977-03-09 AU AU23029/77A patent/AU505650B2/en not_active Expired
- 1977-03-09 DE DE19772710242 patent/DE2710242A1/de not_active Withdrawn
- 1977-03-09 ES ES456687A patent/ES456687A1/es not_active Expired
- 1977-03-09 ZA ZA00771428A patent/ZA771428B/xx unknown
- 1977-03-09 DK DK103777A patent/DK103777A/da unknown
- 1977-03-09 SE SE7702640A patent/SE7702640L/xx unknown
- 1977-03-09 NL NL7702537A patent/NL7702537A/xx not_active Application Discontinuation
- 1977-03-09 IE IE515/77A patent/IE44639B1/en unknown
- 1977-03-09 NZ NZ183540A patent/NZ183540A/xx unknown
- 1977-03-09 GB GB10031/77A patent/GB1524653A/en not_active Expired
- 1977-03-10 FR FR7707155A patent/FR2343740A2/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5951955B2 (ja) | 1984-12-17 |
ZA771428B (en) | 1978-10-25 |
FR2343740B2 (fr) | 1980-06-20 |
AU2302977A (en) | 1978-09-14 |
JPS52108999A (en) | 1977-09-12 |
ES456687A1 (es) | 1978-02-01 |
AU505650B2 (en) | 1979-11-29 |
NL7702537A (nl) | 1977-09-13 |
DE2710242A1 (de) | 1977-09-22 |
CH627467A5 (de) | 1982-01-15 |
IE44639L (en) | 1977-09-10 |
FR2343740A2 (fr) | 1977-10-07 |
DK103777A (da) | 1977-09-11 |
US4013668A (en) | 1977-03-22 |
NZ183540A (en) | 1980-05-27 |
IE44639B1 (en) | 1982-02-10 |
CA1078386A (fr) | 1980-05-27 |
GB1524653A (en) | 1978-09-13 |
AT350559B (de) | 1979-06-11 |
ATA157477A (de) | 1978-11-15 |
SE7702640L (sv) | 1977-09-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: G.D. SEARLE & CO. Effective date: 19850309 |