BE849311A - Nouveau procede de synthese de la 3',4'-didesoxykanamycine b. - Google Patents

Nouveau procede de synthese de la 3',4'-didesoxykanamycine b.

Info

Publication number
BE849311A
BE849311A BE173181A BE173181A BE849311A BE 849311 A BE849311 A BE 849311A BE 173181 A BE173181 A BE 173181A BE 173181 A BE173181 A BE 173181A BE 849311 A BE849311 A BE 849311A
Authority
BE
Belgium
Prior art keywords
didesoxykanamycin
synthesis
new process
new
Prior art date
Application number
BE173181A
Other languages
English (en)
French (fr)
Inventor
H Umezawa
S Umezawa
T Tsuchiya
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE849311A publication Critical patent/BE849311A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BE173181A 1975-12-11 1976-12-10 Nouveau procede de synthese de la 3',4'-didesoxykanamycine b. BE849311A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50146903A JPS6029720B2 (ja) 1975-12-11 1975-12-11 ３′，４′‐ジデオキシカナマイシンｂの新規な製造法

Publications (1)

Publication Number Publication Date
BE849311A true BE849311A (fr) 1977-06-10

Family

ID=15418164

Family Applications (1)

Application Number Title Priority Date Filing Date
BE173181A BE849311A (fr) 1975-12-11 1976-12-10 Nouveau procede de synthese de la 3',4'-didesoxykanamycine b.

Country Status (11)

Country Link
US (1) US4156078A (en:Method)
JP (1) JPS6029720B2 (en:Method)
BE (1) BE849311A (en:Method)
CA (1) CA1075684A (en:Method)
DE (1) DE2655731C3 (en:Method)
DK (1) DK159787C (en:Method)
FR (1) FR2336412A1 (en:Method)
GB (1) GB1555661A (en:Method)
HU (1) HU176356B (en:Method)
NL (1) NL7613706A (en:Method)
YU (3) YU41292B (en:Method)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6052719B2 (ja) * 1976-12-16 1985-11-20 財団法人微生物化学研究会 ３′，４′−ジデオキシカナマイシンｂの新規な製造法
JPS5581897A (en) * 1978-12-14 1980-06-20 Microbial Chem Res Found Preparation of 1-n-isoseryl-or 1-n-(l-4-amino-2-hydroxybutyryl)-3',4'-dideoxykanamycin b
JPS55105699A (en) * 1979-02-05 1980-08-13 Microbial Chem Res Found 3',4'-dideoxykanamycin a and its 1-n-aminoalkanoyl derivative
JPS5643297A (en) * 1979-09-19 1981-04-21 Microbial Chem Res Found 6"-deoxydibeckacin or 4",6"-dideoxydibeckacin, their 1-n-acyl derivative, and their preparation
JPS5663993A (en) * 1979-10-30 1981-05-30 Microbial Chem Res Found Novel preparation of tobramycin
US4438109A (en) 1980-07-25 1984-03-20 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Tylosin derivatives
US4345070A (en) * 1980-09-29 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin
US5488038A (en) * 1992-11-27 1996-01-30 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Dibekacin derivatives and arbekacin derivatives active against resistant bacteria
CN101575354B (zh) * 2009-05-26 2013-03-13 北京化工大学 阿贝卡星及其中间体地贝卡星的合成方法
CN102786564B (zh) * 2011-05-19 2015-05-13 北京化工大学 阿贝卡星及其中间体地贝卡星的合成新方法
CN106946957B (zh) * 2017-05-11 2019-11-08 常州方圆制药有限公司 阿贝卡星中间体的制备方法
CA3065900A1 (en) * 2017-06-05 2018-12-13 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
CN115716856B (zh) * 2022-11-14 2025-04-25 北京耀诚惠仁科技有限公司 一种合成氨基糖苷类抗生素阿贝卡星的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1349302A (en) * 1970-07-29 1974-04-03 Microbial Chem Res Found 3,-4,-dideoxykanamycin b active against resistant bacteria and its synthesis
USRE28647E (en) 1971-06-02 1975-12-09 Preparation of 3-4 dideoxykanamycin B active against resistant bacteria
US3929762A (en) * 1972-08-23 1975-12-30 Microbial Chem Res Found 3{40 -Deoxy derivatives of neamine and its related aminoglycosidic antibiotics, and the production thereof
US3868360A (en) * 1972-10-24 1975-02-25 Schering Corp Process for preparing 2-deroxy-3-desamino-2,3-epimino-aminoglycosides and intermediates useful therein

Also Published As

Publication number Publication date
FR2336412A1 (fr) 1977-07-22
YU42084B (en) 1988-04-30
YU41292B (en) 1987-02-28
YU299776A (en) 1982-06-30
DK159787B (da) 1990-12-03
HU176356B (en) 1981-01-28
DK554076A (da) 1977-06-12
YU146285A (en) 1986-06-30
DE2655731B2 (de) 1981-08-06
CA1075684A (en) 1980-04-15
JPS5271446A (en) 1977-06-14
DE2655731A1 (de) 1977-06-23
YU146385A (en) 1986-06-30
DE2655731C3 (de) 1982-04-29
NL7613706A (nl) 1977-06-14
DK159787C (da) 1991-04-22
US4156078A (en) 1979-05-22
YU42129B (en) 1988-04-30
GB1555661A (en) 1979-11-14
JPS6029720B2 (ja) 1985-07-12
FR2336412B1 (en:Method) 1980-09-26

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI

Effective date: 19961210