YU41292B - Process for the synthesis of 3,4-dideoxy-kanamycin b - Google Patents
Process for the synthesis of 3,4-dideoxy-kanamycin bInfo
- Publication number
- YU41292B YU41292B YU2997/76A YU299776A YU41292B YU 41292 B YU41292 B YU 41292B YU 2997/76 A YU2997/76 A YU 2997/76A YU 299776 A YU299776 A YU 299776A YU 41292 B YU41292 B YU 41292B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- dideoxy
- kanamycin
- synthesis
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 229960003807 dibekacin Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50146903A JPS6029720B2 (ja) | 1975-12-11 | 1975-12-11 | 3′,4′‐ジデオキシカナマイシンbの新規な製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
YU299776A YU299776A (en) | 1982-06-30 |
YU41292B true YU41292B (en) | 1987-02-28 |
Family
ID=15418164
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU2997/76A YU41292B (en) | 1975-12-11 | 1976-12-09 | Process for the synthesis of 3,4-dideoxy-kanamycin b |
YU1463/85A YU42084B (en) | 1975-12-11 | 1985-09-16 | Process for making 3,4-dideoxicanomicyne b |
YU1462/85A YU42129B (en) | 1975-12-11 | 1985-09-16 | Process for making 3,4-dideoxicanomicyne b |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU1463/85A YU42084B (en) | 1975-12-11 | 1985-09-16 | Process for making 3,4-dideoxicanomicyne b |
YU1462/85A YU42129B (en) | 1975-12-11 | 1985-09-16 | Process for making 3,4-dideoxicanomicyne b |
Country Status (11)
Country | Link |
---|---|
US (1) | US4156078A (xx) |
JP (1) | JPS6029720B2 (xx) |
BE (1) | BE849311A (xx) |
CA (1) | CA1075684A (xx) |
DE (1) | DE2655731C3 (xx) |
DK (1) | DK159787C (xx) |
FR (1) | FR2336412A1 (xx) |
GB (1) | GB1555661A (xx) |
HU (1) | HU176356B (xx) |
NL (1) | NL7613706A (xx) |
YU (3) | YU41292B (xx) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6052719B2 (ja) * | 1976-12-16 | 1985-11-20 | 財団法人微生物化学研究会 | 3′,4′−ジデオキシカナマイシンbの新規な製造法 |
JPS5581897A (en) * | 1978-12-14 | 1980-06-20 | Microbial Chem Res Found | Preparation of 1-n-isoseryl-or 1-n-(l-4-amino-2-hydroxybutyryl)-3',4'-dideoxykanamycin b |
JPS55105699A (en) * | 1979-02-05 | 1980-08-13 | Microbial Chem Res Found | 3',4'-dideoxykanamycin a and its 1-n-aminoalkanoyl derivative |
JPS5643297A (en) * | 1979-09-19 | 1981-04-21 | Microbial Chem Res Found | 6"-deoxydibeckacin or 4",6"-dideoxydibeckacin, their 1-n-acyl derivative, and their preparation |
JPS5663993A (en) * | 1979-10-30 | 1981-05-30 | Microbial Chem Res Found | Novel preparation of tobramycin |
US4438109A (en) | 1980-07-25 | 1984-03-20 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Tylosin derivatives |
US4345070A (en) * | 1980-09-29 | 1982-08-17 | Farmitalia Carlo Erba S.P.A. | Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin |
US5488038A (en) * | 1992-11-27 | 1996-01-30 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Dibekacin derivatives and arbekacin derivatives active against resistant bacteria |
CN101575354B (zh) * | 2009-05-26 | 2013-03-13 | 北京化工大学 | 阿贝卡星及其中间体地贝卡星的合成方法 |
CN102786564B (zh) * | 2011-05-19 | 2015-05-13 | 北京化工大学 | 阿贝卡星及其中间体地贝卡星的合成新方法 |
CN106946957B (zh) * | 2017-05-11 | 2019-11-08 | 常州方圆制药有限公司 | 阿贝卡星中间体的制备方法 |
AU2018279318B2 (en) * | 2017-06-05 | 2022-09-01 | Eloxx Pharmaceuticals Ltd. | Aminoglycoside derivatives and uses thereof in treating genetic disorders |
CN115716856A (zh) * | 2022-11-14 | 2023-02-28 | 山东厚德精诚药业有限公司 | 一种合成氨基糖苷类抗生素阿贝卡星的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1349302A (en) * | 1970-07-29 | 1974-04-03 | Microbial Chem Res Found | 3,-4,-dideoxykanamycin b active against resistant bacteria and its synthesis |
US3929762A (en) * | 1972-08-23 | 1975-12-30 | Microbial Chem Res Found | 3{40 -Deoxy derivatives of neamine and its related aminoglycosidic antibiotics, and the production thereof |
US3868360A (en) * | 1972-10-24 | 1975-02-25 | Schering Corp | Process for preparing 2-deroxy-3-desamino-2,3-epimino-aminoglycosides and intermediates useful therein |
-
1975
- 1975-12-11 JP JP50146903A patent/JPS6029720B2/ja not_active Expired
-
1976
- 1976-11-24 GB GB49034/76A patent/GB1555661A/en not_active Expired
- 1976-11-26 US US05/745,015 patent/US4156078A/en not_active Expired - Lifetime
- 1976-12-08 CA CA267,459A patent/CA1075684A/en not_active Expired
- 1976-12-08 FR FR7637816A patent/FR2336412A1/fr active Granted
- 1976-12-09 DE DE2655731A patent/DE2655731C3/de not_active Expired
- 1976-12-09 DK DK554076A patent/DK159787C/da active
- 1976-12-09 HU HU76ZA397A patent/HU176356B/hu not_active IP Right Cessation
- 1976-12-09 YU YU2997/76A patent/YU41292B/xx unknown
- 1976-12-09 NL NL7613706A patent/NL7613706A/xx not_active Application Discontinuation
- 1976-12-10 BE BE173181A patent/BE849311A/xx not_active IP Right Cessation
-
1985
- 1985-09-16 YU YU1463/85A patent/YU42084B/xx unknown
- 1985-09-16 YU YU1462/85A patent/YU42129B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NL7613706A (nl) | 1977-06-14 |
GB1555661A (en) | 1979-11-14 |
DK159787B (da) | 1990-12-03 |
YU42084B (en) | 1988-04-30 |
HU176356B (en) | 1981-01-28 |
DE2655731B2 (de) | 1981-08-06 |
DE2655731A1 (de) | 1977-06-23 |
DE2655731C3 (de) | 1982-04-29 |
JPS6029720B2 (ja) | 1985-07-12 |
DK554076A (da) | 1977-06-12 |
DK159787C (da) | 1991-04-22 |
FR2336412B1 (xx) | 1980-09-26 |
YU146385A (en) | 1986-06-30 |
US4156078A (en) | 1979-05-22 |
YU299776A (en) | 1982-06-30 |
YU146285A (en) | 1986-06-30 |
FR2336412A1 (fr) | 1977-07-22 |
JPS5271446A (en) | 1977-06-14 |
BE849311A (fr) | 1977-06-10 |
CA1075684A (en) | 1980-04-15 |
YU42129B (en) | 1988-04-30 |
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