BE842930A - Procede de preparation d'anthracyclines et d'anthracyclinones optiquement actives - Google Patents

Procede de preparation d'anthracyclines et d'anthracyclinones optiquement actives

Info

Publication number
BE842930A
BE842930A BE167900A BE167900A BE842930A BE 842930 A BE842930 A BE 842930A BE 167900 A BE167900 A BE 167900A BE 167900 A BE167900 A BE 167900A BE 842930 A BE842930 A BE 842930A
Authority
BE
Belgium
Prior art keywords
anthracyclinones
anthracyclins
optically active
preparing optically
preparing
Prior art date
Application number
BE167900A
Other languages
English (en)
Inventor
F Arcamone
L Bernardi
B Patelli
S Penco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE842930A publication Critical patent/BE842930A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
BE167900A 1976-06-14 1976-06-14 Procede de preparation d'anthracyclines et d'anthracyclinones optiquement actives BE842930A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7617955A FR2355028A1 (fr) 1976-06-14 1976-06-14 Procede pour la preparation de glycosides derives d'anthracyclines optiquement actives

Publications (1)

Publication Number Publication Date
BE842930A true BE842930A (fr) 1976-10-01

Family

ID=9174331

Family Applications (1)

Application Number Title Priority Date Filing Date
BE167900A BE842930A (fr) 1976-06-14 1976-06-14 Procede de preparation d'anthracyclines et d'anthracyclinones optiquement actives

Country Status (11)

Country Link
US (1) US4107423A (fr)
JP (1) JPS532463A (fr)
AT (2) AT345461B (fr)
BE (1) BE842930A (fr)
CA (1) CA1046510A (fr)
CH (1) CH622529A5 (fr)
DE (1) DE2626783C2 (fr)
FR (1) FR2355028A1 (fr)
GB (1) GB1509875A (fr)
NL (2) NL175300C (fr)
SE (2) SE421318B (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8551973B2 (en) 2008-12-23 2013-10-08 Gilead Pharmasset Llc Nucleoside analogs
US8716262B2 (en) 2008-12-23 2014-05-06 Gilead Pharmasset Llc Nucleoside phosphoramidates
US8716263B2 (en) 2008-12-23 2014-05-06 Gilead Pharmasset Llc Synthesis of purine nucleosides
US8759510B2 (en) 2008-06-11 2014-06-24 Gilead Pharmasset Llc Nucleoside cyclicphosphates
US8859756B2 (en) 2010-03-31 2014-10-14 Gilead Pharmasset Llc Stereoselective synthesis of phosphorus containing actives

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1567456A (en) * 1976-11-16 1980-05-14 Farmaceutici Italia Daunomycin derivatives
IL55431A (en) * 1978-08-24 1982-07-30 Yeda Res & Dev Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
GB2056443B (en) * 1979-08-20 1984-01-18 Hoffmann La Roche Cyclic compounds
JPS56135021A (en) * 1980-03-25 1981-10-22 Nippon Kokan Kk <Nkk> Lining for internal surface of welded part of steel pipe
CA1174669A (fr) * 1980-07-18 1984-09-18 Michael J. Broadhurst Glucosides d'anthracycline
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
US4540695A (en) * 1981-08-12 1985-09-10 Sumitomo Chemical Co., Ltd. Aminonaphthacene derivatives and their use
NL8300150A (nl) * 1982-01-26 1983-08-16 Erba Farmitalia Daunorubicine en doxorubicine-analoga, hun bereiding en toepassing.
FI75834C (fi) * 1982-05-24 1988-08-08 Erba Farmitalia Foerfarande foer framstaellning av antracyklinglykosidfoereningar.
JPS59212499A (ja) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 抗腫瘍性抗生物質アントラサイクリンの４−デメトキシ−３′−デアミノ−３′（４−モリホリニル）誘導体
US4831019A (en) * 1983-10-31 1989-05-16 Adria Laboratories, Inc. Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines
US4496485A (en) * 1983-11-25 1985-01-29 G. D. Searle & Co. Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
NZ224252A (en) 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
DE10155016A1 (de) * 2001-11-07 2003-05-15 Knoell Hans Forschung Ev Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung
US8846882B2 (en) * 2011-04-29 2014-09-30 Synbias Pharma Ag Method of producing 4-demethoxydaunorubicin
CN104151376B (zh) * 2014-06-23 2017-02-08 天津药物研究院新药评价有限公司 一种抗肿瘤药物及其合成方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3427300A (en) * 1965-11-12 1969-02-11 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3629231A (en) * 1968-05-23 1971-12-21 Biorex Laboratories Ltd Derivatives of glycyrrhetinic acid
FI51808C (fi) * 1968-07-15 1977-04-12 Rhone Poulenc Sa Menetelmä uusien kasvainten naftaseenijohdannaisten valmistamiseksi.
GB1467383A (en) * 1974-06-12 1977-03-16 Farmaceutici Italia Daunomycin analogues
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8759510B2 (en) 2008-06-11 2014-06-24 Gilead Pharmasset Llc Nucleoside cyclicphosphates
US8551973B2 (en) 2008-12-23 2013-10-08 Gilead Pharmasset Llc Nucleoside analogs
US8716262B2 (en) 2008-12-23 2014-05-06 Gilead Pharmasset Llc Nucleoside phosphoramidates
US8716263B2 (en) 2008-12-23 2014-05-06 Gilead Pharmasset Llc Synthesis of purine nucleosides
US8957045B2 (en) 2008-12-23 2015-02-17 Gilead Pharmasset Llc Nucleoside phosphoramidates
US9045520B2 (en) 2008-12-23 2015-06-02 Gilead Pharmasset Llc Synthesis of purine nucleosides
US8859756B2 (en) 2010-03-31 2014-10-14 Gilead Pharmasset Llc Stereoselective synthesis of phosphorus containing actives

Also Published As

Publication number Publication date
JPS532463A (en) 1978-01-11
GB1509875A (en) 1978-05-04
ATA450676A (de) 1977-12-15
NL175300B (nl) 1984-05-16
ATA636377A (de) 1978-01-15
SE7606808L (sv) 1977-12-16
CH622529A5 (en) 1981-04-15
NL930090I1 (nl) 1993-10-01
US4107423A (en) 1978-08-15
FR2355028A1 (fr) 1978-01-13
NL7606897A (nl) 1977-12-28
JPS6123200B2 (fr) 1986-06-04
SE8100471L (sv) 1981-01-26
NL175300C (nl) 1984-10-16
CA1046510A (fr) 1979-01-16
DE2626783C2 (de) 1985-08-14
SE421318B (sv) 1981-12-14
NL930090I2 (nl) 1994-03-16
SE447988B (sv) 1987-01-12
AT345461B (de) 1978-09-25
DE2626783A1 (de) 1977-12-29
AT344899B (de) 1978-08-10
FR2355028B3 (fr) 1979-03-02

Similar Documents

Publication Publication Date Title
BE842930A (fr) Procede de preparation d&#39;anthracyclines et d&#39;anthracyclinones optiquement actives
FR2320105A1 (fr) Daunomycines derivees d&#39;anthracyclinones optiquement actives et leur procede de preparation
BE856401A (fr) Procede de preparation de l&#39;ether methyl-t-butylique pur
BE865260A (fr) Procede de preparation d&#39;octafluoropropane
BE882424A (fr) Bac pour plantes
FR2342981A1 (fr) Procede de preparation d&#39;hydrogenosilanes
LU81482A1 (fr) Procede de preparation de d-camphorate de l-carnitinamide et de d-camphorate de d-carnitinamide
FR2321504A1 (fr) Procede de desoxygenation d&#39;alcools secondaires et application a la preparation d&#39;antibiotiques
BE858576A (fr) Procede de preparation d&#39;ethers
BE871850A (fr) Procede de preparation d&#39;alcool beta-phenyl-ethylique
BE855795A (fr) Procede de synthese d&#39;anthracyclinones optiquement actives
FR2353512A1 (fr) Procede de preparation d&#39;acetals
BE857370A (fr) Procede de preparation d&#39;amoxycilline sodique
PT66819B (fr) Procede de preparation de n-(1&#39;-allyl 2&#39;-pyrrolidylmethyl)2,3-dimethoxy 5-sulfamoyl benzamida et ses derives
FR2341529A1 (fr) Procede de preparation de b&#39;&#39;-a12o3
BE853940A (fr) 4,4&#39;-bis-formyl-polyhalo-diphenoxyalcanes procede de preparation et application a la synthese de 4,4-dicyanopolyhalodiphenoxyalcanes
FR2347337A1 (fr) Procede de preparation et de purification de la secretine
FR2343717A1 (fr) Procede de preparation de phenylglycine optiquement active
BE842845A (fr) Procede de preparation d&#39;indolo-quinolizines optiquement actives
FR2305412A1 (fr) Procede de preparation d&#39;a-phenylglycines optiquement actives et composes intermediaires dans ledit procede
BE856446A (fr) Procede de preparation d&#39;amoxycilline sodique
BE852496A (fr) Procede de preparation d&#39;o-hydroxyaldehydes et o-hydroxycetones aromatiques
BE855125A (fr) Procede de preparation d&#39;ethylene-glycol
BE854314A (fr) Procede de preparation de beta-halo-acetals et de beta-halo-cetals
BE855378A (fr) Procede de preparation d&#39;acetals

Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: SOCIETA FARMACEUTICI ITALIA S.P.A.

Effective date: 19960614