JPS532463A - Production of anthracycline compound - Google Patents
Production of anthracycline compoundInfo
- Publication number
- JPS532463A JPS532463A JP7454176A JP7454176A JPS532463A JP S532463 A JPS532463 A JP S532463A JP 7454176 A JP7454176 A JP 7454176A JP 7454176 A JP7454176 A JP 7454176A JP S532463 A JPS532463 A JP S532463A
- Authority
- JP
- Japan
- Prior art keywords
- production
- anthracycline compound
- anthracycline
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7617955A FR2355028A1 (fr) | 1976-06-14 | 1976-06-14 | Procede pour la preparation de glycosides derives d'anthracyclines optiquement actives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS532463A true JPS532463A (en) | 1978-01-11 |
JPS6123200B2 JPS6123200B2 (ja) | 1986-06-04 |
Family
ID=9174331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7454176A Granted JPS532463A (en) | 1976-06-14 | 1976-06-25 | Production of anthracycline compound |
Country Status (11)
Country | Link |
---|---|
US (1) | US4107423A (ja) |
JP (1) | JPS532463A (ja) |
AT (2) | AT345461B (ja) |
BE (1) | BE842930A (ja) |
CA (1) | CA1046510A (ja) |
CH (1) | CH622529A5 (ja) |
DE (1) | DE2626783C2 (ja) |
FR (1) | FR2355028A1 (ja) |
GB (1) | GB1509875A (ja) |
NL (2) | NL175300C (ja) |
SE (2) | SE421318B (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56135021A (en) * | 1980-03-25 | 1981-10-22 | Nippon Kokan Kk <Nkk> | Lining for internal surface of welded part of steel pipe |
JPH021423A (ja) * | 1988-02-12 | 1990-01-05 | Farmitalia Carlo Erba Spa | 4―デメトキシ―ダウノルビシンのアグリコンである4―デメトキシダウノマイシノンの製造方法 |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1567456A (en) * | 1976-11-16 | 1980-05-14 | Farmaceutici Italia | Daunomycin derivatives |
IL55431A (en) * | 1978-08-24 | 1982-07-30 | Yeda Res & Dev | Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them |
NL8001417A (nl) * | 1979-03-17 | 1980-09-19 | Erba Farmitalia | Antitumorglycosiden. |
GB2056443B (en) * | 1979-08-20 | 1984-01-18 | Hoffmann La Roche | Cyclic compounds |
CA1174669A (en) * | 1980-07-18 | 1984-09-18 | Michael J. Broadhurst | Anthracycline glycosides |
GB8317037D0 (en) * | 1983-06-23 | 1983-07-27 | Erba Farmitalia | 6-deoxyanthracyclines |
US4540695A (en) * | 1981-08-12 | 1985-09-10 | Sumitomo Chemical Co., Ltd. | Aminonaphthacene derivatives and their use |
NL8300150A (nl) * | 1982-01-26 | 1983-08-16 | Erba Farmitalia | Daunorubicine en doxorubicine-analoga, hun bereiding en toepassing. |
AT380480B (de) * | 1982-05-24 | 1986-05-26 | Erba Farmitalia | Verfahren zur herstellung von anthracyclinglykosiden |
JPS59212499A (ja) * | 1983-05-13 | 1984-12-01 | アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド | 抗腫瘍性抗生物質アントラサイクリンの4−デメトキシ−3′−デアミノ−3′(4−モリホリニル)誘導体 |
US4831019A (en) * | 1983-10-31 | 1989-05-16 | Adria Laboratories, Inc. | Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines |
US4496485A (en) * | 1983-11-25 | 1985-01-29 | G. D. Searle & Co. | Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones |
NZ224252A (en) * | 1987-04-21 | 1991-09-25 | Erba Carlo Spa | An anthracycline glycoside and its preparation |
GB9418260D0 (en) * | 1994-09-09 | 1994-10-26 | Erba Carlo Spa | Anthracycline derivatives |
DE10155016A1 (de) * | 2001-11-07 | 2003-05-15 | Knoell Hans Forschung Ev | Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung |
US8173621B2 (en) | 2008-06-11 | 2012-05-08 | Gilead Pharmasset Llc | Nucleoside cyclicphosphates |
CA2748057C (en) | 2008-12-23 | 2018-07-03 | Pharmasset, Inc. | Nucleoside phosphoramidates |
BRPI0922508A8 (pt) | 2008-12-23 | 2016-01-19 | Pharmasset Inc | Análogos de nucleosídeo |
JP5793084B2 (ja) | 2008-12-23 | 2015-10-14 | ギリアド ファーマセット エルエルシー | プリンヌクレオシドの合成 |
CN102858790A (zh) | 2010-03-31 | 2013-01-02 | 吉利德制药有限责任公司 | 核苷氨基磷酸酯 |
US8846882B2 (en) * | 2011-04-29 | 2014-09-30 | Synbias Pharma Ag | Method of producing 4-demethoxydaunorubicin |
CN104151376B (zh) * | 2014-06-23 | 2017-02-08 | 天津药物研究院新药评价有限公司 | 一种抗肿瘤药物及其合成方法和用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3427300A (en) * | 1965-11-12 | 1969-02-11 | Merck & Co Inc | Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds |
YU33730B (en) * | 1967-04-18 | 1978-02-28 | Farmaceutici Italia | Process for preparing a novel antibiotic substance and salts thereof |
US3803124A (en) * | 1968-04-12 | 1974-04-09 | Farmaceutici It Soc | Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives |
US3629231A (en) * | 1968-05-23 | 1971-12-21 | Biorex Laboratories Ltd | Derivatives of glycyrrhetinic acid |
FI51808C (fi) * | 1968-07-15 | 1977-04-12 | Rhone Poulenc Sa | Menetelmä uusien kasvainten naftaseenijohdannaisten valmistamiseksi. |
GB1467383A (en) * | 1974-06-12 | 1977-03-16 | Farmaceutici Italia | Daunomycin analogues |
US4039663A (en) * | 1975-03-19 | 1977-08-02 | Societa' Farmaceutici Italia S.P.A. | Daunomycins, process for their uses and intermediates |
-
1976
- 1976-06-12 GB GB24439/76A patent/GB1509875A/en not_active Expired
- 1976-06-14 BE BE167900A patent/BE842930A/xx not_active IP Right Cessation
- 1976-06-14 FR FR7617955A patent/FR2355028A1/fr active Granted
- 1976-06-15 DE DE2626783A patent/DE2626783C2/de not_active Expired
- 1976-06-15 SE SE7606808A patent/SE421318B/xx active Protection Beyond IP Right Term
- 1976-06-16 CH CH769276A patent/CH622529A5/de not_active IP Right Cessation
- 1976-06-21 AT AT636377A patent/AT345461B/de not_active IP Right Cessation
- 1976-06-21 AT AT450676A patent/AT344899B/de active Protection Beyond IP Right Term
- 1976-06-24 NL NLAANVRAGE7606897,A patent/NL175300C/xx not_active IP Right Cessation
- 1976-06-25 JP JP7454176A patent/JPS532463A/ja active Granted
- 1976-06-29 CA CA255,970A patent/CA1046510A/en not_active Expired
- 1976-08-14 US US05/695,434 patent/US4107423A/en not_active Expired - Lifetime
-
1981
- 1981-01-26 SE SE8100471A patent/SE447988B/sv unknown
-
1993
- 1993-06-24 NL NL930090C patent/NL930090I2/nl unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56135021A (en) * | 1980-03-25 | 1981-10-22 | Nippon Kokan Kk <Nkk> | Lining for internal surface of welded part of steel pipe |
JPH021423A (ja) * | 1988-02-12 | 1990-01-05 | Farmitalia Carlo Erba Spa | 4―デメトキシ―ダウノルビシンのアグリコンである4―デメトキシダウノマイシノンの製造方法 |
Also Published As
Publication number | Publication date |
---|---|
JPS6123200B2 (ja) | 1986-06-04 |
NL175300C (nl) | 1984-10-16 |
US4107423A (en) | 1978-08-15 |
AT344899B (de) | 1978-08-10 |
ATA450676A (de) | 1977-12-15 |
SE421318B (sv) | 1981-12-14 |
ATA636377A (de) | 1978-01-15 |
FR2355028A1 (fr) | 1978-01-13 |
CA1046510A (en) | 1979-01-16 |
NL930090I1 (nl) | 1993-10-01 |
NL175300B (nl) | 1984-05-16 |
AT345461B (de) | 1978-09-25 |
BE842930A (fr) | 1976-10-01 |
SE7606808L (sv) | 1977-12-16 |
CH622529A5 (en) | 1981-04-15 |
SE447988B (sv) | 1987-01-12 |
DE2626783A1 (de) | 1977-12-29 |
DE2626783C2 (de) | 1985-08-14 |
SE8100471L (sv) | 1981-01-26 |
GB1509875A (en) | 1978-05-04 |
NL7606897A (nl) | 1977-12-28 |
FR2355028B3 (ja) | 1979-03-02 |
NL930090I2 (nl) | 1994-03-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5388022A (en) | Manufacture of bitumennpolymer compound | |
JPS532463A (en) | Production of anthracycline compound | |
JPS5353690A (en) | Production of antiibacterial compound | |
JPS5315493A (en) | Production of androstann177 one derivative | |
JPS5332164A (en) | Production of icecreams | |
JPS5323994A (en) | Production of 33chlorcephlosporin | |
JPS5318578A (en) | Production of gammaa pylones | |
JPS5356654A (en) | Production of dichloroazetidinone | |
JPS5312894A (en) | Production of pyrazoloquinazolinone derivative | |
JPS5340735A (en) | Production of pentaapeptide | |
JPS6427487A (en) | Production of 1-desoxynodirimycin | |
GB1533200A (en) | Production of methyldichlorophosphane | |
JPS5315362A (en) | Production of steroid compound | |
JPS535194A (en) | Improved production of betaalactam | |
JPS535151A (en) | Production of 11alphaa hydroxycholestelol | |
JPS52108974A (en) | Production of triazolethiol | |
JPS5372896A (en) | Production of polylisine | |
JPS5331653A (en) | Production of betaa methylgigoxine | |
JPS52144686A (en) | Production of 33benzoazepine derivative | |
JPS52131594A (en) | Production of nnglycosyl derivative of polyenemacroride | |
JPS52105242A (en) | Production of instant sekihan | |
IL52194A0 (en) | Production of o o-dialkyl-phosphorochloridothionates | |
JPS539797A (en) | Production of pyrazolopyridotriazolopirimidine derivative | |
JPS5344571A (en) | Production of benzisoquinolinediones | |
JPS5332165A (en) | Production of icecake |