BE820542A - Nouveaux acides monoalkylamino-4-benzoiques - Google Patents
Nouveaux acides monoalkylamino-4-benzoiquesInfo
- Publication number
- BE820542A BE820542A BE149073A BE149073A BE820542A BE 820542 A BE820542 A BE 820542A BE 149073 A BE149073 A BE 149073A BE 149073 A BE149073 A BE 149073A BE 820542 A BE820542 A BE 820542A
- Authority
- BE
- Belgium
- Prior art keywords
- monoalkylamino
- new
- benzoic acids
- benzoic
- acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US402212A US3868416A (en) | 1973-10-01 | 1973-10-01 | Hypolipidemic 4-(monoalkylamino)benzoic acid derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BE820542A true BE820542A (fr) | 1975-04-01 |
Family
ID=23590998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE149073A BE820542A (fr) | 1973-10-01 | 1974-09-30 | Nouveaux acides monoalkylamino-4-benzoiques |
Country Status (22)
Country | Link |
---|---|
US (2) | US3868416A (fr) |
JP (1) | JPS5747901B2 (fr) |
AR (1) | AR211687A1 (fr) |
AT (1) | AT338250B (fr) |
BE (1) | BE820542A (fr) |
CA (1) | CA1077957A (fr) |
CH (1) | CH609676A5 (fr) |
DD (1) | DD116031A5 (fr) |
DE (1) | DE2446010C2 (fr) |
DK (1) | DK141844B (fr) |
ES (1) | ES430574A1 (fr) |
FR (1) | FR2246267B1 (fr) |
GB (1) | GB1488674A (fr) |
GT (1) | GT197851174A (fr) |
HU (1) | HU175875B (fr) |
IE (1) | IE40527B1 (fr) |
IL (1) | IL45643A (fr) |
NL (1) | NL179725C (fr) |
SE (1) | SE410595B (fr) |
SU (1) | SU590311A1 (fr) |
YU (1) | YU262274A (fr) |
ZA (1) | ZA745732B (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1471431A (en) * | 1974-04-30 | 1977-04-27 | Science Union & Cie | Alkanolamine derivatives processes for their preparation and pharmaceutical compositions containing them |
US4185115A (en) * | 1975-03-12 | 1980-01-22 | American Cyanamid Company | Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives |
US4350822A (en) * | 1975-03-12 | 1982-09-21 | American Cyanamid Company | Antilipidemicpara-[aryl(alkyl or alkenyl)amino]benzoic acid derivatives |
US4058550A (en) * | 1975-10-28 | 1977-11-15 | American Cyanamid Company | Polysubstituted-alkyl esters of 4-alkylaminobenzoic acids |
US4182776A (en) * | 1975-12-09 | 1980-01-08 | American Cyanamid Company | Method of treating lipidemia with aryloxyalkylaminobenzoic acids and esters |
AU500881B2 (en) * | 1976-01-19 | 1979-06-07 | Dow Chemical Company, The | Hypolipidemic p-aminobenzoic acids |
GB1576007A (en) * | 1976-02-11 | 1980-10-01 | Beecham Group Ltd | Hypolipidaemic compositions |
US4105791A (en) * | 1976-03-22 | 1978-08-08 | The Dow Chemical Company | Hypolipidemic cycloalkylaminobenzoic acids |
US4133890A (en) * | 1977-01-05 | 1979-01-09 | The Dow Chemical Company | Hypolipidemic compositions and method employing derivatives of 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid |
US4117158A (en) * | 1977-09-27 | 1978-09-26 | American Cyanamid Company | 4-(monoalkylamino)benzonitriles useful as anti-atherosclerotic agents |
US4245120A (en) * | 1977-09-27 | 1981-01-13 | American Cyanamid Company | 4-(Monoalkylamino)benzene polycarboxylic acids |
US4136256A (en) * | 1977-09-27 | 1979-01-23 | American Cyanamid Company | 4-(monoalkylamino)benzoic acid imidates |
US4245119A (en) * | 1977-09-27 | 1981-01-13 | American Cyanamid Company | 4-(Monoalkylamino) benzene polycarboxylic acids |
US4242273A (en) * | 1977-09-27 | 1980-12-30 | American Cyanamid Company | 4-(Monoalkylamino)benzoic acid amides and imidates |
US4154756A (en) * | 1977-12-15 | 1979-05-15 | American Cyanamid Company | 2-Substituted-4'-(monoalkylamino)-acetophenones |
US4348399A (en) * | 1978-02-02 | 1982-09-07 | American Cyanamid Company | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives |
US4272546A (en) * | 1977-12-19 | 1981-06-09 | American Cyanamid Company | Esters of 4-(monoalkylamino)benzoic hydroxyalkanoic acids |
US4254138A (en) * | 1977-12-19 | 1981-03-03 | American Cyanamid Company | Esters of 4-(monoalkylamino)benzoic hydroxyalkanoic acids |
US4333940A (en) * | 1978-02-02 | 1982-06-08 | American Cyanamid Company | Ring-fluorinated 4-(monosubstituted-amino) phenyl compounds in inhibiting atherosclerotic lesion development |
US4230628A (en) * | 1978-04-12 | 1980-10-28 | American Cyanamid Company | 4-[(Carboxyl- and sulfamyl-substituted alkyl)-amino] benzoic acids and analogs |
US4205085A (en) * | 1978-03-09 | 1980-05-27 | American Cyanamid Company | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino)phenyl compounds |
US4245097A (en) * | 1978-02-27 | 1981-01-13 | American Cyanamid Company | 4-[(Monosubstituted-alkyl) amino] benzoic acids and analogs as hypolipidemic and antiatherosclerotic agents |
IL56517A0 (en) * | 1978-02-02 | 1979-03-12 | American Cyanamid Co | Novel 4-(cycloalkyl or cyclalkenyl substituted) amino, alkylamino or alkenylamino benzoic acids, salts and derivatives |
US4230878A (en) * | 1978-03-08 | 1980-10-28 | American Cyanamid Company | Hypolipidemic and antiatherosclerotic 4-[(cyclopropyl alkyl)amino]benzoic acids and derivatives |
US4243609A (en) * | 1978-02-02 | 1981-01-06 | American Cyanamid Company | Ring-fluorinated 4-(hexadecyl-amino) N-substituted benzamide compounds |
US4311846A (en) * | 1978-02-27 | 1982-01-19 | American Cyanamid Company | 4-[(Monosubstituted-alkyl) amino]benzoic acids and analogs as hypolipidemic and antiatherosclerotic agents |
US4178385A (en) * | 1978-03-03 | 1979-12-11 | The Dow Chemical Company | Method for treating hyperlipidemia in primates using 4-((4-fluorophenylmethyl)amino)benzoic acid |
US4310545A (en) * | 1978-03-09 | 1982-01-12 | American Cyanamid Company | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino) phenyl compounds |
US4318914A (en) * | 1978-03-09 | 1982-03-09 | American Cyanamid Company | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds |
US4305959A (en) * | 1978-03-09 | 1981-12-15 | American Cyanamid Company | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds |
US4307113A (en) * | 1978-04-20 | 1981-12-22 | Sandoz, Inc. | Anthranilic acid derivatives |
US4181737A (en) * | 1978-05-18 | 1980-01-01 | The Dow Chemical Company | 4-((3-Methoxyphenyl)amino)benzoic acid, a method for treating hyperlipidemia, and compositions thereof |
US4206223A (en) * | 1979-01-05 | 1980-06-03 | The Dow Chemical Company | Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof |
US4281019A (en) * | 1979-02-01 | 1981-07-28 | American Cyanamid Company | 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents |
YU57979A (en) * | 1979-03-09 | 1982-10-31 | Lek Tovarna Farmacevtskih | Process for preparing 4-9n-hexadecylamino0-benzoic acid |
US4263320A (en) * | 1979-06-04 | 1981-04-21 | The Dow Chemical Company | Hypoglycemic phenylpropynylamino benzoic acids |
US4311694A (en) * | 1979-12-31 | 1982-01-19 | American Cyanamid Company | Amorphous coprecipitates of 4-(monoalkylamino) benzoic acid and derivatives and certain water-soluble materials |
US4375478A (en) * | 1982-03-02 | 1983-03-01 | Abbott Laboratories | Aminobenzoic acid derivatives |
JP2659488B2 (ja) * | 1992-01-22 | 1997-09-30 | 川崎重工業株式会社 | 引戸装置 |
US20080045573A1 (en) * | 1993-09-20 | 2008-02-21 | Bova David J | Methods and Sustained Release Nicotinic Acid Compositions for Treating Hyperlipidemia |
US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
US6129930A (en) * | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
US6676967B1 (en) | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
US6080428A (en) * | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3758561A (en) * | 1968-10-18 | 1973-09-11 | Merck & Co Inc | 2-loweralkylamino-4-amino benzoic acids, their salts and esters, and acid addition salts thereof |
US3716644A (en) * | 1971-07-15 | 1973-02-13 | American Cyanamid Co | Hypolipidemic agents |
-
1973
- 1973-10-01 US US402212A patent/US3868416A/en not_active Expired - Lifetime
-
1974
- 1974-09-09 ZA ZA00745732A patent/ZA745732B/xx unknown
- 1974-09-11 IL IL45643A patent/IL45643A/xx unknown
- 1974-09-17 GB GB40539/74A patent/GB1488674A/en not_active Expired
- 1974-09-23 AR AR255678A patent/AR211687A1/es active
- 1974-09-26 DE DE2446010A patent/DE2446010C2/de not_active Expired
- 1974-09-27 IE IE2015/74A patent/IE40527B1/xx unknown
- 1974-09-27 YU YU02622/74A patent/YU262274A/xx unknown
- 1974-09-30 SE SE7412307A patent/SE410595B/xx not_active IP Right Cessation
- 1974-09-30 FR FR7432894A patent/FR2246267B1/fr not_active Expired
- 1974-09-30 BE BE149073A patent/BE820542A/fr not_active IP Right Cessation
- 1974-09-30 CA CA210,303A patent/CA1077957A/fr not_active Expired
- 1974-09-30 DK DK515474AA patent/DK141844B/da not_active IP Right Cessation
- 1974-10-01 SU SU742065154A patent/SU590311A1/ru active
- 1974-10-01 NL NLAANVRAGE7412956,A patent/NL179725C/xx not_active IP Right Cessation
- 1974-10-01 DD DD181444A patent/DD116031A5/xx unknown
- 1974-10-01 AT AT788574A patent/AT338250B/de not_active IP Right Cessation
- 1974-10-01 CH CH1321774A patent/CH609676A5/xx not_active IP Right Cessation
- 1974-10-01 JP JP49113271A patent/JPS5747901B2/ja not_active Expired
- 1974-10-01 HU HU74AE427A patent/HU175875B/hu unknown
- 1974-10-02 ES ES430574A patent/ES430574A1/es not_active Expired
- 1974-10-25 US US518022A patent/US3924001A/en not_active Expired - Lifetime
-
1978
- 1978-03-01 GT GT197851174A patent/GT197851174A/es unknown
Also Published As
Publication number | Publication date |
---|---|
HU175875B (en) | 1980-11-28 |
DK515474A (fr) | 1975-06-09 |
NL179725B (nl) | 1986-06-02 |
CH609676A5 (fr) | 1979-03-15 |
DK141844C (fr) | 1980-11-10 |
AR211687A1 (es) | 1978-02-28 |
GB1488674A (en) | 1977-10-12 |
DE2446010C2 (de) | 1985-05-15 |
ES430574A1 (es) | 1977-02-16 |
JPS5747901B2 (fr) | 1982-10-13 |
DE2446010A1 (de) | 1975-04-03 |
SU590311A1 (ru) | 1978-01-30 |
CA1077957A (fr) | 1980-05-20 |
NL7412956A (nl) | 1975-04-03 |
DK141844B (da) | 1980-06-30 |
NL179725C (nl) | 1986-11-03 |
GT197851174A (es) | 1979-08-23 |
YU262274A (en) | 1982-02-25 |
SE410595B (sv) | 1979-10-22 |
AT338250B (de) | 1977-08-10 |
DD116031A5 (fr) | 1975-11-05 |
IE40527B1 (en) | 1979-06-20 |
IL45643A0 (en) | 1974-11-29 |
SE7412307L (fr) | 1975-04-02 |
IL45643A (en) | 1979-09-30 |
US3924001A (en) | 1975-12-02 |
US3868416A (en) | 1975-02-25 |
FR2246267B1 (fr) | 1977-10-28 |
FR2246267A1 (fr) | 1975-05-02 |
ATA788574A (de) | 1976-12-15 |
JPS5059347A (fr) | 1975-05-22 |
IE40527L (en) | 1975-04-01 |
ZA745732B (en) | 1975-09-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: AMERICAN CYANAMID CY Effective date: 19880930 |