BE801587A - Arginine and lysine salts of cephalosphorin - from cephalosporanic acid with arginine or lysine, have reduced side effects - Google Patents
Arginine and lysine salts of cephalosphorin - from cephalosporanic acid with arginine or lysine, have reduced side effectsInfo
- Publication number
- BE801587A BE801587A BE132835A BE132835A BE801587A BE 801587 A BE801587 A BE 801587A BE 132835 A BE132835 A BE 132835A BE 132835 A BE132835 A BE 132835A BE 801587 A BE801587 A BE 801587A
- Authority
- BE
- Belgium
- Prior art keywords
- arginine
- lysine
- salts
- cephalosporanic acid
- cephalosphorin
- Prior art date
Links
- 239000004475 Arginine Substances 0.000 title abstract 4
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 title abstract 4
- 239000004472 Lysine Substances 0.000 title abstract 3
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title abstract 3
- YGBFLZPYDUKSPT-MRVPVSSYSA-N cephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C[C@H]21 YGBFLZPYDUKSPT-MRVPVSSYSA-N 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 title 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical class NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 title 1
- -1 phenoxy, 1-cyclohexenyl Chemical group 0.000 abstract 6
- 125000000066 S-methyl group Chemical group [H]C([H])([H])S* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000005344 pyridylmethyl group Chemical group [H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])* 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
- 230000008961 swelling Effects 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47066076A JPS4925118A (cg-RX-API-DMAC7.html) | 1972-06-30 | 1972-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE801587A true BE801587A (en) | 1973-12-28 |
Family
ID=13305378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE132835A BE801587A (en) | 1972-06-30 | 1973-06-28 | Arginine and lysine salts of cephalosphorin - from cephalosporanic acid with arginine or lysine, have reduced side effects |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS4925118A (cg-RX-API-DMAC7.html) |
| BE (1) | BE801587A (cg-RX-API-DMAC7.html) |
| SE (1) | SE402917B (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2600635B1 (fr) * | 1986-06-26 | 1989-09-08 | Comalco Alu | Procede pour la production de matieres utiles y compris de la nepheline synthetique a partir des boues rouges du procede bayer |
| BR112018073667A2 (pt) * | 2016-05-16 | 2019-03-12 | Pulmagen Therapeutics (Asthma) Limited | cristal de derivado de quinolina |
-
1972
- 1972-06-30 JP JP47066076A patent/JPS4925118A/ja active Pending
-
1973
- 1973-06-28 SE SE7309137A patent/SE402917B/xx unknown
- 1973-06-28 BE BE132835A patent/BE801587A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4925118A (cg-RX-API-DMAC7.html) | 1974-03-06 |
| SE402917B (sv) | 1978-07-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE34568B1 (en) | Oxa- and thia-diazole derivatives | |
| BE801587A (en) | Arginine and lysine salts of cephalosphorin - from cephalosporanic acid with arginine or lysine, have reduced side effects | |
| GB1289358A (cg-RX-API-DMAC7.html) | ||
| BE804144A (en) | H-2-Receptor antihistamines esp gastric acid inhibitors - -N-cyano-N"-(heterocyclyl-alkyl-(thio oxa amino or methylene-alkyl)-guanidines | |
| GB1327510A (en) | Esters of mandeloylaminocephalosporanic acids | |
| GB1429539A (en) | Derivatives of penam-3-carboxylic acid and cephem-4-carboxylic acid and processes for their manufacture | |
| GB1432925A (en) | 7-alpha-cyanomethylaryl-acetamide-cephalosporins | |
| GB1284227A (en) | Penicillin and cephalosporin derivatives | |
| GB1430293A (en) | Cephalosporin derivatives | |
| GB1474738A (en) | Cephalosporanic acid derivatives the preparation thereof and pharmaceutical compositions containing them | |
| GB1454589A (en) | 7-trichloroacetamido-3-desacetoxy-cephalosporanic acid derivatives their preparation and use | |
| IE39373B1 (en) | 3-substituted ethyl-cephalosporin compounds | |
| GB1040166A (en) | Penicillins | |
| FR2074731A1 (en) | Oxazoles prepn - by heating nitriles with ketones alpha-substituted with a reactive group | |
| GB1061335A (en) | Penicillins | |
| GB1398564A (en) | 1-amino substituted-1-cycloalkane derivatives of 6-amino penicillanic acid | |
| FR2336932A2 (fr) | Derives pyridiniques, leur preparation et leurs applications | |
| GB1457498A (en) | Pharmaceutical composition for the treatment of hydropic conditions | |
| FR2191882A1 (en) | Antibacterial 6-acyl APA cpds - 6-(2-(thienyloxycarbonyl)-2-(hetero)aryl-acetamido) Penicillanic acids | |
| GB1481808A (en) | Cepham derivatives and preparation thereof | |
| GB1408831A (en) | Hydroxymethylamino nitrile salts for quenching the fluorescence of optical brightening agents | |
| GB1307450A (en) | Penicillins | |
| FR2375240A1 (fr) | Nouveaux antibiotiques du type b-lactame, leur procede de preparation et medicament les contenant | |
| IE37961B1 (en) | 6-(alpha-(amidino-and imidoylaminoalkanoylamino)penicillanic acids | |
| GB1179856A (en) | Thiazolyl Penicillins and their Preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE20 | Patent expired |
Owner name: TAKEDA CHEMICAL INDUSTRIES LTD Effective date: 19930628 |