BE801079A - 2-(heteroaryl-methyl)-5,9 beta-dialcoyl-6,7-benzomorphanes et leurs sels d'addition avec des acides - Google Patents

2-(heteroaryl-methyl)-5,9 beta-dialcoyl-6,7-benzomorphanes et leurs sels d'addition avec des acides

Info

Publication number
BE801079A
BE801079A BE132406A BE132406A BE801079A BE 801079 A BE801079 A BE 801079A BE 132406 A BE132406 A BE 132406A BE 132406 A BE132406 A BE 132406A BE 801079 A BE801079 A BE 801079A
Authority
BE
Belgium
Prior art keywords
dialcoyl
benzomorphanes
heteroaryl
beta
acids
Prior art date
Application number
BE132406A
Other languages
English (en)
French (fr)
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of BE801079A publication Critical patent/BE801079A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
BE132406A 1972-06-19 1973-06-18 2-(heteroaryl-methyl)-5,9 beta-dialcoyl-6,7-benzomorphanes et leurs sels d'addition avec des acides BE801079A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2229695A DE2229695A1 (de) 1972-06-19 1972-06-19 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BE801079A true BE801079A (fr) 1973-12-18

Family

ID=5848060

Family Applications (1)

Application Number Title Priority Date Filing Date
BE132406A BE801079A (fr) 1972-06-19 1973-06-18 2-(heteroaryl-methyl)-5,9 beta-dialcoyl-6,7-benzomorphanes et leurs sels d'addition avec des acides

Country Status (13)

Country Link
US (1) US3931194A (pm)
JP (1) JPS5711908B2 (pm)
AT (6) AT329200B (pm)
BE (1) BE801079A (pm)
CH (9) CH589649A5 (pm)
DE (1) DE2229695A1 (pm)
DK (1) DK136904C (pm)
ES (8) ES416037A1 (pm)
FR (1) FR2189056B1 (pm)
GB (1) GB1433817A (pm)
NL (1) NL7308483A (pm)
NO (1) NO137694C (pm)
SE (1) SE405121B (pm)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
JPS63177704A (ja) * 1987-01-16 1988-07-21 松山株式会社 農作業機連結装置
WO2009017664A1 (en) 2007-07-26 2009-02-05 Vitae Pharmaceuticals, Inc. CYCLIC INHIBITORS OF 11β-HYDROXYSTERIOD DEHYDROGENASE 1
AR069545A1 (es) * 2007-11-16 2010-02-03 Boehringer Ingelheim Pharma Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
EP2252601B1 (en) 2008-01-24 2012-12-19 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2245014B1 (en) * 2008-02-12 2011-11-02 Boehringer Ingelheim International GmbH Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
JP5730021B2 (ja) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体
US8138178B2 (en) 2008-05-01 2012-03-20 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5696037B2 (ja) 2008-05-01 2015-04-08 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
EP2324017B1 (en) 2008-07-25 2014-12-31 Boehringer Ingelheim International GmbH INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
PE20110566A1 (es) 2008-07-25 2011-09-02 Boehringer Ingelheim Int Inhibidores ciclicos de 11beta-hidroxiesteroide deshidrogenasa 1
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
WO2011159760A1 (en) 2010-06-16 2011-12-22 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
EP2744783A1 (en) 2011-08-17 2014-06-25 Boehringer Ingelheim International GmbH Indenopyridine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (pm) * 1958-09-22
FR1281227A (fr) * 1958-09-22 1962-01-12 Smith Kline French Lab Perfectionnements apportés aux procédés pour la préparation de dérivés d'aralcoylbenzomorphane
CS166803B2 (pm) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
SE392895B (sv) * 1971-08-24 1977-04-25 Sumitomo Chemical Co Forfarande for framstellning av bensomorfanderivat och deras salter

Also Published As

Publication number Publication date
FR2189056B1 (pm) 1976-10-22
CH582698A5 (pm) 1976-12-15
DK136904C (da) 1978-06-26
CH583228A5 (pm) 1976-12-31
FR2189056A1 (pm) 1974-01-25
ES431515A1 (es) 1976-11-01
ES431511A1 (es) 1976-11-01
ES431512A1 (es) 1976-11-01
ES431513A1 (es) 1976-11-01
NO137694C (no) 1978-04-05
NO137694B (no) 1977-12-27
AT329200B (de) 1976-04-26
CH589648A5 (pm) 1977-07-15
JPS5711908B2 (pm) 1982-03-08
AU5704673A (en) 1974-12-19
ES431510A1 (es) 1976-11-01
JPS4961170A (pm) 1974-06-13
ATA489874A (de) 1975-07-15
CH583231A5 (pm) 1976-12-31
ES416037A1 (es) 1976-02-16
NL7308483A (pm) 1973-12-21
ATA490074A (de) 1975-06-15
AT325218B (de) 1975-10-10
DK136904B (da) 1977-12-12
ATA489774A (de) 1975-06-15
AT328628B (de) 1976-03-25
CH589649A5 (pm) 1977-07-15
AT329199B (de) 1976-04-26
GB1433817A (en) 1976-04-28
AT328629B (de) 1976-03-25
SE405121B (sv) 1978-11-20
CH582697A5 (pm) 1976-12-15
ES431514A1 (es) 1976-11-01
AT328627B (de) 1976-03-25
DE2229695A1 (de) 1974-01-31
CH583229A5 (pm) 1976-12-31
ATA489474A (de) 1975-06-15
ATA489974A (de) 1975-07-15
CH583230A5 (pm) 1976-12-31
ES431516A1 (es) 1976-11-16
CH583227A5 (pm) 1976-12-31
US3931194A (en) 1976-01-06

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