BE783499A - N-tertiaire aminomethyl-4' dibenzo (b,e) oxepine-11-spiro- 2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutique - Google Patents
N-tertiaire aminomethyl-4' dibenzo (b,e) oxepine-11-spiro- 2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutiqueInfo
- Publication number
- BE783499A BE783499A BE783499A BE783499A BE783499A BE 783499 A BE783499 A BE 783499A BE 783499 A BE783499 A BE 783499A BE 783499 A BE783499 A BE 783499A BE 783499 A BE783499 A BE 783499A
- Authority
- BE
- Belgium
- Prior art keywords
- dioxolanne
- tertiaire
- oxepine
- dibenzo
- aminomethyl
- Prior art date
Links
- UZVGSSNIUNSOFA-UHFFFAOYSA-N dibenzofuran-1-carboxylic acid Chemical compound O1C2=CC=CC=C2C2=C1C=CC=C2C(=O)O UZVGSSNIUNSOFA-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7119501A FR2139651A1 (en) | 1971-05-28 | 1971-05-28 | 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch |
| FR7210250A FR2176561A2 (en) | 1972-03-23 | 1972-03-23 | 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE783499A true BE783499A (fr) | 1972-11-16 |
Family
ID=26216420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE783499A BE783499A (fr) | 1971-05-28 | 1972-05-15 | N-tertiaire aminomethyl-4' dibenzo (b,e) oxepine-11-spiro- 2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutique |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3845046A (cs) |
| JP (1) | JPS5218196B1 (cs) |
| AR (1) | AR192786A1 (cs) |
| AU (1) | AU465949B2 (cs) |
| BE (1) | BE783499A (cs) |
| CA (1) | CA989404A (cs) |
| CH (1) | CH532034A (cs) |
| CS (1) | CS181224B2 (cs) |
| DE (1) | DE2225245C3 (cs) |
| GB (1) | GB1359951A (cs) |
| IL (1) | IL39496A (cs) |
| IT (1) | IT1052682B (cs) |
| LU (1) | LU65380A1 (cs) |
| NL (1) | NL7207229A (cs) |
| SE (1) | SE373583B (cs) |
| SU (1) | SU420174A3 (cs) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4048164A (en) * | 1971-06-18 | 1977-09-13 | Delalande S.A. | N'-substituted derivatives of 4'-(N-piperazinylmethyl)spiro dibenzocycloheptadi- (or tri-) ene-5,2'-dioxolane(1',3') |
| EP0295209A3 (de) * | 1987-06-10 | 1990-01-24 | Ciba-Geigy Ag | Orthokohlensäureester |
| US6262047B1 (en) | 1996-10-11 | 2001-07-17 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6194435B1 (en) | 1996-10-11 | 2001-02-27 | Cor Therapeutics, Inc. | Lactams as selective factor Xa inhibitors |
| US6369080B2 (en) | 1996-10-11 | 2002-04-09 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6063794A (en) * | 1996-10-11 | 2000-05-16 | Cor Therapeutics Inc. | Selective factor Xa inhibitors |
| JP2001523226A (ja) | 1997-04-14 | 2001-11-20 | シーオーアール セラピューティクス インコーポレイテッド | 選択的Ｘａ因子阻害剤 |
| NZ500354A (en) * | 1997-04-14 | 2001-11-30 | Cor Therapeutics Inc | Cyclic diaza compounds as selective factor Xa inhibitors for treating thrombotic related disorders |
| AU6896398A (en) | 1997-04-14 | 1998-11-11 | Cor Therapeutics, Inc. | Selective factor xa inhibitors |
| WO1998046628A1 (en) * | 1997-04-14 | 1998-10-22 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
| US6218382B1 (en) | 1997-08-11 | 2001-04-17 | Cor Therapeutics, Inc | Selective factor Xa inhibitors |
| US6333321B1 (en) | 1997-08-11 | 2001-12-25 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6228854B1 (en) | 1997-08-11 | 2001-05-08 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| JPWO2004087131A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 鎮咳剤 |
-
1972
- 1972-05-15 BE BE783499A patent/BE783499A/xx unknown
- 1972-05-17 LU LU65380A patent/LU65380A1/xx unknown
- 1972-05-22 IL IL39496A patent/IL39496A/xx unknown
- 1972-05-22 GB GB2391572A patent/GB1359951A/en not_active Expired
- 1972-05-23 CH CH757472A patent/CH532034A/fr not_active IP Right Cessation
- 1972-05-24 DE DE2225245A patent/DE2225245C3/de not_active Expired
- 1972-05-25 US US00256655A patent/US3845046A/en not_active Expired - Lifetime
- 1972-05-26 AR AR242209A patent/AR192786A1/es active
- 1972-05-26 SU SU1788862A patent/SU420174A3/ru active
- 1972-05-26 SE SE7206954A patent/SE373583B/xx unknown
- 1972-05-26 CS CS7200003650A patent/CS181224B2/cs unknown
- 1972-05-26 AU AU42788/72A patent/AU465949B2/en not_active Expired
- 1972-05-26 CA CA143,363A patent/CA989404A/fr not_active Expired
- 1972-05-27 IT IT68696/72A patent/IT1052682B/it active
- 1972-05-29 JP JP47052583A patent/JPS5218196B1/ja active Pending
- 1972-05-29 NL NL7207229A patent/NL7207229A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB1359951A (en) | 1974-07-17 |
| IL39496A0 (en) | 1972-07-26 |
| CH532034A (fr) | 1972-12-31 |
| JPS5218196B1 (cs) | 1977-05-20 |
| LU65380A1 (cs) | 1973-01-22 |
| CA989404A (fr) | 1976-05-18 |
| US3845046A (en) | 1974-10-29 |
| AR192786A1 (es) | 1973-03-14 |
| CS181224B2 (en) | 1978-03-31 |
| AU4278872A (en) | 1973-11-29 |
| DE2225245B2 (de) | 1978-03-02 |
| DE2225245C3 (de) | 1978-11-02 |
| NL7207229A (cs) | 1972-11-30 |
| SE373583B (sv) | 1975-02-10 |
| SU420174A3 (ru) | 1974-03-15 |
| AU465949B2 (en) | 1975-10-09 |
| IT1052682B (it) | 1981-07-20 |
| DE2225245A1 (de) | 1973-01-04 |
| IL39496A (en) | 1975-04-25 |
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