BE779058A - 2-(furylmethyl)6,7-benzomorphanes, leurs sels d'addition avec des acides et leurs procedes de fabrication - Google Patents
2-(furylmethyl)6,7-benzomorphanes, leurs sels d'addition avec des acides et leurs procedes de fabricationInfo
- Publication number
- BE779058A BE779058A BE779058A BE779058A BE779058A BE 779058 A BE779058 A BE 779058A BE 779058 A BE779058 A BE 779058A BE 779058 A BE779058 A BE 779058A BE 779058 A BE779058 A BE 779058A
- Authority
- BE
- Belgium
- Prior art keywords
- benzomorphanes
- furylmethyl
- acids
- manufacturing
- additional salts
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2105743A DE2105743C3 (de) | 1971-02-08 | 1971-02-08 | 2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung |
| DE19712108954 DE2108954A1 (en) | 1971-02-25 | 1971-02-25 | 2-(furylmethyl)-6,7-benzomorphans - useful as cns active agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE779058A true BE779058A (fr) | 1972-08-07 |
Family
ID=25760626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE779058A BE779058A (fr) | 1971-02-08 | 1972-02-07 | 2-(furylmethyl)6,7-benzomorphanes, leurs sels d'addition avec des acides et leurs procedes de fabrication |
Country Status (25)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2229695A1 (de) * | 1972-06-19 | 1974-01-31 | Boehringer Sohn Ingelheim | 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung |
| US4010164A (en) * | 1973-03-28 | 1977-03-01 | Boehringer Ingelheim Gmbh | N-(furyl-methyl)-2-hydroxy-5,9,9-trimethyl-benzomorphans and salts thereof |
| SU510999A3 (ru) * | 1973-10-27 | 1976-04-15 | К.Х.Берингер Зон, (Фирма) | Способ получени (метоксиметил-фурилметил)6,7-бензоморфанов илиморфинанов |
| US4087532A (en) * | 1974-03-09 | 1978-05-02 | Boehringer Ingelheim Gmbh | Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof |
| DE2437610A1 (de) * | 1974-08-05 | 1976-02-26 | Boehringer Sohn Ingelheim | Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung |
| GB1575009A (en) * | 1976-06-21 | 1980-09-17 | Acf Chemiefarma Nv | 6,7-benzomorphan derivatives |
| DE2716687A1 (de) * | 1977-04-15 | 1978-10-19 | Boehringer Sohn Ingelheim | 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel |
| DE3839659A1 (de) * | 1988-11-24 | 1990-05-31 | Boehringer Ingelheim Kg | Verwendung von benzomorphanen zur zytoprotektion |
| AR069545A1 (es) * | 2007-11-16 | 2010-02-03 | Boehringer Ingelheim Pharma | Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y |
| EP2245014B1 (en) * | 2008-02-12 | 2011-11-02 | Boehringer Ingelheim International GmbH | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| TW200950780A (en) | 2008-05-13 | 2009-12-16 | Boehringer Ingelheim Int | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| WO2013025664A1 (en) | 2011-08-17 | 2013-02-21 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1281227A (fr) * | 1958-09-22 | 1962-01-12 | Smith Kline French Lab | Perfectionnements apportés aux procédés pour la préparation de dérivés d'aralcoylbenzomorphane |
| FR1538362A (fr) * | 1966-05-20 | 1968-09-06 | Merck & Co Inc | Dérivés du benzomorphane |
-
1972
- 1972-01-26 CS CS483A patent/CS166801B2/cs unknown
- 1972-01-26 CS CS7061*A patent/CS166804B2/cs unknown
- 1972-01-26 CS CS7060*A patent/CS166803B2/cs unknown
- 1972-01-26 CS CS7059*A patent/CS166802B2/cs unknown
- 1972-02-01 US US00222669A patent/US3823150A/en not_active Expired - Lifetime
- 1972-02-03 CH CH158472A patent/CH573933A5/xx not_active IP Right Cessation
- 1972-02-03 CH CH1565575A patent/CH573935A5/xx not_active IP Right Cessation
- 1972-02-03 CH CH1565475A patent/CH574442A5/xx not_active IP Right Cessation
- 1972-02-03 CH CH1565375A patent/CH573934A5/xx not_active IP Right Cessation
- 1972-02-04 JP JP1276272A patent/JPS5545555B1/ja active Pending
- 1972-02-04 SU SU1918909A patent/SU469246A3/ru active
- 1972-02-04 SU SU1918905A patent/SU467519A3/ru active
- 1972-02-04 SU SU1918908A patent/SU479290A3/ru active
- 1972-02-04 SU SU1744912A patent/SU421187A3/ru active
- 1972-02-05 BG BG22164A patent/BG19600A3/xx unknown
- 1972-02-05 BG BG19654A patent/BG19800A3/xx unknown
- 1972-02-05 BG BG22165A patent/BG20792A3/xx unknown
- 1972-02-07 FI FI327/72A patent/FI57758C/fi active
- 1972-02-07 CA CA134,023A patent/CA969938A/en not_active Expired
- 1972-02-07 GB GB559472A patent/GB1384115A/en not_active Expired
- 1972-02-07 DD DD160731A patent/DD95847A5/xx unknown
- 1972-02-07 SE SE01397/72A patent/SE363630B/xx unknown
- 1972-02-07 AT AT168773A patent/AT318602B/de not_active IP Right Cessation
- 1972-02-07 NO NO325/72*[A patent/NO134054C/no unknown
- 1972-02-07 IL IL38699A patent/IL38699A/xx unknown
- 1972-02-07 NL NLAANVRAGE7201551,A patent/NL171898C/xx not_active IP Right Cessation
- 1972-02-07 AT AT168673A patent/AT318601B/de not_active IP Right Cessation
- 1972-02-07 BE BE779058A patent/BE779058A/xx not_active IP Right Cessation
- 1972-02-07 YU YU1657/72A patent/YU35016B/xx unknown
- 1972-02-07 PL PL1972153362A patent/PL78312B1/pl unknown
- 1972-02-07 AT AT96272A patent/AT312587B/de active
- 1972-02-07 YU YU00279/72A patent/YU27972A/xx unknown
- 1972-02-07 DK DK53372AA patent/DK129127B/da not_active IP Right Cessation
- 1972-02-07 ES ES399536A patent/ES399536A1/es not_active Expired
- 1972-02-08 RO RO72543A patent/RO59193A/ro unknown
- 1972-02-08 HU HUBO1349A patent/HU162946B/hu unknown
- 1972-02-08 FR FR7204151A patent/FR2124564B1/fr not_active Expired
- 1972-02-08 RO RO72541A patent/RO59251A/ro unknown
- 1972-02-08 PH PH13256A patent/PH10743A/en unknown
- 1972-02-08 IE IE156/72A patent/IE36071B1/xx unknown
- 1972-02-08 RO RO72542A patent/RO59165A/ro unknown
- 1972-02-08 RO RO69695A patent/RO58981A/ro unknown
- 1972-05-09 PL PL1972155268A patent/PL84115B3/pl unknown
- 1972-10-17 RO RO7200080094A patent/RO63052A/ro unknown
- 1972-11-04 ES ES408276A patent/ES408276A1/es not_active Expired
- 1972-11-04 ES ES408275A patent/ES408275A1/es not_active Expired
- 1972-11-04 ES ES408274A patent/ES408274A1/es not_active Expired
-
1978
- 1978-07-18 YU YU1720/78A patent/YU35255B/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: C.H. BOEHRINGER SOHN Effective date: 19890228 |