BE511318A

BE511318A -

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Publication number: BE511318A
Authority: BE; Belgium
Prior art keywords: sep; antibiotic; water; acid; culture
Prior art date

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English (en)

French (fr)

Publication of BE511318A publication Critical patent/BE511318A/fr

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230000003115 biocidal Effects 0.000 claims description 87
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 53
QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 42
239000002609 media Substances 0.000 claims description 42
HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 36
OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 32
XEKOWRVHYACXOJ-UHFFFAOYSA-N acetic acid ethyl ester Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 27
241000187747 Streptomyces Species 0.000 claims description 24
OKTJSMMVPCPJKN-UHFFFAOYSA-N carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 22
LRHPLDYGYMQRHN-UHFFFAOYSA-N n-butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 22
239000001963 growth media Substances 0.000 claims description 19
239000000243 solution Substances 0.000 claims description 18
VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 16
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239000002253 acid Substances 0.000 claims description 14
239000011780 sodium chloride Substances 0.000 claims description 14
238000000034 method Methods 0.000 claims description 12
IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 12
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RTZKZFJDLAIYFH-UHFFFAOYSA-N diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 11
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LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
-1 monosubstituted guanidines Chemical class 0.000 claims description 8
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NOQGLDMVAMRUJL-UHFFFAOYSA-N ON=NC1(S(O)(=O)=O)CC=CC=C1 Chemical compound ON=NC1(S(O)(=O)=O)CC=CC=C1 NOQGLDMVAMRUJL-UHFFFAOYSA-N 0.000 claims description 4
OXNIZHLAWKMVMX-UHFFFAOYSA-N Picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 claims description 4
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230000015572 biosynthetic process Effects 0.000 claims description 3
239000003795 chemical substances by application Substances 0.000 claims description 3
238000005755 formation reaction Methods 0.000 claims description 3
125000001769 aryl amino group Chemical group 0.000 claims description 2
150000001720 carbohydrates Chemical class 0.000 claims description 2
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125000004435 hydrogen atoms Chemical class [H]* 0.000 claims 2
DSSYKIVIOFKYAU-UHFFFAOYSA-N Camphor Chemical compound C1CC2(C)C(=O)CC1C2(C)C DSSYKIVIOFKYAU-UHFFFAOYSA-N 0.000 claims 1
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241000723346 Cinnamomum camphora Species 0.000 claims 1
229940010383 Mycobacterium tuberculosis Drugs 0.000 claims 1
ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Natural products OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 1
150000001299 aldehydes Chemical class 0.000 claims 1
150000001371 alpha-amino acids Chemical class 0.000 claims 1
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125000002587 enol group Chemical group 0.000 claims 1
150000002576 ketones Chemical class 0.000 claims 1
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239000003242 anti bacterial agent Substances 0.000 description 34
229940064005 Antibiotic throat preparations Drugs 0.000 description 33
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239000000203 mixture Substances 0.000 description 28
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VTYYLEPIZMXCLO-UHFFFAOYSA-L calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 16
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