BE1002134A5 - RECOMBINANT AVIPOX VIRUS. - Google Patents
RECOMBINANT AVIPOX VIRUS. Download PDFInfo
- Publication number
- BE1002134A5 BE1002134A5 BE8800978A BE8800978A BE1002134A5 BE 1002134 A5 BE1002134 A5 BE 1002134A5 BE 8800978 A BE8800978 A BE 8800978A BE 8800978 A BE8800978 A BE 8800978A BE 1002134 A5 BE1002134 A5 BE 1002134A5
- Authority
- BE
- Belgium
- Prior art keywords
- avipox
- avipox virus
- source
- recombinant avipox
- vertebrate
- Prior art date
Links
- 241000700663 Avipoxvirus Species 0.000 title abstract 3
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 2
- 244000052769 pathogen Species 0.000 abstract 2
- 230000001717 pathogenic effect Effects 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
- Virology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La présente invention fournit un procédé pour induire une réponse immunoligique vis-à-vis d'un pathogène chez un vertébré en inoculant le vertébré à l'aide d'un virus avipox recombinant de synthèse modifié par la présence, dans une région non essentielle du génome de l'avipox, l'ADN provenant de n'importe quelle source qui code pour un antigène du pathogène et exprime cet antigène. La présente invention fournit en outre un virus avipox recombinant de synthèse modifié par l'insertion, à l'intérieur de celui-ci, d'ADN provenant de n'importe quelle source, et en particulier provenant d'une source non avipox, dans une région non essentielle du génome de l'avipox.The present invention provides a method for inducing an immunoligic response to a pathogen in a vertebrate by inoculating the vertebrate using a synthetic recombinant avipox virus modified by the presence in a nonessential region of the avipox genome, DNA from any source that codes for and expresses an antigen of the pathogen. The present invention further provides a synthetic recombinant avipox virus modified by the insertion therein of DNA from any source, and in particular from a non-avipox source, into a nonessential region of the avipox genome.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9071187A | 1987-08-28 | 1987-08-28 | |
US11033587A | 1987-10-20 | 1987-10-20 | |
US18605488A | 1988-04-25 | 1988-04-25 | |
US23439088A | 1988-08-23 | 1988-08-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE1002134A5 true BE1002134A5 (en) | 1990-07-24 |
Family
ID=27492413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE8800978A BE1002134A5 (en) | 1987-08-28 | 1988-08-29 | RECOMBINANT AVIPOX VIRUS. |
Country Status (17)
Country | Link |
---|---|
JP (3) | JP3348156B2 (en) |
KR (1) | KR970011149B1 (en) |
AR (1) | AR241939A1 (en) |
AT (1) | AT408549B (en) |
AU (2) | AU2427588A (en) |
BE (1) | BE1002134A5 (en) |
CH (2) | CH679933A5 (en) |
DE (4) | DE10399032I1 (en) |
DK (1) | DK175904B1 (en) |
FR (1) | FR2621487B1 (en) |
GB (1) | GB2217718B (en) |
IL (1) | IL87581A0 (en) |
IT (1) | IT1229484B (en) |
LU (2) | LU90951I2 (en) |
NL (4) | NL195051C (en) |
NZ (1) | NZ225970A (en) |
WO (1) | WO1989003429A1 (en) |
Families Citing this family (116)
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---|---|---|---|---|
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US5631154A (en) * | 1988-06-10 | 1997-05-20 | Therion Biologics, Incorporated | Self assembled, defective, non-self-propagating lentivirus particles |
ES2061996T3 (en) * | 1988-06-24 | 1994-12-16 | British Tech Group | NON-ESSENTIAL REGIONS OF AVIPOXVIRUSES. |
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