AU777328B2 - Method of promoting bone growth with hyaluronic acid and growth factors - Google Patents

Method of promoting bone growth with hyaluronic acid and growth factors Download PDF

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Publication number
AU777328B2
AU777328B2 AU63797/00A AU6379700A AU777328B2 AU 777328 B2 AU777328 B2 AU 777328B2 AU 63797/00 A AU63797/00 A AU 63797/00A AU 6379700 A AU6379700 A AU 6379700A AU 777328 B2 AU777328 B2 AU 777328B2
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AU
Australia
Prior art keywords
bone
bfgf
composition
hyaluronic acid
site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU63797/00A
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English (en)
Other versions
AU6379700A (en
Inventor
Michael Randomsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DePuy Spine LLC
Original Assignee
DePuy Acromed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DePuy Acromed Inc filed Critical DePuy Acromed Inc
Publication of AU6379700A publication Critical patent/AU6379700A/en
Assigned to DEPUY ACROMED, INC. reassignment DEPUY ACROMED, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: ORQUEST, INC.
Application granted granted Critical
Publication of AU777328B2 publication Critical patent/AU777328B2/en
Priority to AU2005200146A priority Critical patent/AU2005200146B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU63797/00A 1999-07-26 2000-07-26 Method of promoting bone growth with hyaluronic acid and growth factors Ceased AU777328B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2005200146A AU2005200146B2 (en) 1999-07-26 2005-01-13 Method of promoting bone growth with hyaluronic acid and growth factors

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/360,543 US6221854B1 (en) 1996-03-05 1999-07-26 Method of promoting bone growth with hyaluronic acid and growth factors
US09/360543 1999-07-26
PCT/US2000/020373 WO2001007056A1 (en) 1999-07-26 2000-07-26 Method of promoting bone growth with hyaluronic acid and growth factors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2005200146A Division AU2005200146B2 (en) 1999-07-26 2005-01-13 Method of promoting bone growth with hyaluronic acid and growth factors

Publications (2)

Publication Number Publication Date
AU6379700A AU6379700A (en) 2001-02-13
AU777328B2 true AU777328B2 (en) 2004-10-14

Family

ID=23418431

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63797/00A Ceased AU777328B2 (en) 1999-07-26 2000-07-26 Method of promoting bone growth with hyaluronic acid and growth factors

Country Status (7)

Country Link
US (3) US6221854B1 (https=)
EP (1) EP1198235A4 (https=)
JP (2) JP2003505422A (https=)
AU (1) AU777328B2 (https=)
CA (1) CA2378328A1 (https=)
NZ (1) NZ516097A (https=)
WO (1) WO2001007056A1 (https=)

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US20110207666A1 (en) * 1996-03-05 2011-08-25 Depuy Spine, Inc. Method of promoting bone growth with hyaluronic acid and growth factors
US20050043234A1 (en) * 1996-10-16 2005-02-24 Deisher Theresa A. Novel FGF homologs
US6907679B2 (en) * 1998-11-12 2005-06-21 Qlt Usa, Inc. Method for lyophilizing an active agent
US6722054B2 (en) 1998-11-12 2004-04-20 Atrix Laboratories, Inc. Process and delivery container for lyophilizing active agent
US6566144B1 (en) * 2000-03-27 2003-05-20 Atrix Laboratories Cover plate for use in lyophilization
WO2002085422A1 (en) * 2001-04-25 2002-10-31 Eidgenössische Technische Hochschule Zürich Drug delivery matrices to enhance wound healing
US7008626B2 (en) 2001-11-05 2006-03-07 Seikagaku Corporation Medical composition for protuberance of epithelium
US7247609B2 (en) * 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
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JP5449638B2 (ja) * 2002-07-31 2014-03-19 デンツプライ インターナショナル インコーポレーテッド 多孔性粒子およびキャリアゲルを含む骨修復パテ
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
ES2493840T3 (es) * 2002-10-07 2014-09-12 Zymogenetics, Inc. Procedimiento de administración de FGF-18
WO2004062588A2 (en) * 2003-01-06 2004-07-29 University Of Utah Water-soluble polymeric bone-targeting drug delivery system
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
FR2866571B1 (fr) * 2004-02-20 2007-09-21 Philippe Zanchetta Utilisation d'un melange de polysaccharides specifiques denomme par l'inventeur ezbone, comprenant de l'acide hyaluronique, de la chondroitine 6 sulfate, du dermatane sulfate et de l'heparine en cicatrisation osseuse.
ES2706848T3 (es) 2004-07-06 2019-04-01 Zymogenetics Inc Composición farmacéutica que comprende FGF18 y antagonista de IL-1 y método de uso
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20060147443A1 (en) * 2004-12-22 2006-07-06 Kuros Biosurgery Ag Synthetic biomaterials having incorporated therein bioactive factors through enzymatically degradable linkages
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
MX2007008319A (es) * 2005-01-06 2007-10-04 Kuros Biosurgery Ag Matrices suplementadas para la reparacion de fracturas oseas.
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US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
AU2006286158A1 (en) * 2005-09-02 2007-03-08 Colbar Lifescience Ltd. Cross-linked polysaccharide and protein matrices and methods for their preparation
JP2009508596A (ja) 2005-09-19 2009-03-05 ヒストジェニックス コーポレイション 細胞支持基材及びその調製方法
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20080255041A1 (en) * 2007-04-11 2008-10-16 Ebi, L.P. Treatment of annulus fibrosis defects
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
WO2009012367A1 (en) * 2007-07-18 2009-01-22 Aesthetic Science Composition and method of use for soft tissue augmentation/drug delivery
CN101855248B (zh) * 2007-11-13 2012-08-22 生物技术通用（以色列）有限公司 用于粘弹性生物聚合物的稀释过滤灭菌方法
WO2009111069A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
EP2686027B1 (en) 2011-03-16 2021-05-05 Kuros Biosurgery AG Pharmaceutical formulation for use in spinal fusion
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
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EP3411647A4 (en) 2016-02-05 2019-09-25 Tolmar Therapeutics, Inc. VENTED COVER PLATE FOR AN ARRANGEMENT OF SPRAY
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Also Published As

Publication number Publication date
US6703377B2 (en) 2004-03-09
JP2003505422A (ja) 2003-02-12
EP1198235A4 (en) 2006-04-05
EP1198235A1 (en) 2002-04-24
AU6379700A (en) 2001-02-13
US7902172B2 (en) 2011-03-08
US6221854B1 (en) 2001-04-24
US20040176295A1 (en) 2004-09-09
WO2001007056A1 (en) 2001-02-01
US20010014664A1 (en) 2001-08-16
CA2378328A1 (en) 2001-02-01
NZ516097A (en) 2004-02-27
JP2009143949A (ja) 2009-07-02
WO2001007056A9 (en) 2002-07-25

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Owner name: DEPUY ACROMED, INC.

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