AU766095B2 - Neuroimmunophilins for selective neuronal radioprotection - Google Patents

Neuroimmunophilins for selective neuronal radioprotection Download PDF

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Publication number
AU766095B2
AU766095B2 AU95081/98A AU9508198A AU766095B2 AU 766095 B2 AU766095 B2 AU 766095B2 AU 95081/98 A AU95081/98 A AU 95081/98A AU 9508198 A AU9508198 A AU 9508198A AU 766095 B2 AU766095 B2 AU 766095B2
Authority
AU
Australia
Prior art keywords
neuroimmunophilin
radiation
ionizing radiation
neurons
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU95081/98A
Other languages
English (en)
Other versions
AU9508198A (en
Inventor
Eskil Elmer
Marcus Keep
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maas Biolab LLC
Original Assignee
Maas Biolab LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maas Biolab LLC filed Critical Maas Biolab LLC
Publication of AU9508198A publication Critical patent/AU9508198A/en
Application granted granted Critical
Publication of AU766095B2 publication Critical patent/AU766095B2/en
Assigned to MAAS BIOLAB, LLC reassignment MAAS BIOLAB, LLC Alteration of Name(s) of Applicant(s) under S113 Assignors: ELMER, ESKIL, KEEP, MARCUS
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU95081/98A 1998-09-23 1998-09-23 Neuroimmunophilins for selective neuronal radioprotection Ceased AU766095B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/020040 WO2000016794A1 (fr) 1998-09-23 1998-09-23 Neuro-immunophillines pour radioprotection neuronale selective

Publications (2)

Publication Number Publication Date
AU9508198A AU9508198A (en) 2000-04-10
AU766095B2 true AU766095B2 (en) 2003-10-09

Family

ID=22267931

Family Applications (1)

Application Number Title Priority Date Filing Date
AU95081/98A Ceased AU766095B2 (en) 1998-09-23 1998-09-23 Neuroimmunophilins for selective neuronal radioprotection

Country Status (10)

Country Link
EP (1) EP1115412A4 (fr)
JP (1) JP2002526453A (fr)
CN (1) CN1322136A (fr)
AP (1) AP2001002113A0 (fr)
AU (1) AU766095B2 (fr)
BR (1) BR9816047A (fr)
CA (1) CA2345378A1 (fr)
HK (1) HK1040617A1 (fr)
IL (1) IL142120A0 (fr)
WO (1) WO2000016794A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE314084T1 (de) 2000-10-31 2006-01-15 Pharma Mar Sa Kahalalid f formulierung
WO2005103255A1 (fr) * 2004-03-25 2005-11-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Recepteur formylpeptide (fpr) utilise en tant que cible pour une therapie anti-gliome malin
US11745029B2 (en) 2018-05-30 2023-09-05 Zap Surgical Systems, Inc. Radiosurgical neuromodulation close to critical structures

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997018828A1 (fr) * 1995-11-20 1997-05-29 Guilford Pharmaceuticals Inc. Inhibiteurs d'activite de cyclophiline rotamase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE520730C2 (sv) * 1995-01-20 2003-08-19 Eskil Elmer Behandling av hjärnischemi och hjärnskador med ett neuroprotektivt läkemedel

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997018828A1 (fr) * 1995-11-20 1997-05-29 Guilford Pharmaceuticals Inc. Inhibiteurs d'activite de cyclophiline rotamase

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
IDE T ET AL. 9 FEB 96, NEUROSCI LETT,V 204(3) P 157-60 *
TATTON ET AL. ANNNEUROL. V 44 S134-S141 *

Also Published As

Publication number Publication date
CN1322136A (zh) 2001-11-14
CA2345378A1 (fr) 2000-03-30
AU9508198A (en) 2000-04-10
IL142120A0 (en) 2002-03-10
AP2001002113A0 (en) 2001-06-30
HK1040617A1 (zh) 2002-06-21
BR9816047A (pt) 2003-01-07
JP2002526453A (ja) 2002-08-20
EP1115412A4 (fr) 2004-12-15
WO2000016794A1 (fr) 2000-03-30
EP1115412A1 (fr) 2001-07-18

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: MAAS BIOLAB, LLC

Free format text: THE FORMER OWNER WAS: MARCUS KEEP, ESKIL ELMER

FGA Letters patent sealed or granted (standard patent)