AU758576C - Chemokines with amino-terminal modifications - Google Patents
Chemokines with amino-terminal modificationsInfo
- Publication number
- AU758576C AU758576C AU11105/99A AU1110599A AU758576C AU 758576 C AU758576 C AU 758576C AU 11105/99 A AU11105/99 A AU 11105/99A AU 1110599 A AU1110599 A AU 1110599A AU 758576 C AU758576 C AU 758576C
- Authority
- AU
- Australia
- Prior art keywords
- amino
- terminal
- chemokine
- composition
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95582697A | 1997-10-22 | 1997-10-22 | |
| US08/955826 | 1997-10-22 | ||
| AUPCT/US1998/004002 | 1998-02-27 | ||
| PCT/US1998/004002 WO1998038212A2 (en) | 1997-02-28 | 1998-02-27 | Chimeric polypeptides containing chemokine domains |
| US09/175713 | 1998-10-20 | ||
| US09/175,713 US6852508B1 (en) | 1997-02-28 | 1998-10-20 | Chemokine with amino-terminal modifications |
| PCT/US1998/022282 WO1999020759A1 (en) | 1997-10-22 | 1998-10-21 | Chemokines with amino-terminal modifications |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003204941A Division AU2003204941A1 (en) | 1997-10-22 | 2003-06-25 | Chemokines with amino-terminal modifications |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU1110599A AU1110599A (en) | 1999-05-10 |
| AU758576B2 AU758576B2 (en) | 2003-03-27 |
| AU758576C true AU758576C (en) | 2004-04-29 |
Family
ID=56289826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU11105/99A Ceased AU758576C (en) | 1997-10-22 | 1998-10-21 | Chemokines with amino-terminal modifications |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1025229A4 (ja) |
| JP (1) | JP2003526315A (ja) |
| AU (1) | AU758576C (ja) |
| MX (1) | MXPA00003885A (ja) |
| WO (1) | WO1999020759A1 (ja) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001505055A (ja) * | 1996-12-02 | 2001-04-17 | ウエイク・フオレスト・ユニバーシテイ | Ｈｉｖ感染の治療としてのｈｉｖコレセプターの不活性化 |
| WO2000046248A1 (en) * | 1999-02-03 | 2000-08-10 | Schering Corporation | Use of agonists or antagonists of mip-3a in therapy |
| US6645491B1 (en) | 1999-02-03 | 2003-11-11 | Schering Corporation | Method for treating inflammatory conditions using an antibody to MIP-3α |
| JP2003516324A (ja) * | 1999-11-24 | 2003-05-13 | シェーリング コーポレイション | 転移を阻害する方法 |
| US7091310B2 (en) * | 2002-09-13 | 2006-08-15 | Chemokine Therapeutics Corporation | Chemokine analogs for the treatment of human disease |
| DE10027383A1 (de) * | 2000-06-02 | 2001-12-20 | Rhein Biotech Proz & Prod Gmbh | Nukleinsäure-Molekül umfassend eine für ein Chemokin, einen Neuropeptid-Präkursor oder mindestens ein Neuropeptid kodierende Nukleinsäuresequenz |
| IL153789A0 (en) * | 2000-07-12 | 2003-07-31 | Gryphon Therapeutics Inc | Chemokine receptor modulators, production and use |
| WO2002010138A2 (en) * | 2000-08-01 | 2002-02-07 | Schering Corporation | Uses of mammalian genes and related reagents |
| US20020114806A1 (en) * | 2000-09-13 | 2002-08-22 | Annie Pardo-Semo | Uses of mammalian genes and related reagents |
| AU2002235168A1 (en) * | 2000-11-05 | 2002-05-15 | University Of Florida | Targeting pluripotent stem cells to tissues |
| AU2002330053A1 (en) * | 2001-09-20 | 2003-04-01 | Schering Corporation | Chemokines as adjuvants of immune response |
| US20050271639A1 (en) * | 2002-08-22 | 2005-12-08 | Penn Marc S | Genetically engineered cells for therapeutic applications |
| US20140170116A9 (en) | 2002-08-22 | 2014-06-19 | Marc S. Penn | Method of treating ischemic disorders |
| WO2004094465A2 (en) * | 2003-04-23 | 2004-11-04 | The Board Of Trustees Of The University Of Illinois Office Of Technology Management University Of Illinois At Urbana-Champaign | Synthetic molecules that mimic chemokines |
| DK2185719T3 (en) | 2007-08-02 | 2014-02-17 | Novimmune Sa | ANTI-RANTES ANTIBODIES AND PROCEDURES FOR USE THEREOF |
| CA2709398C (en) | 2007-12-14 | 2017-11-07 | The Cleveland Clinic Foundation | Use of stromal cell-derived factor 1 for promoting wound healing |
| EP2473196B1 (en) | 2009-08-28 | 2017-05-31 | The Cleveland Clinic Foundation | Sdf-1 delivery for treating ischemic tissue |
| SG11202103497WA (en) * | 2018-10-22 | 2021-05-28 | Univ Pittsburgh Commonwealth Sys Higher Education | Cleavable activators of cxcr3 and methods of use |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5656456A (en) * | 1992-07-13 | 1997-08-12 | Bionebraska, Inc. | Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof |
| JP3367581B2 (ja) * | 1993-10-14 | 2003-01-14 | 小野薬品工業株式会社 | 新規なポリペプチド、その製造方法、そのポリペプチドをコードするｄｎａ、そのｄｎａからなるベクター、そのベクターで形質転換された宿主細胞 |
| EP0796330A1 (en) * | 1994-12-08 | 1997-09-24 | Glaxo Group Limited | Rantes peptide and fragments and compositions comprising it for treatment of inflammation |
| WO1997037005A1 (en) * | 1996-04-02 | 1997-10-09 | Progenics Pharmaceuticals, Inc. | Method for preventing hiv-1 infection of cd4+ cells |
| FR2751658B1 (fr) * | 1996-07-26 | 1998-10-02 | Pasteur Institut | Utilisation d'une chemokine (sdf-1) ligand pour le recepteur de lestr/fusin/cxcr4 pour prevenir ou traiter l'infection par des virus de type vih |
-
1998
- 1998-02-27 MX MXPA00003885A patent/MXPA00003885A/es unknown
- 1998-10-21 AU AU11105/99A patent/AU758576C/en not_active Ceased
- 1998-10-21 JP JP2000517080A patent/JP2003526315A/ja not_active Withdrawn
- 1998-10-21 EP EP98953836A patent/EP1025229A4/en not_active Withdrawn
- 1998-10-21 WO PCT/US1998/022282 patent/WO1999020759A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1025229A1 (en) | 2000-08-09 |
| WO1999020759A1 (en) | 1999-04-29 |
| MXPA00003885A (es) | 2004-04-23 |
| JP2003526315A (ja) | 2003-09-09 |
| AU758576B2 (en) | 2003-03-27 |
| EP1025229A4 (en) | 2003-06-18 |
| AU1110599A (en) | 1999-05-10 |
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