AU758252B2 - Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts - Google Patents

Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts Download PDF

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Publication number
AU758252B2
AU758252B2 AU88239/98A AU8823998A AU758252B2 AU 758252 B2 AU758252 B2 AU 758252B2 AU 88239/98 A AU88239/98 A AU 88239/98A AU 8823998 A AU8823998 A AU 8823998A AU 758252 B2 AU758252 B2 AU 758252B2
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AU
Australia
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subject
polypeptide
advanced glycation
soluble receptor
srage
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU88239/98A
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English (en)
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AU8823998A (en
Inventor
Ann Marie Schmidt
David Stern
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
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Columbia University in the City of New York
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Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Publication of AU8823998A publication Critical patent/AU8823998A/en
Application granted granted Critical
Publication of AU758252B2 publication Critical patent/AU758252B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Producing Shaped Articles From Materials (AREA)
  • Seasonings (AREA)
  • Special Spraying Apparatus (AREA)
AU88239/98A 1997-08-05 1998-08-05 Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts Ceased AU758252B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/905,709 US7101838B2 (en) 1997-08-05 1997-08-05 Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts
US08/905709 1997-08-05
PCT/US1998/016303 WO1999007402A1 (en) 1997-08-05 1998-08-05 METHOD TO PREVENT ACCELERATED ATHEROSCLEROSIS USING (sRAGE) SOLUBLE RECEPTOR FOR ADVANCED GLYCATION ENDPRODUCTS

Publications (2)

Publication Number Publication Date
AU8823998A AU8823998A (en) 1999-03-01
AU758252B2 true AU758252B2 (en) 2003-03-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU88239/98A Ceased AU758252B2 (en) 1997-08-05 1998-08-05 Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts

Country Status (11)

Country Link
US (2) US7101838B2 (https=)
EP (1) EP1011706B1 (https=)
JP (2) JP4426090B2 (https=)
AT (1) ATE253929T1 (https=)
AU (1) AU758252B2 (https=)
CA (1) CA2299467A1 (https=)
DE (1) DE69819751T8 (https=)
DK (1) DK1011706T3 (https=)
ES (1) ES2210800T3 (https=)
PT (1) PT1011706E (https=)
WO (1) WO1999007402A1 (https=)

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US6613801B2 (en) 2000-05-30 2003-09-02 Transtech Pharma, Inc. Method for the synthesis of compounds of formula I and their uses thereof
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US7087632B2 (en) 2001-03-05 2006-08-08 Transtech Pharma, Inc. Benzimidazole derivatives as therapeutic agents
US7919670B1 (en) 2000-08-14 2011-04-05 The Trustees Of Columbia University In The City Of New York Transgenic mice over-expressing receptor for advanced glycation endproduct (RAGE) in brain and uses thereof
AU2002213192A1 (en) * 2000-10-13 2002-04-22 The Trustees Of Columbia University In The City Of New York A method for inhibiting new tissue growth in blood vessels in a patient subjected to blood vessel injury
CN1494425B (zh) 2001-03-05 2011-12-07 特兰斯泰克制药公司 用作治疗剂的羧酰胺衍生物
JP3837494B2 (ja) 2001-03-19 2006-10-25 国立大学法人金沢大学 可溶型ｒａｇｅタンパク質
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JP5188804B2 (ja) * 2004-08-03 2013-04-24 トランステック ファーマ，インコーポレイティド Ｒａｇｅ融合タンパク質及びその使用方法
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AU2007248784B2 (en) 2006-05-05 2013-11-21 Vtv Therapeutics Llc RAGE fusion proteins, formulations, and methods of use thereof
WO2008100470A2 (en) * 2007-02-15 2008-08-21 Transtech Pharma, Inc. Rage - immunoglobulin fusion proteins
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CL2008002054A1 (es) 2007-07-17 2009-05-29 Hoffmann La Roche Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico.
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US9649376B2 (en) 2010-09-27 2017-05-16 Siwa Corporation Selective removal of age-modified cells for treatment of atherosclerosis
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Also Published As

Publication number Publication date
US20070099829A1 (en) 2007-05-03
AU8823998A (en) 1999-03-01
EP1011706A4 (en) 2001-10-17
JP2001513511A (ja) 2001-09-04
PT1011706E (pt) 2004-04-30
EP1011706A1 (en) 2000-06-28
DE69819751D1 (de) 2003-12-18
DK1011706T3 (da) 2004-03-22
HK1030742A1 (en) 2001-05-18
US20010039256A1 (en) 2001-11-08
WO1999007402A1 (en) 1999-02-18
ATE253929T1 (de) 2003-11-15
US7101838B2 (en) 2006-09-05
JP4426090B2 (ja) 2010-03-03
DE69819751T2 (de) 2004-09-30
DE69819751T8 (de) 2005-01-05
JP2010065040A (ja) 2010-03-25
US7494972B2 (en) 2009-02-24
CA2299467A1 (en) 1999-02-18
JP4976475B2 (ja) 2012-07-18
EP1011706B1 (en) 2003-11-12
ES2210800T3 (es) 2004-07-01

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