DE69819751T8 - VERWENDUNG VON LÖSLICHEM REZEPTOR FÜR FORTGESCHRITTENE GLYKOSILIERUNGS-ENDPRODUKTE (sRAGE) ZUR UNTERDRÜCKUNG DER BESCHLEUNIGTEN ATHERIOSKLEROSE - Google Patents

VERWENDUNG VON LÖSLICHEM REZEPTOR FÜR FORTGESCHRITTENE GLYKOSILIERUNGS-ENDPRODUKTE (sRAGE) ZUR UNTERDRÜCKUNG DER BESCHLEUNIGTEN ATHERIOSKLEROSE Download PDF

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Publication number
DE69819751T8
DE69819751T8 DE69819751T DE69819751T DE69819751T8 DE 69819751 T8 DE69819751 T8 DE 69819751T8 DE 69819751 T DE69819751 T DE 69819751T DE 69819751 T DE69819751 T DE 69819751T DE 69819751 T8 DE69819751 T8 DE 69819751T8
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Prior art keywords
soluble receptor
subject
advanced
glycosilation
srage
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DE69819751T
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German (de)
English (en)
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DE69819751D1 (de
DE69819751T2 (de
Inventor
David Stern
Marie Ann SCHMIDT
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Columbia University in the City of New York
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Columbia University in the City of New York
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Publication of DE69819751T2 publication Critical patent/DE69819751T2/de
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Producing Shaped Articles From Materials (AREA)
  • Seasonings (AREA)
  • Special Spraying Apparatus (AREA)
DE69819751T 1997-08-05 1998-08-05 VERWENDUNG VON LÖSLICHEM REZEPTOR FÜR FORTGESCHRITTENE GLYKOSILIERUNGS-ENDPRODUKTE (sRAGE) ZUR UNTERDRÜCKUNG DER BESCHLEUNIGTEN ATHERIOSKLEROSE Active DE69819751T8 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/905,709 US7101838B2 (en) 1997-08-05 1997-08-05 Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts
US905709 1997-08-05
PCT/US1998/016303 WO1999007402A1 (en) 1997-08-05 1998-08-05 METHOD TO PREVENT ACCELERATED ATHEROSCLEROSIS USING (sRAGE) SOLUBLE RECEPTOR FOR ADVANCED GLYCATION ENDPRODUCTS

Publications (3)

Publication Number Publication Date
DE69819751D1 DE69819751D1 (de) 2003-12-18
DE69819751T2 DE69819751T2 (de) 2004-09-30
DE69819751T8 true DE69819751T8 (de) 2005-01-05

Family

ID=25421326

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69819751T Active DE69819751T8 (de) 1997-08-05 1998-08-05 VERWENDUNG VON LÖSLICHEM REZEPTOR FÜR FORTGESCHRITTENE GLYKOSILIERUNGS-ENDPRODUKTE (sRAGE) ZUR UNTERDRÜCKUNG DER BESCHLEUNIGTEN ATHERIOSKLEROSE

Country Status (11)

Country Link
US (2) US7101838B2 (https=)
EP (1) EP1011706B1 (https=)
JP (2) JP4426090B2 (https=)
AT (1) ATE253929T1 (https=)
AU (1) AU758252B2 (https=)
CA (1) CA2299467A1 (https=)
DE (1) DE69819751T8 (https=)
DK (1) DK1011706T3 (https=)
ES (1) ES2210800T3 (https=)
PT (1) PT1011706E (https=)
WO (1) WO1999007402A1 (https=)

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US7919670B1 (en) 2000-08-14 2011-04-05 The Trustees Of Columbia University In The City Of New York Transgenic mice over-expressing receptor for advanced glycation endproduct (RAGE) in brain and uses thereof
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Also Published As

Publication number Publication date
US20070099829A1 (en) 2007-05-03
AU8823998A (en) 1999-03-01
EP1011706A4 (en) 2001-10-17
JP2001513511A (ja) 2001-09-04
PT1011706E (pt) 2004-04-30
EP1011706A1 (en) 2000-06-28
DE69819751D1 (de) 2003-12-18
DK1011706T3 (da) 2004-03-22
HK1030742A1 (en) 2001-05-18
US20010039256A1 (en) 2001-11-08
WO1999007402A1 (en) 1999-02-18
ATE253929T1 (de) 2003-11-15
US7101838B2 (en) 2006-09-05
JP4426090B2 (ja) 2010-03-03
DE69819751T2 (de) 2004-09-30
JP2010065040A (ja) 2010-03-25
US7494972B2 (en) 2009-02-24
CA2299467A1 (en) 1999-02-18
AU758252B2 (en) 2003-03-20
JP4976475B2 (ja) 2012-07-18
EP1011706B1 (en) 2003-11-12
ES2210800T3 (es) 2004-07-01

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