AU744484B2 - Method for increasing secretion of proteins in eukaryotic host cells - Google Patents

Method for increasing secretion of proteins in eukaryotic host cells Download PDF

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Publication number
AU744484B2
AU744484B2 AU82873/98A AU8287398A AU744484B2 AU 744484 B2 AU744484 B2 AU 744484B2 AU 82873/98 A AU82873/98 A AU 82873/98A AU 8287398 A AU8287398 A AU 8287398A AU 744484 B2 AU744484 B2 AU 744484B2
Authority
AU
Australia
Prior art keywords
host cell
eukaryotic host
cells
cell
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU82873/98A
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English (en)
Other versions
AU8287398A (en
Inventor
Frank Becker
David I. Meyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of AU8287398A publication Critical patent/AU8287398A/en
Application granted granted Critical
Publication of AU744484B2 publication Critical patent/AU744484B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU82873/98A 1997-07-03 1998-07-02 Method for increasing secretion of proteins in eukaryotic host cells Ceased AU744484B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5172197P 1997-07-03 1997-07-03
US60/051721 1997-07-03
PCT/US1998/013870 WO1999001565A1 (en) 1997-07-03 1998-07-02 Method for increasing secretion of proteins in eukaryotic host cells

Publications (2)

Publication Number Publication Date
AU8287398A AU8287398A (en) 1999-01-25
AU744484B2 true AU744484B2 (en) 2002-02-28

Family

ID=21972974

Family Applications (1)

Application Number Title Priority Date Filing Date
AU82873/98A Ceased AU744484B2 (en) 1997-07-03 1998-07-02 Method for increasing secretion of proteins in eukaryotic host cells

Country Status (5)

Country Link
EP (1) EP0991774A4 (ja)
JP (1) JP2002507894A (ja)
AU (1) AU744484B2 (ja)
CA (1) CA2295310A1 (ja)
WO (1) WO1999001565A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001236027A1 (en) * 2000-03-01 2001-09-12 Nippi, Incorporated Substrate for detecting herpes virus protease and process for producing the same
KR20090031359A (ko) 2006-05-16 2009-03-25 교와 핫꼬 기린 가부시키가이샤 단백질의 고분비 생산 방법
KR101791770B1 (ko) 2013-03-26 2017-10-31 가부시키가이샤 닛피 단백질의 제조 방법

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KALIES ET AL (1994) J CELL BIOLOGY V126 PP925-934 *
SAVITZ ET AL (1993) J CELL BIOLOGY V120 PP853-863 *

Also Published As

Publication number Publication date
EP0991774A1 (en) 2000-04-12
JP2002507894A (ja) 2002-03-12
WO1999001565A1 (en) 1999-01-14
AU8287398A (en) 1999-01-25
WO1999001565A9 (en) 1999-04-22
EP0991774A4 (en) 2005-04-06
CA2295310A1 (en) 1999-01-14

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FGA Letters patent sealed or granted (standard patent)