CA2295310A1 - Method for increasing secretion of proteins in eukaryotic host cells - Google Patents

Method for increasing secretion of proteins in eukaryotic host cells Download PDF

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Publication number
CA2295310A1
CA2295310A1 CA002295310A CA2295310A CA2295310A1 CA 2295310 A1 CA2295310 A1 CA 2295310A1 CA 002295310 A CA002295310 A CA 002295310A CA 2295310 A CA2295310 A CA 2295310A CA 2295310 A1 CA2295310 A1 CA 2295310A1
Authority
CA
Canada
Prior art keywords
host cell
cells
eukaryotic host
cell
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002295310A
Other languages
English (en)
French (fr)
Inventor
David I. Meyer
Frank Becker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2295310A1 publication Critical patent/CA2295310A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002295310A 1997-07-03 1998-07-02 Method for increasing secretion of proteins in eukaryotic host cells Abandoned CA2295310A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5172197P 1997-07-03 1997-07-03
US60/051,721 1997-07-03
PCT/US1998/013870 WO1999001565A1 (en) 1997-07-03 1998-07-02 Method for increasing secretion of proteins in eukaryotic host cells

Publications (1)

Publication Number Publication Date
CA2295310A1 true CA2295310A1 (en) 1999-01-14

Family

ID=21972974

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002295310A Abandoned CA2295310A1 (en) 1997-07-03 1998-07-02 Method for increasing secretion of proteins in eukaryotic host cells

Country Status (5)

Country Link
EP (1) EP0991774A4 (ja)
JP (1) JP2002507894A (ja)
AU (1) AU744484B2 (ja)
CA (1) CA2295310A1 (ja)
WO (1) WO1999001565A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001064947A1 (fr) * 2000-03-01 2001-09-07 Nippi, Incorporated Substrat utile pour detecter la protease du virus de l'herpes et procede de production de ce dernier
WO2007132949A1 (ja) 2006-05-16 2007-11-22 National Institute Of Advanced Industrial Science And Technology タンパク質の高分泌生産方法
AU2014245132B2 (en) * 2013-03-26 2020-07-16 Nippi, Incorporated Method for producing protein

Also Published As

Publication number Publication date
EP0991774A4 (en) 2005-04-06
WO1999001565A1 (en) 1999-01-14
AU8287398A (en) 1999-01-25
WO1999001565A9 (en) 1999-04-22
EP0991774A1 (en) 2000-04-12
AU744484B2 (en) 2002-02-28
JP2002507894A (ja) 2002-03-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued