AU733964B2 - Novel flt-3 receptor agonists - Google Patents

Novel flt-3 receptor agonists Download PDF

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Publication number
AU733964B2
AU733964B2 AU49853/97A AU4985397A AU733964B2 AU 733964 B2 AU733964 B2 AU 733964B2 AU 49853/97 A AU49853/97 A AU 49853/97A AU 4985397 A AU4985397 A AU 4985397A AU 733964 B2 AU733964 B2 AU 733964B2
Authority
AU
Australia
Prior art keywords
seq
cells
leu
ser
gin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU49853/97A
Other languages
English (en)
Other versions
AU4985397A (en
Inventor
Yiqing Feng
John P. Mckearn
Charles A. Mcwherter
John C. Minnerly
Nancy I. Minster
Nicholas R Staten
Philip R. Streeter
Susan L. Woulfe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of AU4985397A publication Critical patent/AU4985397A/en
Application granted granted Critical
Publication of AU733964B2 publication Critical patent/AU733964B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU49853/97A 1996-10-25 1997-10-23 Novel flt-3 receptor agonists Ceased AU733964B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3009496P 1996-10-25 1996-10-25
US60/030094 1996-10-25
PCT/US1997/018700 WO1998018923A1 (en) 1996-10-25 1997-10-23 NOVEL flt-3 RECEPTOR AGONISTS

Publications (2)

Publication Number Publication Date
AU4985397A AU4985397A (en) 1998-05-22
AU733964B2 true AU733964B2 (en) 2001-05-31

Family

ID=21852464

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49853/97A Ceased AU733964B2 (en) 1996-10-25 1997-10-23 Novel flt-3 receptor agonists

Country Status (7)

Country Link
US (2) US6660257B1 (enExample)
EP (1) EP0950099A1 (enExample)
JP (1) JP2001503265A (enExample)
AU (1) AU733964B2 (enExample)
BR (1) BR9714355A (enExample)
CA (1) CA2268027A1 (enExample)
WO (1) WO1998018923A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5581476A (en) 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US6291661B1 (en) 1998-07-02 2001-09-18 Immunex Corporation flt3-L mutants and method of use
JP2003523398A (ja) * 2000-02-24 2003-08-05 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ 樹状細胞のインビボ活性化によるアジュバント治療
WO2002100317A2 (en) 2001-05-25 2002-12-19 The Trustees Of The University Of Pennsylvania Targeted particles and methods of using the same
EP1425304B9 (en) 2001-07-11 2010-09-08 Maxygen, Inc. G-csf conjugates
EP1668114B1 (en) * 2003-08-18 2009-11-04 The Regents of the University of California Polypeptide display libraries and methods of making and using thereof
US7506180B2 (en) * 2005-03-10 2009-03-17 Hewlett-Packard Development Company, L.P. System and method for determining the power drawn from a switching power supply by counting the number of times a switching power supply switch is enabled
US7756681B2 (en) 2005-03-10 2010-07-13 Hewlett-Packard Development Company, L.P. Power supply circuit
KR20080027291A (ko) 2005-06-01 2008-03-26 맥시겐 홀딩스 엘티디 피이지화된 지-씨에스에프 폴리펩타이드 및 그 제조방법
AU2006284651C1 (en) 2005-08-31 2013-09-12 The Regents Of The University Of California Cellular libraries of peptide sequences (CLiPS) and methods of using the same
US8293685B2 (en) 2007-07-26 2012-10-23 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
US8921516B2 (en) * 2010-12-08 2014-12-30 Corning Incorporated Synthetic, defined fibronectin mimetic peptides and surfaces modified with the same
US10611837B2 (en) 2014-04-10 2020-04-07 Seattle Children's Hospital Transgene genetic tags and methods of use
AU2016306209B2 (en) 2015-08-07 2023-07-06 Seattle Children's Hospital (dba Seattle Children's Research Institute) Bispecific CAR T-cells for solid tumor targeting
CA3048648A1 (en) 2017-01-10 2018-07-19 The General Hospital Corporation T cells expressing a chimeric antigen receptor
JP7566628B2 (ja) * 2018-01-10 2024-10-15 ザ ジェネラル ホスピタル コーポレイション キメラ抗原受容体を発現する免疫細胞
SG11202104352XA (en) * 2018-12-18 2021-05-28 Boehringer Ingelheim Io Canada Inc Flt3 agonist antibodies and uses thereof
WO2020198659A1 (en) * 2019-03-28 2020-10-01 Orionis Biosciences, Inc. Fms-like tyrosine kinase 3 ligand (flt3l)-based chimeric proteins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7384496A (en) * 1995-10-05 1997-04-28 G.D. Searle & Co. Multi-functional hematopoietic receptor agonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2150495T5 (es) 1993-05-19 2007-02-16 Schering Corporation Ligandos de flt3 purificados de mamifero y agonistas y antagonistas de los mismos.
US5554512A (en) 1993-05-24 1996-09-10 Immunex Corporation Ligands for flt3 receptors
CZ307995A3 (en) 1993-05-24 1996-10-16 Immunex Corp Ligands for flt3 receptors
ATE273383T1 (de) 1994-03-07 2004-08-15 Immunex Corp Ausrüstung für die extrakorporale zellkultur und zelltransplantation
US5635599A (en) 1994-04-08 1997-06-03 The United States Of America As Represented By The Department Of Health And Human Services Fusion proteins comprising circularly permuted ligands

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7384496A (en) * 1995-10-05 1997-04-28 G.D. Searle & Co. Multi-functional hematopoietic receptor agonists

Also Published As

Publication number Publication date
US20040127410A1 (en) 2004-07-01
JP2001503265A (ja) 2001-03-13
BR9714355A (pt) 2000-04-11
WO1998018923A1 (en) 1998-05-07
EP0950099A1 (en) 1999-10-20
AU4985397A (en) 1998-05-22
US6660257B1 (en) 2003-12-09
CA2268027A1 (en) 1998-05-07

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