AU733647B2 - Non-nucleotide linking reagents - Google Patents

Non-nucleotide linking reagents Download PDF

Info

Publication number
AU733647B2
AU733647B2 AU31465/97A AU3146597A AU733647B2 AU 733647 B2 AU733647 B2 AU 733647B2 AU 31465/97 A AU31465/97 A AU 31465/97A AU 3146597 A AU3146597 A AU 3146597A AU 733647 B2 AU733647 B2 AU 733647B2
Authority
AU
Australia
Prior art keywords
nucleotide
group
reagent
recited
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU31465/97A
Other languages
English (en)
Other versions
AU3146597A (en
Inventor
Sunil K. Aggarwal
Rajkumar Siva Iyer
Krishan L. Kalra
George Sheng-Hui Su
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogenex Laboratories Inc
Original Assignee
Biogenex Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenex Laboratories Inc filed Critical Biogenex Laboratories Inc
Publication of AU3146597A publication Critical patent/AU3146597A/en
Application granted granted Critical
Publication of AU733647B2 publication Critical patent/AU733647B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2416—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of cycloaliphatic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
AU31465/97A 1996-05-15 1997-05-15 Non-nucleotide linking reagents Ceased AU733647B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64782096A 1996-05-15 1996-05-15
US08/647820 1996-05-15
PCT/US1997/009094 WO1997043451A1 (en) 1996-05-15 1997-05-15 Non-nucleotide linking reagents

Publications (2)

Publication Number Publication Date
AU3146597A AU3146597A (en) 1997-12-05
AU733647B2 true AU733647B2 (en) 2001-05-17

Family

ID=24598396

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31465/97A Ceased AU733647B2 (en) 1996-05-15 1997-05-15 Non-nucleotide linking reagents

Country Status (8)

Country Link
US (1) US6130323A (enExample)
EP (1) EP0954606B1 (enExample)
JP (1) JP2001509784A (enExample)
AT (1) ATE252158T1 (enExample)
AU (1) AU733647B2 (enExample)
CA (1) CA2253969A1 (enExample)
DE (1) DE69725611T2 (enExample)
WO (1) WO1997043451A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1052510B2 (en) * 1998-11-06 2018-08-01 LSI Medience Corporation Novel complexes containing crosslinked avidin, process for preparing and analytical method using the same
DE60121342T2 (de) 2000-08-11 2007-06-28 Idaho Technology, Inc., Salt Lake City Einfach markierte oligonukleotidsonden
US7560231B2 (en) * 2002-12-20 2009-07-14 Roche Molecular Systems, Inc. Mannitol and glucitol derivatives
WO2004089295A2 (en) * 2003-04-01 2004-10-21 Chromagen, Inc. Homogeneous and heterogeneous assay methods using nucleation centers and novel covalent chemistries for the rapid measurement of phosphorylation and de-phosphorylation
CA2463719A1 (en) 2003-04-05 2004-10-05 F. Hoffmann-La Roche Ag Nucleotide analogs with six membered rings
EP1502958A1 (en) * 2003-08-01 2005-02-02 Roche Diagnostics GmbH New detection format for hot start real time polymerase chain reaction
EP1700922B1 (en) 2005-03-10 2016-08-24 Roche Diagnostics GmbH 3-Substituted 5-Nitroindole derivatives and labeled oligonucleotide probes containing them
EP1801114B8 (de) 2005-11-23 2009-12-02 Roche Diagnostics GmbH Polynukleotid mit Phosphatmimetikum
JP4713514B2 (ja) * 2006-02-20 2011-06-29 エフ．ホフマン−ラ ロシュ アーゲー 改善された標識試薬
EP2156370B1 (en) 2007-05-14 2011-10-12 Historx, Inc. Compartment segregation by pixel characterization using image data clustering
EP2162728B1 (en) 2007-06-15 2016-07-27 Novartis AG Microscope system and method for obtaining standardized sample data
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
WO2009029810A1 (en) 2007-08-31 2009-03-05 Historx, Inc. Automatic exposure time selection for imaging tissue
WO2010033508A1 (en) 2008-09-16 2010-03-25 Historx, Inc. Reproducible quantification of biomarker expression
MX2012003396A (es) 2009-09-16 2012-04-10 Genentech Inc Complejos de proteina conteniendo helice super-enrollada y/o enlazador tether y usos de los mismos.
TW201138821A (en) 2010-03-26 2011-11-16 Roche Glycart Ag Bispecific antibodies
CN103384825B (zh) 2010-12-23 2017-05-24 霍夫曼-拉罗奇有限公司 通过二价结合剂检测经翻译后修饰的多肽
JP5766296B2 (ja) 2010-12-23 2015-08-19 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
CN104105711B (zh) 2012-02-10 2018-11-30 弗·哈夫曼-拉罗切有限公司 单链抗体及其他异多聚体
EP2867253B1 (en) 2012-06-27 2016-09-14 F. Hoffmann-La Roche AG Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof
MX2014014804A (es) 2012-06-27 2015-02-12 Hoffmann La Roche Metodo para la elaboracion de conjugados de la region fc de anticuerpos que comprenden por lo menos una entidad de union que se une especificamente a un objetivo y usos del mismo.
CN107001482B (zh) 2014-12-03 2021-06-15 豪夫迈·罗氏有限公司 多特异性抗体
EP3484908A4 (en) * 2016-07-15 2020-04-08 AM Chemicals Llc NON-NUCLEOSIDIC SOLID CARRIERS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTID SYNTHESIS
CN108219513B (zh) * 2018-03-14 2019-11-08 青岛科技大学 一种羧基荧光素的制备方法

Also Published As

Publication number Publication date
AU3146597A (en) 1997-12-05
US6130323A (en) 2000-10-10
EP0954606A1 (en) 1999-11-10
CA2253969A1 (en) 1997-11-20
DE69725611D1 (de) 2003-11-20
WO1997043451A1 (en) 1997-11-20
DE69725611T2 (de) 2004-07-29
JP2001509784A (ja) 2001-07-24
ATE252158T1 (de) 2003-11-15
EP0954606B1 (en) 2003-10-15
EP0954606A4 (enExample) 1999-12-22

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