AU732079B2 - Novel vitamin D receptor related polypeptides, nucleic acid sequence encoding the same and uses thereof - Google Patents
Novel vitamin D receptor related polypeptides, nucleic acid sequence encoding the same and uses thereof Download PDFInfo
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- AU732079B2 AU732079B2 AU90131/98A AU9013198A AU732079B2 AU 732079 B2 AU732079 B2 AU 732079B2 AU 90131/98 A AU90131/98 A AU 90131/98A AU 9013198 A AU9013198 A AU 9013198A AU 732079 B2 AU732079 B2 AU 732079B2
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- 210000002027 skeletal muscle Anatomy 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000012453 solvate Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 125000003003 spiro group Chemical group 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 239000003270 steroid hormone Substances 0.000 description 1
- 108020001568 subdomains Proteins 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 229940037128 systemic glucocorticoids Drugs 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
- 108010080629 tryptophan-leucine Proteins 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 108010027345 wheylin-1 peptide Proteins 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9703745A SE9703745D0 (sv) | 1997-10-14 | 1997-10-14 | New receptors |
| SE9703745 | 1997-10-14 | ||
| SE9801148A SE9801148D0 (sv) | 1997-10-14 | 1998-03-31 | New receptors |
| SE9801148 | 1998-03-31 | ||
| PCT/SE1998/001548 WO1999019354A1 (fr) | 1997-10-14 | 1998-08-31 | Nouveaux polypeptides apparentes au recepteur de vitamine d, sequence d'acide nucleique codant ces polypeptides et utilisation de ces derniers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU9013198A AU9013198A (en) | 1999-05-03 |
| AU732079B2 true AU732079B2 (en) | 2001-04-12 |
Family
ID=26663102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU90131/98A Ceased AU732079B2 (en) | 1997-10-14 | 1998-08-31 | Novel vitamin D receptor related polypeptides, nucleic acid sequence encoding the same and uses thereof |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1023323A1 (fr) |
| JP (1) | JP2001519441A (fr) |
| KR (1) | KR20010031120A (fr) |
| CN (1) | CN1134452C (fr) |
| AU (1) | AU732079B2 (fr) |
| CA (1) | CA2306453A1 (fr) |
| NZ (1) | NZ504025A (fr) |
| SE (1) | SE9801148D0 (fr) |
| WO (1) | WO1999019354A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003200641B2 (en) * | 1998-01-09 | 2008-04-03 | The Salk Institute For Biological Studies | Novel Steroid-activated Nuclear Receptors and Uses therefor |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002508393A (ja) * | 1997-12-12 | 2002-03-19 | メルク エンド カムパニー インコーポレーテッド | ヒト核内受容体タンパク質ｎＮＲ７およびｎＮＲ７−１をコードするＤＮＡ分子 |
| US6984773B1 (en) | 1998-01-09 | 2006-01-10 | The Salk Institute For Biological Studies | Transgenic mice expressing a human SXR receptor polypeptide |
| US6911537B2 (en) * | 1998-01-09 | 2005-06-28 | The Salk Institute For Biological Studies | Xenobiotic compound modulated expression systems and uses therefor |
| US6756491B2 (en) | 1998-01-09 | 2004-06-29 | The Salk Institute For Biological Studies | Steroid-activated nuclear receptors and uses therefor |
| US7238491B1 (en) | 1998-03-27 | 2007-07-03 | Smithkline Beecham Corporation | Pregnane X receptor method |
| EP1066320A4 (fr) * | 1998-03-27 | 2005-03-16 | Glaxo Group Ltd | Recepteur nucleaire orphelin |
| FR2801311B1 (fr) * | 1999-11-22 | 2005-08-26 | Centre Nat Rech Scient | Polypeptides derives du recepteur nucleaire de la vitamine d, et leurs utilisations notamment dans le cadre du criblage d'analogues de la vitamine d |
| AU2006200258B2 (en) * | 1999-12-09 | 2009-04-09 | The Salk Institute For Biological Studies | Novel steroid-activated nuclear receptors and uses therefor |
| US6514941B1 (en) | 1999-12-10 | 2003-02-04 | Campina Melkunie B.V. | Method of preparing a casein hydrolysate enriched in anti-hypertensive peptides |
| US20040053866A1 (en) * | 2002-08-21 | 2004-03-18 | The Regents Of The University Of California | Tumor suppressor genes and their uses |
| SE0400489D0 (sv) * | 2004-02-27 | 2004-02-27 | Biovitrum Ab | Therapeutic proteins |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996022390A1 (fr) * | 1995-01-17 | 1996-07-25 | The Salk Institute For Biological Studies | Polypeptides, sequence nucleotidique du xor-6, un recepteur analogue a la vitamine d, provenant du dactylethre, et procedes associes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0407462A4 (en) * | 1988-03-30 | 1992-02-05 | Arch Development Corporation | Dna binding proteins including androgen receptor |
| WO1993006215A1 (fr) * | 1991-09-17 | 1993-04-01 | The Salk Institute For Biological Studies | Recepteurs de la superfamille des recepteurs d'hormones thyroidiennes/steroides |
| US5756448A (en) * | 1992-02-26 | 1998-05-26 | The General Hospital Corporation | Constitute activator of retinoid (CAR) receptor polypeptides |
| WO1996036230A1 (fr) * | 1995-05-16 | 1996-11-21 | The Salk Institute For Biological Studies | Modulateurs pour de nouveaux membres de la superfamille des recepteurs steroide/thyroide |
-
1998
- 1998-03-31 SE SE9801148A patent/SE9801148D0/xx unknown
- 1998-08-31 EP EP98941985A patent/EP1023323A1/fr not_active Withdrawn
- 1998-08-31 WO PCT/SE1998/001548 patent/WO1999019354A1/fr not_active Application Discontinuation
- 1998-08-31 KR KR1020007004011A patent/KR20010031120A/ko not_active Application Discontinuation
- 1998-08-31 CN CNB988112264A patent/CN1134452C/zh not_active Expired - Fee Related
- 1998-08-31 NZ NZ504025A patent/NZ504025A/xx unknown
- 1998-08-31 CA CA002306453A patent/CA2306453A1/fr not_active Abandoned
- 1998-08-31 AU AU90131/98A patent/AU732079B2/en not_active Ceased
- 1998-08-31 JP JP2000515925A patent/JP2001519441A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996022390A1 (fr) * | 1995-01-17 | 1996-07-25 | The Salk Institute For Biological Studies | Polypeptides, sequence nucleotidique du xor-6, un recepteur analogue a la vitamine d, provenant du dactylethre, et procedes associes |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003200641B2 (en) * | 1998-01-09 | 2008-04-03 | The Salk Institute For Biological Studies | Novel Steroid-activated Nuclear Receptors and Uses therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ504025A (en) | 2003-04-29 |
| WO1999019354A9 (fr) | 1999-12-02 |
| CA2306453A1 (fr) | 1999-04-22 |
| AU9013198A (en) | 1999-05-03 |
| JP2001519441A (ja) | 2001-10-23 |
| SE9801148D0 (sv) | 1998-03-31 |
| KR20010031120A (ko) | 2001-04-16 |
| EP1023323A1 (fr) | 2000-08-02 |
| WO1999019354A1 (fr) | 1999-04-22 |
| CN1279689A (zh) | 2001-01-10 |
| CN1134452C (zh) | 2004-01-14 |
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Owner name: PHARMACIA AB Free format text: FORMER NAME: PHARMACIA AND UPJOHN AB |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| PC | Assignment registered |
Owner name: BIOVITRUM AB Free format text: FORMER OWNER WAS: PHARMACIA AB |