AU726892B2 - Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof - Google Patents
Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof Download PDFInfo
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- AU726892B2 AU726892B2 AU25984/97A AU2598497A AU726892B2 AU 726892 B2 AU726892 B2 AU 726892B2 AU 25984/97 A AU25984/97 A AU 25984/97A AU 2598497 A AU2598497 A AU 2598497A AU 726892 B2 AU726892 B2 AU 726892B2
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- 229960005225 mifamurtide Drugs 0.000 description 1
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- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
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- 108091005573 modified proteins Proteins 0.000 description 1
- 102000035118 modified proteins Human genes 0.000 description 1
- 238000000329 molecular dynamics simulation Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 229940035032 monophosphoryl lipid a Drugs 0.000 description 1
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- 239000013642 negative control Substances 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 1
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 1
- JPXMTWWFLBLUCD-UHFFFAOYSA-N nitro blue tetrazolium(2+) Chemical compound COC1=CC(C=2C=C(OC)C(=CC=2)[N+]=2N(N=C(N=2)C=2C=CC=CC=2)C=2C=CC(=CC=2)[N+]([O-])=O)=CC=C1[N+]1=NC(C=2C=CC=CC=2)=NN1C1=CC=C([N+]([O-])=O)C=C1 JPXMTWWFLBLUCD-UHFFFAOYSA-N 0.000 description 1
- 230000009871 nonspecific binding Effects 0.000 description 1
- 238000007899 nucleic acid hybridization Methods 0.000 description 1
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- 238000002515 oligonucleotide synthesis Methods 0.000 description 1
- 101150016099 omcA gene Proteins 0.000 description 1
- 229940126578 oral vaccine Drugs 0.000 description 1
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- 229940092253 ovalbumin Drugs 0.000 description 1
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- 239000008194 pharmaceutical composition Substances 0.000 description 1
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- 150000004633 phorbol derivatives Chemical class 0.000 description 1
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- 230000001766 physiological effect Effects 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000013600 plasmid vector Substances 0.000 description 1
- 108010054442 polyalanine Proteins 0.000 description 1
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- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
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- 229920000053 polysorbate 80 Polymers 0.000 description 1
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- 230000001124 posttranscriptional effect Effects 0.000 description 1
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- 230000008569 process Effects 0.000 description 1
- 230000009465 prokaryotic expression Effects 0.000 description 1
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- 238000000734 protein sequencing Methods 0.000 description 1
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- 239000000612 proton pump inhibitor Substances 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 229940126583 recombinant protein vaccine Drugs 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
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- 230000002829 reductive effect Effects 0.000 description 1
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 description 1
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- 238000007363 ring formation reaction Methods 0.000 description 1
- 229920002477 rna polymer Polymers 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 230000009863 secondary prevention Effects 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
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- 238000000926 separation method Methods 0.000 description 1
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- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 210000002027 skeletal muscle Anatomy 0.000 description 1
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- 238000005063 solubilization Methods 0.000 description 1
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- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 238000011272 standard treatment Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
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- 239000000829 suppository Substances 0.000 description 1
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- 229960004072 thrombin Drugs 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- 229940113082 thymine Drugs 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical class [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 230000001810 trypsinlike Effects 0.000 description 1
- 238000010396 two-hybrid screening Methods 0.000 description 1
- 108010087967 type I signal peptidase Proteins 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 230000009452 underexpressoin Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 210000003934 vacuole Anatomy 0.000 description 1
- 125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 108700026220 vif Genes Proteins 0.000 description 1
- 239000000304 virulence factor Substances 0.000 description 1
- 230000007923 virulence factor Effects 0.000 description 1
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- 238000001262 western blot Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62581196A | 1996-03-29 | 1996-03-29 | |
| US08/625811 | 1996-03-29 | ||
| US75873196A | 1996-04-02 | 1996-04-02 | |
| US08/758731 | 1996-04-02 | ||
| US73690596A | 1996-10-25 | 1996-10-25 | |
| US08/736905 | 1996-10-25 | ||
| US73885996A | 1996-10-28 | 1996-10-28 | |
| US08/738859 | 1996-10-28 | ||
| US76131896A | 1996-12-06 | 1996-12-06 | |
| US08/761318 | 1996-12-06 | ||
| PCT/US1997/005223 WO1997037044A1 (fr) | 1996-03-29 | 1997-03-27 | Acide nucleique et sequence d'acides amines pour lutter contre helicobacter pylori et compositions de vaccins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2598497A AU2598497A (en) | 1997-10-22 |
| AU726892B2 true AU726892B2 (en) | 2000-11-23 |
Family
ID=27542009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU25984/97A Ceased AU726892B2 (en) | 1996-03-29 | 1997-03-27 | Nucleic acid and amino acid sequences relating to helicobacter pylori and vaccine compositions thereof |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0901530A1 (fr) |
| JP (1) | JP2000501621A (fr) |
| CN (1) | CN1220703A (fr) |
| AU (1) | AU726892B2 (fr) |
| BR (1) | BR9708456A (fr) |
| CA (1) | CA2248985A1 (fr) |
| CZ (1) | CZ297698A3 (fr) |
| EE (1) | EE9800334A (fr) |
| HU (1) | HUP0100267A3 (fr) |
| ID (1) | ID18542A (fr) |
| IL (1) | IL125808A0 (fr) |
| IS (1) | IS4831A (fr) |
| NO (1) | NO984517L (fr) |
| NZ (1) | NZ332565A (fr) |
| PL (1) | PL329045A1 (fr) |
| SK (1) | SK130598A3 (fr) |
| TR (1) | TR199801939T2 (fr) |
| WO (1) | WO1997037044A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4368944B2 (ja) * | 1995-04-21 | 2009-11-18 | シーエスエル、リミテッド | 防御用ヘリコバクター抗原 |
| EP1021458A4 (fr) * | 1996-11-14 | 2001-12-12 | Merieux Oravax | Polypeptides helicobacter et molecules de polynucleotides correspondantes |
| SE9702240D0 (sv) * | 1997-06-12 | 1997-06-12 | Astra Ab | Vaccine compositions III |
| NZ541361A (en) | 1998-05-01 | 2008-04-30 | Inst Genomic Research | Neisseria meningitidis antigens and compositions relating to SEQ ID Nos:2916, 2918 and 2920 |
| AU4718999A (en) * | 1998-06-26 | 2000-01-17 | American Cyanamid Company | Novel antigens of (helicobacter pylori) |
| DE19847628C2 (de) * | 1998-10-15 | 2000-10-19 | Chiron Behring Gmbh & Co | Helicobacter pylori-Impfstoff |
| GB9825184D0 (en) * | 1998-11-17 | 1999-01-13 | Cortecs Uk Ltd | Antigen |
| JP2002542821A (ja) | 1999-04-30 | 2002-12-17 | ハイブリジェニックス・ソシエテ・アノニム | ツーハイブリッドシステムのための原核ｄｎａコレクション、ヘリコバクター・ピロリのタンパク質−タンパク質相互作用およびその用途 |
| SE0001988D0 (sv) * | 2000-05-29 | 2000-05-29 | A & Science Invest Ab | Novel polypeptides and use thereof |
| EP1337647A2 (fr) * | 2000-11-15 | 2003-08-27 | Ludwig Deml | Helicobacter cystein rich protein a (hcpa) et ses utilisations |
| US7033790B2 (en) | 2001-04-03 | 2006-04-25 | Curagen Corporation | Proteins and nucleic acids encoding same |
| TW200303919A (en) * | 2001-12-05 | 2003-09-16 | Hiroyuki Ohno | Cytotoxic protein and the use |
| US10828358B2 (en) * | 2015-12-14 | 2020-11-10 | Technische Universität München | Helicobacter pylori vaccines |
| CN106868024B (zh) * | 2017-04-01 | 2020-03-17 | 山东新创生物科技有限公司 | 一种戈氏梭菌特异性pcr检测引物及方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6327896A (en) * | 1995-06-07 | 1996-12-30 | Astra Aktiebolag | Nucleic acid and amino acid sequences relating to helicobacter pylori for diagnostics and therapeutics |
-
1997
- 1997-03-27 ID IDP971050A patent/ID18542A/id unknown
- 1997-03-27 CA CA002248985A patent/CA2248985A1/fr not_active Abandoned
- 1997-03-27 WO PCT/US1997/005223 patent/WO1997037044A1/fr not_active Application Discontinuation
- 1997-03-27 NZ NZ332565A patent/NZ332565A/xx unknown
- 1997-03-27 SK SK1305-98A patent/SK130598A3/sk unknown
- 1997-03-27 CZ CZ982976A patent/CZ297698A3/cs unknown
- 1997-03-27 PL PL97329045A patent/PL329045A1/xx unknown
- 1997-03-27 IL IL12580897A patent/IL125808A0/xx unknown
- 1997-03-27 EP EP97917731A patent/EP0901530A1/fr not_active Withdrawn
- 1997-03-27 HU HU0100267A patent/HUP0100267A3/hu unknown
- 1997-03-27 EE EE9800334A patent/EE9800334A/xx unknown
- 1997-03-27 BR BR9708456A patent/BR9708456A/pt not_active IP Right Cessation
- 1997-03-27 CN CN97195113A patent/CN1220703A/zh active Pending
- 1997-03-27 JP JP9529649A patent/JP2000501621A/ja active Pending
- 1997-03-27 TR TR1998/01939T patent/TR199801939T2/xx unknown
- 1997-03-27 AU AU25984/97A patent/AU726892B2/en not_active Ceased
-
1998
- 1998-08-21 IS IS4831A patent/IS4831A/is unknown
- 1998-09-28 NO NO984517A patent/NO984517L/no unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6327896A (en) * | 1995-06-07 | 1996-12-30 | Astra Aktiebolag | Nucleic acid and amino acid sequences relating to helicobacter pylori for diagnostics and therapeutics |
Also Published As
| Publication number | Publication date |
|---|---|
| SK130598A3 (en) | 1999-06-11 |
| EP0901530A1 (fr) | 1999-03-17 |
| EE9800334A (et) | 1999-04-15 |
| NO984517D0 (no) | 1998-09-28 |
| PL329045A1 (en) | 1999-03-01 |
| CN1220703A (zh) | 1999-06-23 |
| JP2000501621A (ja) | 2000-02-15 |
| WO1997037044A1 (fr) | 1997-10-09 |
| ID18542A (id) | 1998-04-16 |
| HUP0100267A2 (hu) | 2001-06-28 |
| CZ297698A3 (cs) | 1999-02-17 |
| TR199801939T2 (xx) | 1999-02-22 |
| BR9708456A (pt) | 1999-08-03 |
| HUP0100267A3 (en) | 2002-09-30 |
| IS4831A (is) | 1998-08-21 |
| CA2248985A1 (fr) | 1997-10-09 |
| AU2598497A (en) | 1997-10-22 |
| NO984517L (no) | 1998-11-25 |
| IL125808A0 (en) | 1999-04-11 |
| NZ332565A (en) | 2000-03-27 |
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