AU698465B2 - Electrochemiluminescent enzyme biosensors - Google Patents

Electrochemiluminescent enzyme biosensors Download PDF

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Publication number
AU698465B2
AU698465B2 AU63822/96A AU6382296A AU698465B2 AU 698465 B2 AU698465 B2 AU 698465B2 AU 63822/96 A AU63822/96 A AU 63822/96A AU 6382296 A AU6382296 A AU 6382296A AU 698465 B2 AU698465 B2 AU 698465B2
Authority
AU
Australia
Prior art keywords
conjugate
dehydrogenase
enzyme
nad
oxidoreductase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU63822/96A
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English (en)
Other versions
AU6382296A (en
Inventor
Mark T Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioveris Corp
Original Assignee
IGEN International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IGEN International Inc filed Critical IGEN International Inc
Publication of AU6382296A publication Critical patent/AU6382296A/en
Application granted granted Critical
Publication of AU698465B2 publication Critical patent/AU698465B2/en
Assigned to IGEN INTERNATIONAL, INC. reassignment IGEN INTERNATIONAL, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: IGEN, INC.
Assigned to BIOVERIS CORPORATION reassignment BIOVERIS CORPORATION Alteration of Name(s) in Register under S187 Assignors: IGEN INTERNATIONAL, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Luminescent Compositions (AREA)
AU63822/96A 1995-06-06 1996-06-06 Electrochemiluminescent enzyme biosensors Ceased AU698465B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/467,712 US6852502B1 (en) 1995-06-06 1995-06-06 Electrochemiluminescent enzyme biosensors
US08/467712 1995-06-06
PCT/US1996/009869 WO1996039534A1 (en) 1995-06-06 1996-06-06 Electrochemiluminescent enzyme biosensors

Publications (2)

Publication Number Publication Date
AU6382296A AU6382296A (en) 1996-12-24
AU698465B2 true AU698465B2 (en) 1998-10-29

Family

ID=23856828

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63822/96A Ceased AU698465B2 (en) 1995-06-06 1996-06-06 Electrochemiluminescent enzyme biosensors

Country Status (8)

Country Link
US (1) US6852502B1 (https=)
EP (1) EP0837949B1 (https=)
JP (1) JP3618759B2 (https=)
AT (1) ATE254186T1 (https=)
AU (1) AU698465B2 (https=)
CA (1) CA2223017A1 (https=)
DE (1) DE69630688T2 (https=)
WO (1) WO1996039534A1 (https=)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010003647A1 (en) * 1995-06-07 2001-06-14 Ji Sun Coreatant-including electrochemiluminescent compounds, methods, systems and kits utilizing same
JPH11502617A (ja) * 1995-03-10 1999-03-02 メソ スケール テクノロジーズ，エルエルシー 多重アレイの多重特異的な電気化学発光試験
US6140045A (en) * 1995-03-10 2000-10-31 Meso Scale Technologies Multi-array, multi-specific electrochemiluminescence testing
US6673533B1 (en) 1995-03-10 2004-01-06 Meso Scale Technologies, Llc. Multi-array multi-specific electrochemiluminescence testing
US6319670B1 (en) 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
US7766730B2 (en) 2000-11-03 2010-08-03 Cargill, Incorporated Carcass tracking
US7400256B2 (en) 2000-11-03 2008-07-15 Cargill, Incorporated Chill cooler storage and selection system
US6724309B2 (en) 2000-11-03 2004-04-20 Excel Corporation Method and apparatus for tracking carcasses
DE60322708D1 (de) 2002-06-17 2008-09-18 Arkray Inc Glucosesensor unter verwendung von glucosedehydrogenase
JP5590796B2 (ja) * 2005-06-03 2014-09-17 ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システム 電気化学および単一ファラデー電極による電気化学発光
WO2007056338A2 (en) 2005-11-08 2007-05-18 Surmodics, Inc. Ultra-thin photo-polymeric coatings and uses thereof
CN107501407B (zh) 2007-03-30 2022-03-18 Ambrx公司 经修饰fgf-21多肽和其用途
US8008037B2 (en) 2008-03-27 2011-08-30 Roche Diagnostics Operations, Inc. Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline
PT2271938E (pt) 2008-04-11 2014-05-09 Univ Texas Método e aparelho de amplificação de quimiluminescênci electrogerada por nanopartículas
AU2009244904B2 (en) 2008-05-08 2014-04-17 Board Of Regents Of The University Of Texas System Luminescent nanostructured materials for use in electrogenerated chemiluminescence
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9075042B2 (en) 2012-05-15 2015-07-07 Wellstat Diagnostics, Llc Diagnostic systems and cartridges
CN114805532A (zh) 2014-10-24 2022-07-29 百时美施贵宝公司 修饰的fgf-21多肽及其用途
JP6979941B2 (ja) 2015-08-20 2021-12-15 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Ｐｅｇ化分析物特異的結合剤を用いた粒子に基づくイムノアッセイ
BR112018017336A2 (pt) 2016-03-07 2018-12-26 Hoffmann La Roche método in vitro para detectar um anticorpo para p53 (anticorpo anti-p53) em uma amostra e polipeptídeo de fusão
JP7068323B2 (ja) 2017-02-02 2022-05-16 エフ．ホフマン－ラ ロシュ アーゲー 少なくとも２種のペグ化された分析物特異的結合剤を使用する免疫アッセイ
EP3781600A1 (en) 2018-04-18 2021-02-24 F. Hoffmann-La Roche AG Novel anti-thymidine kinase antibodies
JP7577647B2 (ja) 2018-08-31 2024-11-05 エフ． ホフマン－ラ ロシュ アーゲー Ｄｌｂｃｌについての予後指標におけるチミジンキナーゼ（ｔｋ－１）
CN110938667A (zh) * 2018-09-21 2020-03-31 中国科学院天津工业生物技术研究所 一种酶电极、生物传感器及其制备方法和用途
EP4004551A1 (en) 2019-07-22 2022-06-01 F. Hoffmann-La Roche AG Substance p as blood biomarker for the non-invasive diagnosis of endometriosis
WO2021013785A1 (en) 2019-07-22 2021-01-28 F. Hoffmann-La Roche Ag S100a9 as blood biomarker for the non-invasive diagnosis of endometriosis
EP4004555A1 (en) 2019-07-22 2022-06-01 F. Hoffmann-La Roche AG S100a6 as blood biomarker for the non-invasive diagnosis of endometriosis
WO2021013783A1 (en) 2019-07-22 2021-01-28 F. Hoffmann-La Roche Ag S100a12 as blood biomarker for the non-invasive diagnosis of endometriosis
EP4004553A1 (en) 2019-07-22 2022-06-01 F. Hoffmann-La Roche AG S100a8 as blood biomarker for the non-invasive diagnosis of endometriosis
KR20220100883A (ko) 2019-11-15 2022-07-18 에프. 호프만-라 로슈 아게 환자 샘플의 질량분석법 측정을 위한 베타-락탐 항생제의 유도체화
JP7851928B2 (ja) 2020-11-02 2026-04-27 エフ． ホフマン－ラ ロシュ アーゲー ＳＡＲＳ－ＣｏＶ－２ヌクレオカプシド抗体
WO2022207628A1 (en) 2021-03-30 2022-10-06 F. Hoffmann-La Roche Ag Scf as blood biomarker for the non-invasive diagnosis of endometriosis
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CN117337394A (zh) 2021-05-17 2024-01-02 豪夫迈·罗氏有限公司 sFRP4作为血液生物标志物用于子宫腺肌病的非侵入性诊断
WO2023072904A1 (en) 2021-10-26 2023-05-04 F. Hoffmann-La Roche Ag Monoclonal antibodies specific for sars-cov-2 rbd
KR20230060229A (ko) * 2021-10-27 2023-05-04 한국전기연구원 광열 모듈레이션 레이저 스펙클 영상을 이용한 포도당 농도 측정 시스템, 방법, 및 상기 방법을 실행시키기 위한 컴퓨터 판독 가능한 프로그램을 기록한 기록 매체
WO2023131594A1 (en) 2022-01-05 2023-07-13 F. Hoffmann-La Roche Ag Derivatization of compounds in patient samples for therapeutic drug monitoring (tdm)
JP2025520600A (ja) 2022-06-23 2025-07-03 エフ． ホフマン－ラ ロシュ アーゲー 子宮内膜症を診断するためおよび子宮内膜症の病期を分類するための方法
EP4558830A1 (en) 2022-07-22 2025-05-28 F. Hoffmann-La Roche AG Leukotriene a4 hydrolase (lta4h) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
JP2025524027A (ja) 2022-07-22 2025-07-25 エフ． ホフマン－ラ ロシュ アーゲー 多嚢胞性卵巣症候群の診断のための（血液）バイオマーカーとしてのメテオリン様タンパク質（ｍｅｔｒｎｌ）
EP4558826A1 (en) 2022-07-22 2025-05-28 F. Hoffmann-La Roche AG Fibroblast growth factor binding protein 1 (fgfbp1) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
CN120693408A (zh) 2022-12-05 2025-09-23 直接传感有限公司 非乳酸羟基酸的酶促检测
CN121532654A (zh) 2023-07-20 2026-02-13 豪夫迈·罗氏有限公司 针对抗体组合物的筛选方法
CN121752901A (zh) 2023-07-28 2026-03-27 豪夫迈·罗氏有限公司 作为子宫内膜异位症的生物标志物的血清EphA1

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310687A (en) 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US5221605A (en) 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
US5147806A (en) 1988-04-29 1992-09-15 Igen, Inc. Method and apparatus for conducting electrochemiluminescence measurements
US5250415A (en) 1987-04-08 1993-10-05 Merck Patent Gesellschaft Mit Beschrankter Haftung Process for the preparation of glucose dehydrogenase from Bacillus megaterium
US5061455A (en) 1987-04-30 1991-10-29 United Technologies Corporation Apparatus for removing carbon dioxide from air
US5093268A (en) 1988-04-28 1992-03-03 Igen, Inc. Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena
US5340722A (en) 1988-08-24 1994-08-23 Avl Medical Instruments Ag Method for the determination of the concentration of an enzyme substrate and a sensor for carrying out the method
US5068088A (en) 1988-11-03 1991-11-26 Igen, Inc. Method and apparatus for conducting electrochemiluminescent measurements
US5235808A (en) 1990-02-12 1993-08-17 General Electric Company Exhaust nozzle including idle thrust spoiling
US5324835A (en) 1990-03-30 1994-06-28 Biosensor Laboratories Co., Ltd. Pyridazinoquinoxalinones for use as chemiluminescent agents
US5229202A (en) 1990-05-22 1993-07-20 Mitsubishi Kasei Corporation Carbon fiber and carbon fiber-reinforced resin composition using it
US5264092A (en) 1991-10-02 1993-11-23 Moltech Corporation Redox polymer modified electrode for the electrochemical regeneration of coenzyme
JP2541081B2 (ja) 1992-08-28 1996-10-09 日本電気株式会社 バイオセンサ及びバイオセンサの製造・使用方法
US5527710A (en) * 1994-12-02 1996-06-18 Igen, Inc. Rate measurements of biomolecular reactions using electrochemiluminescence
JPH11502617A (ja) * 1995-03-10 1999-03-02 メソ スケール テクノロジーズ，エルエルシー 多重アレイの多重特異的な電気化学発光試験

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CLIN CHEM 37(9) 1991 G.F. BLACKBURNE ET AL PP1534-39 *

Also Published As

Publication number Publication date
ATE254186T1 (de) 2003-11-15
US6852502B1 (en) 2005-02-08
EP0837949A1 (en) 1998-04-29
DE69630688D1 (de) 2003-12-18
AU6382296A (en) 1996-12-24
CA2223017A1 (en) 1996-12-12
EP0837949A4 (en) 2000-05-17
DE69630688T2 (de) 2004-09-23
JP3618759B2 (ja) 2005-02-09
JPH11507536A (ja) 1999-07-06
EP0837949B1 (en) 2003-11-12
WO1996039534A1 (en) 1996-12-12

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Free format text: FORMER OWNER WAS: IGEN INTERNATIONAL, INC.