AU690121B2 - Methods and compositions for detecting and treating mycobacterial infections using an inhA gene - Google Patents

Methods and compositions for detecting and treating mycobacterial infections using an inhA gene Download PDF

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Publication number
AU690121B2
AU690121B2 AU69121/94A AU6912194A AU690121B2 AU 690121 B2 AU690121 B2 AU 690121B2 AU 69121/94 A AU69121/94 A AU 69121/94A AU 6912194 A AU6912194 A AU 6912194A AU 690121 B2 AU690121 B2 AU 690121B2
Authority
AU
Australia
Prior art keywords
inha
inh
polypeptide
mycobacterium
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU69121/94A
Other languages
English (en)
Other versions
AU6912194A (en
Inventor
Asesh Banerjee
Desmond Michael Collins
Geoffrey William De Lisle
William R. Jacobs Jr.
Theresa Mary Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AgResearch Ltd
Albert Einstein College of Medicine
Original Assignee
AgResearch Ltd
Albert Einstein College of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AgResearch Ltd, Albert Einstein College of Medicine filed Critical AgResearch Ltd
Publication of AU6912194A publication Critical patent/AU6912194A/en
Assigned to AgResearch New Zealand Pastoral Agriculture Research Institute, Ltd, ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY reassignment AgResearch New Zealand Pastoral Agriculture Research Institute, Ltd Alteration of Name(s) of Applicant(s) under S113 Assignors: BANERJEE, ASESH, COLLINS, DESMOND MICHAEL, DE LISLE, GEOFFREY WILLIAM, JACOBS, WILLIAM R. JR., WILSON, THERESA MARY
Application granted granted Critical
Publication of AU690121B2 publication Critical patent/AU690121B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AU69121/94A 1993-05-13 1994-05-12 Methods and compositions for detecting and treating mycobacterial infections using an inhA gene Ceased AU690121B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
NZ24762093 1993-05-13
NZ247620 1993-05-13
US6240993A 1993-05-14 1993-05-14
US062409 1993-05-14
PCT/US1994/005344 WO1994026312A1 (en) 1993-05-13 1994-05-12 METHODS AND COMPOSITIONS FOR DETECTING AND TREATING MYCOBACTERIAL INFECTIONS USING AN inhA GENE

Publications (2)

Publication Number Publication Date
AU6912194A AU6912194A (en) 1994-12-12
AU690121B2 true AU690121B2 (en) 1998-04-23

Family

ID=26651188

Family Applications (1)

Application Number Title Priority Date Filing Date
AU69121/94A Ceased AU690121B2 (en) 1993-05-13 1994-05-12 Methods and compositions for detecting and treating mycobacterial infections using an inhA gene

Country Status (5)

Country Link
EP (1) EP0707496A4 (de)
JP (1) JPH09501823A (de)
AU (1) AU690121B2 (de)
CA (1) CA2162868A1 (de)
WO (1) WO1994026312A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2210378A1 (en) * 1994-12-20 1996-06-27 New Zealand Pastoral Agriculture Research Institute Limited Methods and compositions for detecting and treating mycobacterial infections using an ahpcf operon
GB9526178D0 (en) * 1995-12-21 1996-02-21 Taylor John Hermon Novel polynuceotides and polypeptides in pathogenic mycobacteria and their use as diagnostics,vaccines and targets for chemotherapy
WO1999019508A1 (es) * 1997-10-13 1999-04-22 Universidad Autonoma De Nuevo Leon Metodo para determinar la susceptibilidad de microorganismos que contienen acidos micolicos
GB9806093D0 (en) 1998-03-20 1998-05-20 Taylor John Hermon Diagnostics and vaccines for mycobacterial infections of animals and humans
FR2837836B1 (fr) * 2002-03-29 2005-04-22 Centre Nat Rech Scient UTILISATION DE LA PROTEINE Maba (FABG1) DE MYCOBACTERIUM TUBERCULOSIS POUR LA CONCEPTION ET LE CRIBLAGE D'ANTIBIOTIQUES
CN102105596A (zh) 2008-07-02 2011-06-22 尼普洛株式会社 用于检测结核杆菌中的异烟肼敏感性的方法和试验片
BRPI0913658B1 (pt) 2008-07-02 2019-06-25 Nipro Corporation Método, tira de teste e kit para detecção da sensibilidade à isoniazida em mycobacterium tuberculosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2131578T5 (es) * 1992-04-30 2010-03-31 Institut Pasteur Deteccion rapida de resistencia a antibioticos en mycobacterium tuber culosis.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHANG ET AL (1992) NATURE 358 591-3 *

Also Published As

Publication number Publication date
AU6912194A (en) 1994-12-12
CA2162868A1 (en) 1994-11-24
JPH09501823A (ja) 1997-02-25
WO1994026312A1 (en) 1994-11-24
EP0707496A4 (de) 1997-11-12
EP0707496A1 (de) 1996-04-24

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