AU684466B2 - Novel medicinal composition - Google Patents

Novel medicinal composition Download PDF

Info

Publication number
AU684466B2
AU684466B2 AU45835/93A AU4583593A AU684466B2 AU 684466 B2 AU684466 B2 AU 684466B2 AU 45835/93 A AU45835/93 A AU 45835/93A AU 4583593 A AU4583593 A AU 4583593A AU 684466 B2 AU684466 B2 AU 684466B2
Authority
AU
Australia
Prior art keywords
integer
galactopyranosyloxy
compound
formula
galactosylceramide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU45835/93A
Other languages
English (en)
Other versions
AU4583593A (en
Inventor
Koji Kabaya
Yasuhiko Koezuka
Kazuhiro Motoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kirin Brewery Co Ltd
Original Assignee
Kirin Brewery Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery Co Ltd filed Critical Kirin Brewery Co Ltd
Publication of AU4583593A publication Critical patent/AU4583593A/en
Application granted granted Critical
Publication of AU684466B2 publication Critical patent/AU684466B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU45835/93A 1992-07-16 1993-07-15 Novel medicinal composition Ceased AU684466B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP4-212015 1992-07-16
JP21201592 1992-07-16
JP5-85219 1993-03-19
JP8521993 1993-03-19
PCT/JP1993/000984 WO1994002168A1 (fr) 1992-07-16 1993-07-15 Nouvelle composition medicamenteuse

Publications (2)

Publication Number Publication Date
AU4583593A AU4583593A (en) 1994-02-14
AU684466B2 true AU684466B2 (en) 1997-12-18

Family

ID=26426239

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45835/93A Ceased AU684466B2 (en) 1992-07-16 1993-07-15 Novel medicinal composition

Country Status (12)

Country Link
US (3) US5767092A (cg-RX-API-DMAC7.html)
EP (1) EP0650732B1 (cg-RX-API-DMAC7.html)
JP (1) JP3088461B2 (cg-RX-API-DMAC7.html)
KR (1) KR100277621B1 (cg-RX-API-DMAC7.html)
CN (1) CN1084623C (cg-RX-API-DMAC7.html)
AT (1) ATE200224T1 (cg-RX-API-DMAC7.html)
AU (1) AU684466B2 (cg-RX-API-DMAC7.html)
CA (1) CA2140013C (cg-RX-API-DMAC7.html)
DE (1) DE69330096T2 (cg-RX-API-DMAC7.html)
FI (1) FI950166A7 (cg-RX-API-DMAC7.html)
TW (1) TW261533B (cg-RX-API-DMAC7.html)
WO (1) WO1994002168A1 (cg-RX-API-DMAC7.html)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
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US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
JP3717512B2 (ja) * 1992-10-22 2005-11-16 麒麟麦酒株式会社 新規スフィンゴ糖脂質およびその使用
US5780441A (en) * 1993-04-15 1998-07-14 Kirin Beer Kabushiki Kaisha Sphingoglycolipid compounds and therapeutic uses thereof
US6026815A (en) * 1996-10-10 2000-02-22 Gholam A. Peyman Radiopaque liquid as radiation blocking agent
JP2002226377A (ja) * 1996-10-14 2002-08-14 Kirin Brewery Co Ltd 配糖体含有末梢血幹細胞増加剤
TW555562B (en) * 1996-12-27 2003-10-01 Kirin Brewery Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
JP3382957B2 (ja) * 1997-02-05 2003-03-04 麒麟麦酒株式会社 スフィンゴ糖脂質含有凍結乾燥組成物およびその製造法
US6417167B1 (en) 1997-02-05 2002-07-09 Kirin Beer Kabushiki Kaisha Lyophilized compositions containing shingoglycolipid and process for preparing them
JP3495740B2 (ja) * 1997-04-10 2004-02-09 麒麟麦酒株式会社 α−グリコシルセラミドを含有するＮＫＴ細胞活性化剤
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
AU2001268564A1 (en) * 2000-06-22 2002-01-02 The Brigham And Women's Hospital, Inc. Alpha-glycosylceramides for treating bacterial and fungal infections
CN1561389A (zh) * 2001-07-25 2005-01-05 纽约大学 糖基神经酰胺作为用于抗传染病和癌症的疫苗的佐剂的用途
DE60215530T2 (de) * 2001-08-16 2007-05-31 Daiichi Asubio Pharma Co., Ltd. Neues glykolipid, und heilmittel für autoimmunerkrankungen, das dieses als wirkstoff enthält
US8443383B2 (en) * 2002-05-03 2013-05-14 Time Warner Cable Enterprises Llc Use of messages in program signal streams by set-top terminals
KR20050062551A (ko) * 2002-09-20 2005-06-23 기린 비루 가부시키가이샤 α-글리코실세라미드를 유효 성분으로 하는 Ｃ형 간염 바이러스 억제제
AU2003225891A1 (en) * 2003-03-20 2004-11-19 Brigham Young University 6"-amino-6"-deoxygalactosylceramides
US7645873B2 (en) 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
US7309015B2 (en) * 2004-07-14 2007-12-18 Scanbuy, Inc. Mobile device gateway providing access to instant information
KR101243577B1 (ko) 2004-10-07 2013-03-20 아고스 쎄라퓨틱스, 인코포레이티드 성숙 수지상 세포 조성물 및 그의 배양 방법
US8513008B2 (en) 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
US7923013B2 (en) * 2004-12-28 2011-04-12 The Rockefeller University Glycolipids and analogues thereof as antigens for NKT cells
AU2005322027B2 (en) * 2004-12-28 2013-09-12 The Rockefeller University Glycolipids and analogues thereof as antigens for NK Tcells
US9295722B2 (en) 2005-01-28 2016-03-29 The Scripps Research Institute Bacterial glycolipid activation of CD1d-restricted NKT cells
US20090036658A1 (en) * 2005-03-04 2009-02-05 The Regents Of The University Of California Highly efficient synthesis of alpha-O-galactosyl ceramides
CA2613350A1 (en) * 2005-07-01 2007-01-11 Japan As Represented By President Of National Center Of Neurology And Ps Ychiatry Glycolipid derivative and drug containing the same as active component
EP1776963A1 (en) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramides as adjuvants and their uses in pharmaceutical compositions
US20070231344A1 (en) * 2005-10-28 2007-10-04 The Brigham And Women's Hospital, Inc. Conjugate vaccines for non-proteinaceous antigens
PT2056842E (pt) * 2006-04-07 2013-01-24 Univ Chicago Galactosil-ceramidas modificadas para coloração e estimulação de células t assassinas naturais
JP5564672B2 (ja) * 2006-06-30 2014-07-30 ザ スクリプス リサーチ インスティテュート アジュバント及びその使用方法
US8263576B2 (en) * 2006-08-15 2012-09-11 Mayo Foundation For Medical Education And Research Non-natural sphingolipid analogs and uses thereof
US8916164B2 (en) * 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
US8697659B2 (en) * 2007-10-12 2014-04-15 Luigi Panza Analogues of glycolipids useful as immunoadjuvants
EP2058011A1 (en) * 2007-11-07 2009-05-13 Wittycell Nkt cell activating gycolipids covalently bound antigens and/or drug
EP2231145B1 (en) * 2007-12-05 2014-09-17 Wittycell Use of glycosylceramides for enhancing the immune response to antigens
WO2010040710A1 (en) * 2008-10-08 2010-04-15 Wittycell Vaccine composition for use against influenza
PL2939683T3 (pl) 2009-02-16 2017-07-31 Cerenis Therapeutics Holding Sa Mimetyki apolipoproteiny A-I
RS56529B1 (sr) 2010-10-18 2018-02-28 Cerenis Therapeutics Holding Sa Jedinjenja, kompozicije i postupci pogodni za mobilizaciju holesterola
EP2647384B1 (en) 2010-12-02 2018-05-23 Riken IMMUNOTHERAPY USING ALLO-NKT CELLS, CELLS FOR IMMUNOTHERAPY IN WHICH alpha CHAIN OF T-CELL RECEPTOR (TCR) GENE HAS BEEN REARRANGED TO UNIFORM V alpha-J alpha , AND BANKING OF NKT CELLS DERIVED FROM SAID CELLS
WO2013119857A1 (en) 2012-02-07 2013-08-15 The Regents Of The University Of California Glycosphingolipids for use in modulating immune responses
EP2889039B1 (en) 2012-08-22 2017-11-08 Regimmune Corporation Preparation for preventing or treating type i diabetes
US10329315B2 (en) 2012-10-12 2019-06-25 The Brigham And Women's Hospital, Inc. Glycosphingolipids and methods of use thereof
US20150283235A1 (en) 2012-11-05 2015-10-08 Regimmune Corporation Immune-tolerance inducer
US10151745B2 (en) 2012-11-21 2018-12-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for determining the risk of acute graft versus host disease
JP2015205835A (ja) * 2014-04-21 2015-11-19 国立大学法人福井大学 中性子線障害防護剤
IL303285A (en) 2020-12-04 2023-07-01 Regimmune Corp Cd1d-ligand-compound-containing liposome preparation having improved pharmacokinetics

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1666492A (en) * 1991-08-29 1993-04-05 Kyowa Hakko Kirin Co., Ltd. Novel sphingoglycolipid and use thereof

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Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1666492A (en) * 1991-08-29 1993-04-05 Kyowa Hakko Kirin Co., Ltd. Novel sphingoglycolipid and use thereof

Also Published As

Publication number Publication date
CA2140013C (en) 2002-08-27
KR100277621B1 (ko) 2001-02-01
DE69330096D1 (de) 2001-05-10
WO1994002168A1 (fr) 1994-02-03
TW261533B (cg-RX-API-DMAC7.html) 1995-11-01
FI950166A7 (fi) 1995-01-31
DE69330096T2 (de) 2001-10-18
HK1009937A1 (en) 1999-09-17
FI950166A0 (fi) 1995-01-13
JP3088461B2 (ja) 2000-09-18
EP0650732A4 (en) 1998-04-01
AU4583593A (en) 1994-02-14
US6017892A (en) 2000-01-25
ATE200224T1 (de) 2001-04-15
CN1088093A (zh) 1994-06-22
KR950702431A (ko) 1995-07-29
US5767092A (en) 1998-06-16
EP0650732B1 (en) 2001-04-04
EP0650732A1 (en) 1995-05-03
CA2140013A1 (en) 1994-02-03
CN1084623C (zh) 2002-05-15
US6071884A (en) 2000-06-06

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