AU673814B2 - Imidazoquinazoline compounds and their preparation and use - Google Patents

Imidazoquinazoline compounds and their preparation and use

Info

Publication number
AU673814B2
AU673814B2 AU33448/93A AU3344893A AU673814B2 AU 673814 B2 AU673814 B2 AU 673814B2 AU 33448/93 A AU33448/93 A AU 33448/93A AU 3344893 A AU3344893 A AU 3344893A AU 673814 B2 AU673814 B2 AU 673814B2
Authority
AU
Australia
Prior art keywords
compound
cyclopropyl
quinazoline
imidazo
oxadiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU33448/93A
Other languages
English (en)
Other versions
AU3344893A (en
Inventor
Holger Claus Hansen
Marit Kristiansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of AU3344893A publication Critical patent/AU3344893A/en
Application granted granted Critical
Publication of AU673814B2 publication Critical patent/AU673814B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU33448/93A 1991-12-20 1992-12-18 Imidazoquinazoline compounds and their preparation and use Ceased AU673814B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK2042/91 1991-12-20
DK912042A DK204291D0 (da) 1991-12-20 1991-12-20 Heterocykliske forbindelser deres fremstilling og anvendelse
PCT/DK1992/000385 WO1993013103A1 (fr) 1991-12-20 1992-12-18 Composes d'imidazoquinazoline et leur preparation et utilisation

Publications (2)

Publication Number Publication Date
AU3344893A AU3344893A (en) 1993-07-28
AU673814B2 true AU673814B2 (en) 1996-11-28

Family

ID=8109668

Family Applications (1)

Application Number Title Priority Date Filing Date
AU33448/93A Ceased AU673814B2 (en) 1991-12-20 1992-12-18 Imidazoquinazoline compounds and their preparation and use

Country Status (12)

Country Link
EP (1) EP0619820A1 (fr)
JP (1) JPH07502278A (fr)
AU (1) AU673814B2 (fr)
CA (1) CA2125854A1 (fr)
DK (1) DK204291D0 (fr)
FI (1) FI942963A (fr)
IL (1) IL104099A (fr)
NO (1) NO942301L (fr)
NZ (1) NZ246558A (fr)
TW (1) TW211568B (fr)
WO (1) WO1993013103A1 (fr)
ZA (1) ZA929770B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK151890D0 (da) * 1990-06-22 1990-06-22 Ferrosan As Heterocykliske forbindelser deres fremstilling og brug
CN1052724C (zh) * 1996-07-01 2000-05-24 瑞安大药厂股份有限公司 新的光学活性的2,3－二氢咪唑并[1,2－c]喹唑啉衍生物及其制备方法和用途
KR100864364B1 (ko) 2005-12-13 2008-10-17 주식회사 엘지화학 신규한 이미다조퀴나졸린 유도체, 이의 제조방법 및 이를이용한 유기전기소자
JP5486928B2 (ja) 2007-02-26 2014-05-07 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックウレアおよびカルバメートインヒビター
AR069207A1 (es) 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
WO2009075835A1 (fr) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc Inhibiteurs cycliques d'urée de la 11-hydroxystéroïde déhydrogénase 1
CA2729998A1 (fr) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibiteurs de la 11 beta-hydroxysteroide deshydrogenase 1
EP2687525B1 (fr) 2008-07-25 2015-09-23 Boehringer Ingelheim International GmbH Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déshydrogénase 1
WO2010089303A1 (fr) 2009-02-04 2010-08-12 Boehringer Ingelheim International Gmbh Inhibiteurs cycliques de la 11β-hydroxystéroïde déshydrogénase de type 1
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
EP2448928B1 (fr) 2009-07-01 2014-08-13 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déshydrogénase 1
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
WO2011161128A1 (fr) 2010-06-25 2011-12-29 Boehringer Ingelheim International Gmbh Azaspirohexanones comme inhibiteurs de 11-β-hsd1 pour le traitement de troubles métaboliques
WO2012059416A1 (fr) 2010-11-02 2012-05-10 Boehringer Ingelheim International Gmbh Combinaisons pharmaceutiques destinées au traitement de troubles du métabolisme
KR20230088709A (ko) * 2020-10-16 2023-06-20 상하이 드 노보 파마테크 컴퍼니 리미티드 트리헤테로사이클릭 유도체, 이의 약학적 조성물 및 용도

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0226282A2 (fr) * 1985-10-17 1987-06-24 A/S Ferrosan Composés hétérocycliques, leur préparation et leur utilisation
EP0283162A2 (fr) * 1987-03-18 1988-09-21 Novo Nordisk A/S Composés hétérocycliques, leur préparation et utilisation
WO1992000298A1 (fr) * 1990-06-22 1992-01-09 Novo Nordisk A/S Composes heterocycliques, leur preparation et utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK443589D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0226282A2 (fr) * 1985-10-17 1987-06-24 A/S Ferrosan Composés hétérocycliques, leur préparation et leur utilisation
EP0283162A2 (fr) * 1987-03-18 1988-09-21 Novo Nordisk A/S Composés hétérocycliques, leur préparation et utilisation
WO1992000298A1 (fr) * 1990-06-22 1992-01-09 Novo Nordisk A/S Composes heterocycliques, leur preparation et utilisation

Also Published As

Publication number Publication date
IL104099A0 (en) 1993-05-13
EP0619820A1 (fr) 1994-10-19
CA2125854A1 (fr) 1993-07-08
WO1993013103A1 (fr) 1993-07-08
ZA929770B (en) 1994-06-17
DK204291D0 (da) 1991-12-20
JPH07502278A (ja) 1995-03-09
IL104099A (en) 1996-07-23
FI942963A0 (fi) 1994-06-20
NO942301L (no) 1994-08-19
NZ246558A (en) 1995-07-26
NO942301D0 (no) 1994-06-17
FI942963A (fi) 1994-06-20
AU3344893A (en) 1993-07-28
TW211568B (fr) 1993-08-21

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