AU673265B2 - Treatment process with biologically active tropane derivatives - Google Patents

Treatment process with biologically active tropane derivatives Download PDF

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Publication number
AU673265B2
AU673265B2 AU67671/94A AU6767194A AU673265B2 AU 673265 B2 AU673265 B2 AU 673265B2 AU 67671/94 A AU67671/94 A AU 67671/94A AU 6767194 A AU6767194 A AU 6767194A AU 673265 B2 AU673265 B2 AU 673265B2
Authority
AU
Australia
Prior art keywords
group
aryltropane
uptake
hydrogen
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU67671/94A
Other languages
English (en)
Other versions
AU6767194A (en
Inventor
Barbara Bennett
Steven R Childers
Huw M.L. Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wake Forest University
Original Assignee
Wake Forest University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/063,431 external-priority patent/US6008227A/en
Application filed by Wake Forest University filed Critical Wake Forest University
Publication of AU6767194A publication Critical patent/AU6767194A/en
Application granted granted Critical
Publication of AU673265B2 publication Critical patent/AU673265B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU67671/94A 1993-05-18 1994-04-04 Treatment process with biologically active tropane derivatives Ceased AU673265B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/063,431 US6008227A (en) 1992-03-13 1993-05-18 Process for blocking 5-HT and dopamine uptake with biologically active tropane derivatives
US063431 1993-05-18
PCT/US1994/003661 WO1994026274A1 (fr) 1993-05-18 1994-04-04 Therapie faisant appel a des derives biologiquement actifs du tropane

Publications (2)

Publication Number Publication Date
AU6767194A AU6767194A (en) 1994-12-12
AU673265B2 true AU673265B2 (en) 1996-10-31

Family

ID=22049138

Family Applications (1)

Application Number Title Priority Date Filing Date
AU67671/94A Ceased AU673265B2 (en) 1993-05-18 1994-04-04 Treatment process with biologically active tropane derivatives

Country Status (5)

Country Link
EP (1) EP0697871A4 (fr)
JP (1) JP2906085B2 (fr)
AU (1) AU673265B2 (fr)
CA (1) CA2163095A1 (fr)
WO (1) WO1994026274A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0859777T3 (da) * 1995-10-13 2007-09-03 Neurosearch As 8-azabicyclo[3.2.1]oct-2-en-derivater, deres fremstilling og anvendelse
US7105678B2 (en) 1995-11-03 2006-09-12 Organix, Inc. Boat tropanes
CA2721484A1 (fr) * 1999-05-12 2000-11-12 President And Fellows Of Harvard College Agents d'imagerie pour transporteur de dopamine
GB9920074D0 (en) * 1999-08-24 1999-10-27 Babraham Inst Animal model and uses thereof
US7459464B2 (en) * 2002-05-30 2008-12-02 Neurosearch A/S Triple monoamine reuptake inhibitors for the treatment of chronic pain
WO2007028770A1 (fr) * 2005-09-05 2007-03-15 Neurosearch A/S Inhibiteurs du recaptage du neurotransmetteur monoamine pour une neuroprotection chez des patients souffrant d'une maladie mentale avancée

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU668721B2 (en) * 1992-03-13 1996-05-16 Wake Forest University Biologically active tropane derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3813404A (en) * 1972-11-15 1974-05-28 Sterling Drug Inc Tropane-2-carboxylates and derivatives
US5288872A (en) * 1992-03-13 1994-02-22 Wake Forest University Compounds for treatment of neurodegenerative diseases
AU672052B2 (en) * 1992-12-23 1996-09-19 Neurosearch A/S Antidepressant and antiparkinsonian compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU668721B2 (en) * 1992-03-13 1996-05-16 Wake Forest University Biologically active tropane derivatives

Also Published As

Publication number Publication date
CA2163095A1 (fr) 1994-11-24
EP0697871A4 (fr) 1998-04-22
JPH08510238A (ja) 1996-10-29
WO1994026274A1 (fr) 1994-11-24
AU6767194A (en) 1994-12-12
EP0697871A1 (fr) 1996-02-28
JP2906085B2 (ja) 1999-06-14

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired