AU670435B2 - 4-iminoquinolines, processes for their preparation, and their use - Google Patents

4-iminoquinolines, processes for their preparation, and their use Download PDF

Info

Publication number
AU670435B2
AU670435B2 AU41492/93A AU4149293A AU670435B2 AU 670435 B2 AU670435 B2 AU 670435B2 AU 41492/93 A AU41492/93 A AU 41492/93A AU 4149293 A AU4149293 A AU 4149293A AU 670435 B2 AU670435 B2 AU 670435B2
Authority
AU
Australia
Prior art keywords
alkyl
alkoxy
chlorine
fluorine
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU41492/93A
Other languages
English (en)
Other versions
AU4149293A (en
Inventor
Rudolf Bender
Uta-Maria Billhardt-Troughton
Christoph Meichsner
Manfred Rosner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU4149293A publication Critical patent/AU4149293A/en
Application granted granted Critical
Publication of AU670435B2 publication Critical patent/AU670435B2/en
Assigned to AVENTIS PHARMA DEUTSCHLAND GMBH reassignment AVENTIS PHARMA DEUTSCHLAND GMBH Alteration of Name(s) in Register under S187 Assignors: HOECHST AKTIENGESELLSCHAFT
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
AU41492/93A 1992-06-27 1993-06-25 4-iminoquinolines, processes for their preparation, and their use Ceased AU670435B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4221210 1992-06-27
DE4221210 1992-06-27

Publications (2)

Publication Number Publication Date
AU4149293A AU4149293A (en) 1994-01-06
AU670435B2 true AU670435B2 (en) 1996-07-18

Family

ID=6462017

Family Applications (1)

Application Number Title Priority Date Filing Date
AU41492/93A Ceased AU670435B2 (en) 1992-06-27 1993-06-25 4-iminoquinolines, processes for their preparation, and their use

Country Status (19)

Country Link
US (1) US5602146A (OSRAM)
EP (1) EP0579968B1 (OSRAM)
JP (1) JP3605123B2 (OSRAM)
KR (1) KR940005577A (OSRAM)
CN (1) CN1083477A (OSRAM)
AT (1) ATE184003T1 (OSRAM)
AU (1) AU670435B2 (OSRAM)
CA (1) CA2099213C (OSRAM)
DE (1) DE59309756D1 (OSRAM)
DK (1) DK0579968T3 (OSRAM)
ES (1) ES2136628T3 (OSRAM)
GR (1) GR3031853T3 (OSRAM)
HU (1) HUT70040A (OSRAM)
IL (1) IL106147A (OSRAM)
MX (1) MX9303843A (OSRAM)
NZ (1) NZ247993A (OSRAM)
PH (1) PH31682A (OSRAM)
TW (1) TW304945B (OSRAM)
ZA (1) ZA934576B (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4344452A1 (de) * 1993-12-24 1995-06-29 Hoechst Ag Aza-4-iminochinoline, Verfahren zu ihrer Herstellung und ihre Verwendung
DE4428932A1 (de) * 1994-08-16 1996-02-22 Hoechst Ag Substituierte-Chinolinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19613591A1 (de) * 1996-04-04 1997-10-09 Hoechst Ag Substituierte-Chinolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
GB9930061D0 (en) * 1999-12-20 2000-02-09 Glaxo Group Ltd Quinolone compounds for use in treating viral infections
WO2004035577A2 (en) * 2002-10-16 2004-04-29 Gilead Sciences, Inc. Pre-organized tricyclic integrase inhibitor compounds
ATE411030T1 (de) * 2004-04-14 2008-10-15 Gilead Sciences Inc Phosphonatanaloga von hiv- integrasehemmerverbindungen
WO2008090640A1 (ja) * 2007-01-23 2008-07-31 Fujifilm Corporation オキシム化合物、感光性組成物、カラーフィルタ及びその製造方法、並びに液晶表示素子
JP5305704B2 (ja) * 2008-03-24 2013-10-02 富士フイルム株式会社 新規化合物、光重合性組成物、カラーフィルタ用光重合性組成物、カラーフィルタ、及びその製造方法、固体撮像素子、並びに、平版印刷版原版
JP6483382B2 (ja) * 2014-09-16 2019-03-13 株式会社Adeka 感光性樹脂組成物、その硬化物
JP6734416B2 (ja) * 2019-02-13 2020-08-05 株式会社Adeka 新規化合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US758568A (en) * 1903-05-29 1904-04-26 William E Snediker Wrench.
US4985439A (en) * 1985-11-21 1991-01-15 Anheuser-Busch Companies, Inc. Glucose tolerance factor and method of making same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79603B (OSRAM) * 1982-07-24 1984-10-31 Pfizer
WO1987003200A1 (en) * 1985-11-21 1987-06-04 Anheuser-Busch Companies, Inc. Glucose tolerance factor and method of making same
US5192768A (en) 1990-09-14 1993-03-09 Kyowa Hakko Kogyo Co., Ltd. Pyrazoloquinoline derivatives
PT509398E (pt) * 1991-04-15 2002-02-28 Aventis Pharma Gmbh Quinoxalinas processo para a sua preparacao e sua utilizacao

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US758568A (en) * 1903-05-29 1904-04-26 William E Snediker Wrench.
US4985439A (en) * 1985-11-21 1991-01-15 Anheuser-Busch Companies, Inc. Glucose tolerance factor and method of making same

Also Published As

Publication number Publication date
US5602146A (en) 1997-02-11
EP0579968A1 (de) 1994-01-26
ES2136628T3 (es) 1999-12-01
IL106147A0 (en) 1993-10-20
DK0579968T3 (da) 2000-03-27
PH31682A (en) 1999-01-18
ATE184003T1 (de) 1999-09-15
IL106147A (en) 1997-06-10
HU9301875D0 (en) 1993-09-28
GR3031853T3 (en) 2000-02-29
HUT70040A (en) 1995-09-28
NZ247993A (en) 1995-11-27
MX9303843A (es) 1994-01-31
CA2099213A1 (en) 1993-12-28
EP0579968B1 (de) 1999-09-01
CA2099213C (en) 2005-11-29
TW304945B (OSRAM) 1997-05-11
CN1083477A (zh) 1994-03-09
JPH0673012A (ja) 1994-03-15
ZA934576B (en) 1994-01-31
KR940005577A (ko) 1994-03-21
JP3605123B2 (ja) 2004-12-22
AU4149293A (en) 1994-01-06
DE59309756D1 (de) 1999-10-07

Similar Documents

Publication Publication Date Title
DE4344452A1 (de) Aza-4-iminochinoline, Verfahren zu ihrer Herstellung und ihre Verwendung
AU2002313410B2 (en) Hepatitis C virus polymerase inhibitors with a heterobicyclic structure
CA2966759C (en) Heterocyclic derivatives for treating diseases associated with activation of stat3 protein
AU654178B2 (en) Quinoxalines, processes for their preparation, and their use
HUT65302A (en) Azaquinoxaline- derivatives with antiviral effect and process for the production of these compounds and of pharmaceutical preparatives containing it
KR20180098573A (ko) Pad4의 아자-벤즈이미다졸 억제제
WO2012173448A2 (ko) 인다논 유도체, 이의 약학적으로 허용되는 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 바이러스성 질환의 예방 또는 치료용 약학적 조성물
KR20050093826A (ko) 히스톤 디아세틸라제 (ｈｄａｃ) 저해제로서의히드록사미드 산 유도체
US6369057B1 (en) Quinoxalines, processes for their preparation and their use
US5602146A (en) 4-iminoquinolines, processes for their preparation, and their use
US6114349A (en) Substituted quinoline derivatives with antiviral action
AU710238B2 (en) Substituted quinoline derivatives, a process for their preparation, and their use
DE4342024A1 (de) Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid
GB2282808A (en) 3-substituted heterocyclic indoles as inhibitors of HIV reverse transcriptase
CN101896492B (zh) 四环双吡喃香豆素化合物及其抗hiv和抗结核菌用途
WO2003103599A2 (en) Caspase-1 inhibitors and methods for their use
ZA200400240B (en) Viral polymerase inhibitors.
CA2957566A1 (en) Indoline sulfonamide inhibitors of dape and ndm-1 and use of the same

Legal Events

Date Code Title Description
PC Assignment registered

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH

Free format text: FORMER OWNER WAS: HOECHST AKTIENGESELLSCHAFT

MK14 Patent ceased section 143(a) (annual fees not paid) or expired