AU660875B2 - Apparatus for mixing and detecting on-line homogeneity - Google Patents
Apparatus for mixing and detecting on-line homogeneity Download PDFInfo
- Publication number
- AU660875B2 AU660875B2 AU65997/94A AU6599794A AU660875B2 AU 660875 B2 AU660875 B2 AU 660875B2 AU 65997/94 A AU65997/94 A AU 65997/94A AU 6599794 A AU6599794 A AU 6599794A AU 660875 B2 AU660875 B2 AU 660875B2
- Authority
- AU
- Australia
- Prior art keywords
- container
- support
- mixture
- mixing
- axle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000002156 mixing Methods 0.000 title claims abstract description 66
- 239000000203 mixture Substances 0.000 claims abstract description 135
- 239000008240 homogeneous mixture Substances 0.000 claims abstract description 33
- 238000000034 method Methods 0.000 claims abstract description 24
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract description 21
- 230000005855 radiation Effects 0.000 claims description 44
- 238000001514 detection method Methods 0.000 claims description 26
- 239000000835 fiber Substances 0.000 claims description 24
- 238000007789 sealing Methods 0.000 claims description 17
- 238000004891 communication Methods 0.000 claims description 13
- 230000008569 process Effects 0.000 claims description 10
- 239000000523 sample Substances 0.000 claims description 10
- 230000008878 coupling Effects 0.000 claims description 6
- 238000010168 coupling process Methods 0.000 claims description 6
- 238000005859 coupling reaction Methods 0.000 claims description 6
- 238000007599 discharging Methods 0.000 claims description 6
- 238000001069 Raman spectroscopy Methods 0.000 claims description 3
- 230000007246 mechanism Effects 0.000 claims description 2
- 230000001360 synchronised effect Effects 0.000 claims 1
- 238000001228 spectrum Methods 0.000 description 19
- 230000004888 barrier function Effects 0.000 description 10
- 239000007788 liquid Substances 0.000 description 7
- 239000013307 optical fiber Substances 0.000 description 7
- 238000004611 spectroscopical analysis Methods 0.000 description 7
- 238000004458 analytical method Methods 0.000 description 5
- 230000003595 spectral effect Effects 0.000 description 5
- 239000003814 drug Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 239000007884 disintegrant Substances 0.000 description 3
- 238000004128 high performance liquid chromatography Methods 0.000 description 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 2
- 239000004809 Teflon Substances 0.000 description 2
- 229920006362 Teflon® Polymers 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 230000000704 physical effect Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000010453 quartz Substances 0.000 description 2
- 238000005204 segregation Methods 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 239000008247 solid mixture Substances 0.000 description 2
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical compound FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 235000008247 Echinochloa frumentacea Nutrition 0.000 description 1
- 240000004072 Panicum sumatrense Species 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 229910052594 sapphire Inorganic materials 0.000 description 1
- 239000010980 sapphire Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012956 testing procedure Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000000870 ultraviolet spectroscopy Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/20—Mixers with rotating receptacles with receptacles rotating about an axis at an angle to their longitudinal axis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/40—Parts or components, e.g. receptacles, feeding or discharging means
- B01F29/401—Receptacles, e.g. provided with liners
- B01F29/4011—Receptacles, e.g. provided with liners characterised by the shape or cross-section of the receptacle, e.g. of Y-, Z -, S -, or X shape
- B01F29/40118—V or W shapes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/40—Parts or components, e.g. receptacles, feeding or discharging means
- B01F29/403—Disposition of the rotor axis
- B01F29/4036—Disposition of the rotor axis with a plurality of rotating receptacles
- B01F29/40363—Disposition of the rotor axis with a plurality of rotating receptacles having perpendicular axes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/60—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/60—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers
- B01F29/62—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers without bars, i.e. without mixing elements; characterised by the shape or cross section of the receptacle, e.g. of Y-, Z-, S- or X- shape; with cylindrical receptacles rotating about an axis at an angle to their longitudinal axis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/213—Measuring of the properties of the mixtures, e.g. temperature, density or colour
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/71705—Feed mechanisms characterised by the means for feeding the components to the mixer using belts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/75—Discharge mechanisms
- B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
- B01F35/7547—Discharge mechanisms characterised by the means for discharging the components from the mixer using valves, gates, orifices or openings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Geometry (AREA)
- Veterinary Medicine (AREA)
- Accessories For Mixers (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
- Continuous Casting (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8523093A | 1993-06-29 | 1993-06-29 | |
| US085230 | 1993-06-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU6599794A AU6599794A (en) | 1995-01-27 |
| AU660875B2 true AU660875B2 (en) | 1995-07-06 |
Family
ID=22190294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU65997/94A Ceased AU660875B2 (en) | 1993-06-29 | 1994-06-27 | Apparatus for mixing and detecting on-line homogeneity |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0631810B1 (es) |
| JP (1) | JP2650619B2 (es) |
| KR (1) | KR0162110B1 (es) |
| CN (1) | CN1062490C (es) |
| AT (1) | ATE157905T1 (es) |
| AU (1) | AU660875B2 (es) |
| BR (1) | BR9402570A (es) |
| CA (1) | CA2126826C (es) |
| DE (1) | DE69405483T2 (es) |
| DK (1) | DK0631810T3 (es) |
| ES (1) | ES2106449T3 (es) |
| GR (1) | GR3025143T3 (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITBO940193A1 (it) * | 1994-05-06 | 1995-11-06 | Corob Srl | Dispositivo di miscelazione di pitture, vernici e prodotti fluidi in generale e procedimento per il suo controllo. |
| US5504332A (en) * | 1994-08-26 | 1996-04-02 | Merck & Co., Inc. | Method and system for determining the homogeneity of tablets |
| EP0706040A1 (en) * | 1994-10-07 | 1996-04-10 | Bp Chemicals S.N.C. | Property determination |
| EP0706049A1 (en) * | 1994-10-07 | 1996-04-10 | Bp Chemicals S.N.C. | Cracking property determination |
| EP0706050A1 (en) * | 1994-10-07 | 1996-04-10 | Bp Chemicals S.N.C. | Lubricant property determination |
| EP0706041A1 (en) * | 1994-10-07 | 1996-04-10 | Bp Chemicals S.N.C. | Chemicals property determination |
| EP0801298B1 (en) * | 1996-04-09 | 2006-06-21 | Innovene Europe Limited | Control of process |
| IT232075Y1 (it) * | 1994-10-11 | 1999-08-16 | Corob Srl | Miscelatore di prodotti generalmente collocati in contenitori e gruppo di sostegno e serraggio per almeno uno di tali contenitori, |
| DE69631872D1 (de) * | 1996-04-09 | 2004-04-22 | Eutech Engineering Solutions L | Prozess-Steuerung |
| SE9802690D0 (sv) * | 1998-08-07 | 1998-08-07 | Astra Ab | Mixing apparatus |
| GB0003641D0 (en) * | 2000-02-17 | 2000-04-05 | Astrazeneca Uk Ltd | Mixing apparatus and method |
| SE0000522D0 (sv) * | 2000-02-17 | 2000-02-17 | Astrazeneca Ab | Mixing apparatus |
| CA2664171A1 (en) * | 2000-02-17 | 2001-08-23 | Ali Mohammed Afnan | Mixing apparatus and method |
| EP1497629A1 (en) | 2002-04-25 | 2005-01-19 | Glaxo Group Limited | Magnetoacoustic sensor system and associated method for sensing environmental conditions |
| DE102007014844B3 (de) * | 2007-03-28 | 2008-06-05 | Glatt Systemtechnik Gmbh | Verfahren zur Überwachung der optischen Durchlässigkeit eines Beobachtungsfensters und Einrichtung zur Reinigung eines Beobachtungsfensters |
| JP2009247999A (ja) * | 2008-04-07 | 2009-10-29 | Nisshin Engineering Co Ltd | 混合装置 |
| EP2431729A1 (en) * | 2010-01-15 | 2012-03-21 | Malvern Instruments Limited | Spectrometric characterisation of heterogeneity |
| DE102011113880A1 (de) | 2011-09-22 | 2013-03-28 | Haver Engineering Gmbh | Pelletiereinrichtung und Verfahren |
| CN103657488A (zh) * | 2013-12-18 | 2014-03-26 | 常熟振氟新材料有限公司 | 新型v型混合机 |
| CN103940785A (zh) * | 2014-04-10 | 2014-07-23 | 江苏大学 | 一种基于透射和散射的混药浓度在线测量装置 |
| CN104596934A (zh) * | 2014-12-30 | 2015-05-06 | 浙江海洋学院 | 带有混合器的分光光度计 |
| CN106064034A (zh) * | 2016-07-04 | 2016-11-02 | 苏州北开生化设备有限公司 | 一种可自控的真空v型混合机及其使用方法 |
| CN106268456A (zh) * | 2016-08-26 | 2017-01-04 | 天津市金桥焊材集团有限公司 | 一种药粉混合装置 |
| CN107824098B (zh) * | 2017-11-23 | 2024-01-19 | 广东嘉俊陶瓷有限公司 | 基料搅拌机构 |
| CN108267565B (zh) * | 2018-01-03 | 2022-03-11 | 西南石油大学 | 一种检测稠油稀油混合均匀程度及混合后发生二次分离的装置及方法 |
| CN108854656A (zh) * | 2018-05-03 | 2018-11-23 | 柳伟军 | 一种石油提炼催化剂沸石分子筛生产用原料混合机 |
| CN109012376B (zh) * | 2018-08-10 | 2021-06-29 | 昆明理工大学 | 一种高通量高效混粉机 |
| CN109569358A (zh) * | 2018-12-19 | 2019-04-05 | 长沙凯天工研院环保服务有限公司 | 在线近红外光谱监测土壤稳定化过程的搅拌装备 |
| CN110411978B (zh) * | 2019-07-26 | 2020-05-22 | 中国农业大学 | 一种物料均匀性检测设备及检测方法 |
| CN113203827B (zh) * | 2020-03-03 | 2023-09-29 | 大唐环境产业集团股份有限公司 | 一种多路抽样混合搅拌测量NOx的方法及装置 |
| CN112206711B (zh) * | 2020-09-10 | 2022-06-17 | 佛山科学技术学院 | 一种试剂混匀状态检测方法、装置及系统 |
| CN112206702A (zh) * | 2020-09-27 | 2021-01-12 | 重庆航天工业有限公司 | 一种自动混合装置与系统 |
| CN112588157B (zh) * | 2020-11-20 | 2023-12-12 | 湖南开磷雁峰塔涂料有限公司 | 一种防腐涂料用混匀搅拌设备 |
| CN112717838B (zh) * | 2020-12-30 | 2022-07-26 | 山东鑫生工贸有限公司 | 一种旋转反应催化装置 |
| CN112871002A (zh) * | 2021-01-12 | 2021-06-01 | 长飞光纤光缆股份有限公司 | 一种多组分粉体原料的匀混方法 |
| CN114471275A (zh) * | 2021-12-30 | 2022-05-13 | 西安近代化学研究所 | 一种混同滚筒、药料混同检测设备、方法及应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1982003342A1 (en) * | 1981-04-06 | 1982-10-14 | Corp Pettibone | Mixing equipment and agitator therefor for use with granular material and method of producing prepared granular material |
| US4752131A (en) * | 1984-04-04 | 1988-06-21 | Basf Aktiengesellschaft | Laser-optical arrangement for measuring the degree of dispersion in flowing systems |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB590441A (en) * | 1945-04-18 | 1947-07-17 | Sidney Tyler | Improvements relating to blending apparatus of the rotary drum mixer type |
| US2514126A (en) * | 1949-12-08 | 1950-07-04 | Patterson Kelley Co | Blending or mixing apparatus |
| DE1905290A1 (de) * | 1969-02-04 | 1970-10-01 | Dynamit Nobel Ag | Drehdurchfuehrung an rotierenden Behaeltern |
| GB1386312A (en) * | 1972-10-30 | 1975-03-05 | Inoue Japax Res | Manufacture of settable dental compositions |
| GB1545538A (en) * | 1975-11-17 | 1979-05-10 | Gradient Pty Ltd | Method and apparatus for simultaneously recording reaction times |
| JPS54127065A (en) * | 1978-03-22 | 1979-10-02 | Kubota Ltd | Position control device of mixer |
| DE3337403A1 (de) * | 1983-10-14 | 1985-05-02 | Seyd Fertigbeton Berlin, Zweigniederlassung der Readymix Transportbeton GmbH, 4030 Ratingen | Verfahren und vorrichtung zum herstellen von gemischen |
| JPS61230727A (ja) * | 1985-04-03 | 1986-10-15 | Nippon Paint Co Ltd | 分散装置 |
| SU1402856A1 (ru) * | 1985-12-13 | 1988-06-15 | Ивановский государственный университет | Устройство дл приготовлени термохромных композиций и измерени их цветотемпературных характеристик |
| JPH02273535A (ja) * | 1989-04-13 | 1990-11-08 | Fujitsu Ltd | ガス流量制御装置 |
| GB2252259A (en) * | 1990-12-19 | 1992-08-05 | Unilever Plc | Controlling process for producing dispersions |
| JPH0516134A (ja) * | 1991-06-06 | 1993-01-26 | Yokohama Rubber Co Ltd:The | 密閉式混合機の制御方法及びその装置 |
-
1994
- 1994-06-03 EP EP94304010A patent/EP0631810B1/en not_active Expired - Lifetime
- 1994-06-03 ES ES94304010T patent/ES2106449T3/es not_active Expired - Lifetime
- 1994-06-03 DE DE69405483T patent/DE69405483T2/de not_active Expired - Fee Related
- 1994-06-03 DK DK94304010.5T patent/DK0631810T3/da active
- 1994-06-03 AT AT94304010T patent/ATE157905T1/de not_active IP Right Cessation
- 1994-06-23 JP JP6141356A patent/JP2650619B2/ja not_active Expired - Fee Related
- 1994-06-27 AU AU65997/94A patent/AU660875B2/en not_active Ceased
- 1994-06-27 CA CA002126826A patent/CA2126826C/en not_active Expired - Fee Related
- 1994-06-28 BR BR9402570A patent/BR9402570A/pt not_active Application Discontinuation
- 1994-06-28 KR KR1019940014952A patent/KR0162110B1/ko not_active IP Right Cessation
- 1994-06-28 CN CN94107246A patent/CN1062490C/zh not_active Expired - Fee Related
-
1997
- 1997-10-22 GR GR970402775T patent/GR3025143T3/el unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1982003342A1 (en) * | 1981-04-06 | 1982-10-14 | Corp Pettibone | Mixing equipment and agitator therefor for use with granular material and method of producing prepared granular material |
| US4752131A (en) * | 1984-04-04 | 1988-06-21 | Basf Aktiengesellschaft | Laser-optical arrangement for measuring the degree of dispersion in flowing systems |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0768146A (ja) | 1995-03-14 |
| ATE157905T1 (de) | 1997-09-15 |
| DK0631810T3 (da) | 1997-10-20 |
| DE69405483T2 (de) | 1998-01-15 |
| GR3025143T3 (en) | 1998-02-27 |
| JP2650619B2 (ja) | 1997-09-03 |
| EP0631810A1 (en) | 1995-01-04 |
| EP0631810B1 (en) | 1997-09-10 |
| CA2126826A1 (en) | 1994-12-30 |
| AU6599794A (en) | 1995-01-27 |
| CN1100002A (zh) | 1995-03-15 |
| ES2106449T3 (es) | 1997-11-01 |
| KR950001299A (ko) | 1995-01-03 |
| BR9402570A (pt) | 1995-04-11 |
| DE69405483D1 (de) | 1997-10-16 |
| KR0162110B1 (ko) | 1998-11-16 |
| CN1062490C (zh) | 2001-02-28 |
| CA2126826C (en) | 1999-02-23 |
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