AU659505B2 - Cyclic peroxyacetal compounds - Google Patents

Cyclic peroxyacetal compounds Download PDF

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Publication number
AU659505B2
AU659505B2 AU27672/92A AU2767292A AU659505B2 AU 659505 B2 AU659505 B2 AU 659505B2 AU 27672/92 A AU27672/92 A AU 27672/92A AU 2767292 A AU2767292 A AU 2767292A AU 659505 B2 AU659505 B2 AU 659505B2
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AU
Australia
Prior art keywords
formula
compound
document
ring oxygen
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU27672/92A
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English (en)
Other versions
AU2767292A (en
Inventor
Richard Kingston Haynes
Simone Charlotte Vonwiller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SYDNEY THE, University of
Original Assignee
University of Sydney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Sydney filed Critical University of Sydney
Priority to AU27672/92A priority Critical patent/AU659505B2/en
Publication of AU2767292A publication Critical patent/AU2767292A/en
Application granted granted Critical
Publication of AU659505B2 publication Critical patent/AU659505B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/05—Alcohols containing rings other than six-membered aromatic rings
    • C07C33/14—Alcohols containing rings other than six-membered aromatic rings containing six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/38—Alcohols containing six-membered aromatic rings and other rings and having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/225—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/527—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings
    • C07C49/553—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymerization Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU27672/92A 1991-10-14 1992-10-14 Cyclic peroxyacetal compounds Ceased AU659505B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU27672/92A AU659505B2 (en) 1991-10-14 1992-10-14 Cyclic peroxyacetal compounds

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPK8875 1991-10-14
AUPK887591 1991-10-14
AU27672/92A AU659505B2 (en) 1991-10-14 1992-10-14 Cyclic peroxyacetal compounds
PCT/AU1992/000548 WO1993008195A1 (en) 1991-10-14 1992-10-14 Cyclic peroxyacetal compounds

Publications (2)

Publication Number Publication Date
AU2767292A AU2767292A (en) 1993-05-21
AU659505B2 true AU659505B2 (en) 1995-05-18

Family

ID=3775744

Family Applications (1)

Application Number Title Priority Date Filing Date
AU27672/92A Ceased AU659505B2 (en) 1991-10-14 1992-10-14 Cyclic peroxyacetal compounds

Country Status (3)

Country Link
JP (1) JPH07500325A (ja)
AU (1) AU659505B2 (ja)
WO (1) WO1993008195A1 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6160004A (en) * 1997-12-30 2000-12-12 Hauser, Inc. C-10 carbon-substituted artemisinin-like trioxane compounds having antimalarial, antiproliferative and antitumor activities
US6156790A (en) * 1997-12-30 2000-12-05 Hauser, Inc. C-10 carbon-substituted artemisinin-like trioxane compounds having antimalarial, antiproliferative and antitumor activities
WO2000004026A1 (en) * 1998-07-14 2000-01-27 The Hong Kong University Of Science & Technology Trioxane derivatives
NZ509324A (en) * 1998-07-14 2003-07-25 Bayer Ag Antiparasitic artemisinin derivatives (endoperoxides)
WO2000004025A1 (en) * 1998-07-14 2000-01-27 The Hong Kong University Of Science & Technology Antiparasitic artemisinin derivatives (endoperoxides)
US6297272B1 (en) 1999-01-12 2001-10-02 Hauser, Inc. Artemisinin analogs having antimalarial antiproliferative and antitumor activities and chemoselective methods of making the same
JP3418724B2 (ja) * 2000-02-10 2003-06-23 国立医薬品食品衛生研究所長 セスキテルペノイド化合物及びそれを含む医薬
KR100529600B1 (ko) 2003-01-23 2005-11-22 정만길 디옥소아테미시닌 유사체, 그의 제조방법 및 그를포함하는 항암제

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988004660A2 (en) * 1986-12-18 1988-06-30 Sri International Synthesis process and oxygen-containing heterocyclic products thereof
AU4242189A (en) * 1988-10-04 1990-04-12 Hoechst A.G. Novel artemisinin derivatives, processes for their preparation and their use as antiprotozoal agents
AU7618591A (en) * 1990-05-07 1991-11-07 Hoechst Aktiengesellschaft 9-substituted compounds of 3 alpha, 11 alpha-epoxy-3,4,5,5a alpha,6,7,8,8a,9,11, 11a undecahydro-3 beta,6 alpa, 9-trimethylfurano(3,4-j)(1,2)-benzodioxepin, processes for their preparation and their use as antiprotozoal and antiviral agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916204A (en) * 1987-07-31 1990-04-10 Massachusetts Institute Of Technology Pure polyanhydride from dicarboxylic acid and coupling agent
AU640171B2 (en) * 1989-09-27 1993-08-19 Rhone-Poulenc Rorer S.A. Cyclic peroxyacetal lactone, lactol and ether compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988004660A2 (en) * 1986-12-18 1988-06-30 Sri International Synthesis process and oxygen-containing heterocyclic products thereof
AU4242189A (en) * 1988-10-04 1990-04-12 Hoechst A.G. Novel artemisinin derivatives, processes for their preparation and their use as antiprotozoal agents
AU7618591A (en) * 1990-05-07 1991-11-07 Hoechst Aktiengesellschaft 9-substituted compounds of 3 alpha, 11 alpha-epoxy-3,4,5,5a alpha,6,7,8,8a,9,11, 11a undecahydro-3 beta,6 alpa, 9-trimethylfurano(3,4-j)(1,2)-benzodioxepin, processes for their preparation and their use as antiprotozoal and antiviral agents

Also Published As

Publication number Publication date
JPH07500325A (ja) 1995-01-12
AU2767292A (en) 1993-05-21
WO1993008195A1 (en) 1993-04-29

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