AU658594B2 - Heparin derivatives - Google Patents

Heparin derivatives

Info

Publication number
AU658594B2
AU658594B2 AU90964/91A AU9096491A AU658594B2 AU 658594 B2 AU658594 B2 AU 658594B2 AU 90964/91 A AU90964/91 A AU 90964/91A AU 9096491 A AU9096491 A AU 9096491A AU 658594 B2 AU658594 B2 AU 658594B2
Authority
AU
Australia
Prior art keywords
heparin
process according
salts
molecular weight
heparin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU90964/91A
Other languages
English (en)
Other versions
AU9096491A (en
Inventor
Francesco Della Valle
Gunter Kirschner
Aurelio Romeo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia SpA filed Critical Fidia SpA
Publication of AU9096491A publication Critical patent/AU9096491A/en
Application granted granted Critical
Publication of AU658594B2 publication Critical patent/AU658594B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
AU90964/91A 1990-12-20 1991-12-20 Heparin derivatives Ceased AU658594B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT41752/90 1990-12-20
IT04175290A IT1243300B (it) 1990-12-20 1990-12-20 Derivati dell'eparina
PCT/EP1991/002479 WO1992011294A1 (fr) 1990-12-20 1991-12-20 Derives d'heparine

Publications (2)

Publication Number Publication Date
AU9096491A AU9096491A (en) 1992-07-22
AU658594B2 true AU658594B2 (en) 1995-04-27

Family

ID=11253436

Family Applications (1)

Application Number Title Priority Date Filing Date
AU90964/91A Ceased AU658594B2 (en) 1990-12-20 1991-12-20 Heparin derivatives

Country Status (13)

Country Link
EP (1) EP0516792A1 (fr)
JP (1) JPH05504785A (fr)
KR (1) KR920703644A (fr)
CN (1) CN1062537A (fr)
AU (1) AU658594B2 (fr)
BR (1) BR9106234A (fr)
CA (1) CA2075970A1 (fr)
FI (1) FI923762A (fr)
HU (1) HUT62917A (fr)
IT (1) IT1243300B (fr)
NO (1) NO923240L (fr)
PT (1) PT99898A (fr)
WO (1) WO1992011294A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2663639B1 (fr) * 1990-06-26 1994-03-18 Rhone Poulenc Sante Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
FR2704861B1 (fr) * 1993-05-07 1995-07-28 Sanofi Elf Fractions d'héparine purifiées, procédé d'obtention et compositions pharmaceutiques les contenant.
ES2077533B1 (es) * 1994-02-28 1996-07-01 Bioiberica Procedimiento de obtencion de fracciones de oligosacaridos por despolimerizacion quimica de heparina.
US5639469A (en) * 1994-06-15 1997-06-17 Minnesota Mining And Manufacturing Company Transmucosal delivery system
US6001820A (en) * 1995-03-31 1999-12-14 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US5763427A (en) * 1995-03-31 1998-06-09 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US5744457A (en) * 1995-03-31 1998-04-28 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US6482806B1 (en) * 1996-03-15 2002-11-19 Takara Shuzo Co., Ltd. Product of heat treatment of uronic acid, food, drink, or drug including the product
US5767269A (en) * 1996-10-01 1998-06-16 Hamilton Civic Hospitals Research Development Inc. Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
FR2763848B1 (fr) 1997-05-28 2000-01-28 Rhone Poulenc Rorer Sa Utilisation des heparines de bas poids moleculaire pour la prevention et le traitement du trauma du systeme nerveux central
DE10217557A1 (de) * 2002-04-19 2003-11-06 Degussa Bioactives Gmbh Funktionsnahrungsmittel enthaltend eine Phospholipid-haltige stabile Matrix
WO2003088949A2 (fr) * 2002-04-19 2003-10-30 Bioghurt Biogarde Gmbh & Co. Kg. Matrice a constituant bioactif contenant des phospholipides
CN100335506C (zh) * 2004-05-20 2007-09-05 汕头市金丰医疗器械科技有限公司 一种肝素化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2482603A1 (fr) * 1980-05-14 1981-11-20 Pharmindustrie Nouveaux esters d'heparine utilisables pour la preparation de medicaments, et procedes pour leur preparation
ES2071608T3 (es) * 1986-08-20 1995-07-01 Univ Miami Esteres de alcanoilo de heparina de bajo peso molecular.
SE8702254D0 (sv) * 1987-05-29 1987-05-29 Kabivitrum Ab Novel heparin derivatives

Also Published As

Publication number Publication date
EP0516792A1 (fr) 1992-12-09
NO923240D0 (no) 1992-08-18
FI923762A0 (fi) 1992-08-20
IT1243300B (it) 1994-05-26
NO923240L (no) 1992-10-19
AU9096491A (en) 1992-07-22
IT9041752A1 (it) 1992-06-21
CA2075970A1 (fr) 1992-06-21
CN1062537A (zh) 1992-07-08
BR9106234A (pt) 1993-03-30
KR920703644A (ko) 1992-12-18
PT99898A (pt) 1992-12-31
WO1992011294A1 (fr) 1992-07-09
FI923762A (fi) 1992-08-20
HUT62917A (en) 1993-06-28
IT9041752A0 (it) 1990-12-20
JPH05504785A (ja) 1993-07-22

Similar Documents

Publication Publication Date Title
US5250519A (en) Non-anticoagulant heparin derivatives
DK173982B1 (da) Depolymeriserede heparinderivater, fremgangsmåde til fremstilling deraf og farmaceutisk præparat samt biologisk reagens med indhold heraf
AU658594B2 (en) Heparin derivatives
AU1763892A (en) New non-anticoagulant heparin derivatives
US5032679A (en) Heparin fragments as inhibitors of smooth muscle cell proliferation
US20190030066A1 (en) Antithrombin-heparin compositions and methods
EP1070503B1 (fr) Compositions contenant de l'héparin à bas poids moleculaire
NZ214094A (en) Xylan sulphates of low molecular weight, process for their preparation and medicaments containing them
CA2198908A1 (fr) Methode de regulation de la o-desulfatation de l'heparine et des compositions qui en decoulent
EP0862585A1 (fr) Procede de regulation de la o-desulfatation de l'heparine et compositions produites par ce procede
AU2435795A (en) O-desulfated heparin derivatives, methods of making and uses thereof
US10494452B2 (en) Low-molecular-weight glycosaminoglycan derivative containing terminal 2, 5-anhydrated talose or derivative thereof
US20240041918A1 (en) Oligosaccharide Compound for Inhibiting Intrinsic Coagulation Factor X-Enzyme Complex, and Preparation Method Therefor and Uses Thereof
KR20210151798A (ko) 콘드로이틴 설페이트 다당류, 이의 반합성 제조방법 및 이의 용도
PT91249B (pt) Processo para a preparacao de glicosaminoglicanos selectivamente o-acilados
JPS6357407B2 (fr)
CN111423523B (zh) 一种寡糖化合物及其药学上可接受的盐、制备方法及应用
WO1994008595A1 (fr) Utilisation d'heparine non anticoagulante dans le traitement des lesions ischemiques et consecutives a une perfusion
EP0380719A1 (fr) Héparines modifiées et procédé de préparation
US20060069044A1 (en) Modified glycosaminoglycans, pharmaceutical compositions and methods for oral delivery thereof