AU658148B2 - Use of radioactive metal ion complexes with all-cis-1,3,5-triamino-2,4,6-cyclohexantriol and their derivates for x-ray diagnosis and in tumor therapy as well asfor producing x-ray diagnostic and tumor therapy agents - Google Patents

Use of radioactive metal ion complexes with all-cis-1,3,5-triamino-2,4,6-cyclohexantriol and their derivates for x-ray diagnosis and in tumor therapy as well asfor producing x-ray diagnostic and tumor therapy agents Download PDF

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Publication number
AU658148B2
AU658148B2 AU84367/91A AU8436791A AU658148B2 AU 658148 B2 AU658148 B2 AU 658148B2 AU 84367/91 A AU84367/91 A AU 84367/91A AU 8436791 A AU8436791 A AU 8436791A AU 658148 B2 AU658148 B2 AU 658148B2
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AU
Australia
Prior art keywords
die
alkyl groups
der
alkyl
document
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU84367/91A
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English (en)
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AU8436791A (en
Inventor
Isidor Erni
Peter Geisser
Hans Kaspar Heggetschweiler
Walter Schneider
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vifor International AG
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Laboratorien Hausmann AG
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Publication of AU8436791A publication Critical patent/AU8436791A/en
Application granted granted Critical
Publication of AU658148B2 publication Critical patent/AU658148B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU84367/91A 1990-09-05 1991-09-05 Use of radioactive metal ion complexes with all-cis-1,3,5-triamino-2,4,6-cyclohexantriol and their derivates for x-ray diagnosis and in tumor therapy as well asfor producing x-ray diagnostic and tumor therapy agents Ceased AU658148B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4028139A DE4028139A1 (de) 1990-09-05 1990-09-05 Verwendung der komplexe radioaktiver metallionen mit all-cis-1,3,5-triamino-2,4,6-cyclohexantriol und seinen derivaten fuer roentgendiagnostische zwecke und in der tumortherapie sowie zur herstellung von mitteln fuer roentgendiagnostische zwecke und fuer die tumortherapie
DE4028139 1990-09-05
PCT/EP1991/001679 WO1992004056A1 (de) 1990-09-05 1991-09-05 VERWENDUNG DER KOMPLEXE RADIOAKTIVER METALLIONEN MIT all-cis-1,3,5-TRIAMINO-2,4,6-CYCLOHEXANTRIOL UND SEINEN DERIVATEN FÜR RÖNTGENDIAGNOSTISCHE ZWECKE UND IN DER TUMORTHERAPIE SOWIE ZUR HERSTELLUNG VON MITTELN FÜR RÖNTGENDIAGNOSTISCHE ZWECKE UND FÜR DIE TUMORTHERAPIE

Publications (2)

Publication Number Publication Date
AU8436791A AU8436791A (en) 1992-03-30
AU658148B2 true AU658148B2 (en) 1995-04-06

Family

ID=6413642

Family Applications (1)

Application Number Title Priority Date Filing Date
AU84367/91A Ceased AU658148B2 (en) 1990-09-05 1991-09-05 Use of radioactive metal ion complexes with all-cis-1,3,5-triamino-2,4,6-cyclohexantriol and their derivates for x-ray diagnosis and in tumor therapy as well asfor producing x-ray diagnostic and tumor therapy agents

Country Status (10)

Country Link
EP (1) EP0504339A1 (ko)
JP (1) JPH05502456A (ko)
KR (1) KR920702235A (ko)
AU (1) AU658148B2 (ko)
CA (1) CA2073050A1 (ko)
DE (1) DE4028139A1 (ko)
MX (1) MX9100967A (ko)
PT (1) PT98869A (ko)
TW (1) TW197951B (ko)
WO (1) WO1992004056A1 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830430A (en) 1995-02-21 1998-11-03 Imarx Pharmaceutical Corp. Cationic lipids and the use thereof
EP2849804A1 (en) * 2012-05-18 2015-03-25 Bayer Pharma Aktiengesellschaft Bis azainositol heavy metal complexes for x-ray imaging
EP2796152A1 (en) * 2013-04-25 2014-10-29 Bayer Pharma Aktiengesellschaft Unsymmetrical Bis Azainositol Hafnium Complexes for X-Ray Imaging
EP2873670A1 (en) 2013-11-14 2015-05-20 Bayer Pharma Aktiengesellschaft Bis azainositol zirconium complexes for X-ray imaging

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190676A1 (de) * 1985-02-02 1986-08-13 Laboratorien Hausmann AG All-cis-1,3,5-Triamino2,4,6-cyclohexantriol-Derivate, ihre Verwendung, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8900719D0 (en) * 1989-01-13 1989-03-08 Nycomed As Compounds
CH679742A5 (ko) * 1990-01-09 1992-04-15 Byk Gulden Lomberg Chem Fab

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190676A1 (de) * 1985-02-02 1986-08-13 Laboratorien Hausmann AG All-cis-1,3,5-Triamino2,4,6-cyclohexantriol-Derivate, ihre Verwendung, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
AU8436791A (en) 1992-03-30
CA2073050A1 (en) 1992-03-06
JPH05502456A (ja) 1993-04-28
WO1992004056A1 (de) 1992-03-19
PT98869A (pt) 1992-07-31
DE4028139A1 (de) 1992-03-12
TW197951B (ko) 1993-01-11
EP0504339A1 (de) 1992-09-23
KR920702235A (ko) 1992-09-03
MX9100967A (es) 1992-05-04

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