AU651976B2 - Novel synthetic GRF analogs - Google Patents
Novel synthetic GRF analogsInfo
- Publication number
- AU651976B2 AU651976B2 AU78822/91A AU7882291A AU651976B2 AU 651976 B2 AU651976 B2 AU 651976B2 AU 78822/91 A AU78822/91 A AU 78822/91A AU 7882291 A AU7882291 A AU 7882291A AU 651976 B2 AU651976 B2 AU 651976B2
- Authority
- AU
- Australia
- Prior art keywords
- ala
- peptide
- leu
- composition
- grf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Luminescent Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51905490A | 1990-05-04 | 1990-05-04 | |
| US519054 | 1990-05-04 | ||
| PCT/US1991/003053 WO1991016923A1 (fr) | 1990-05-04 | 1991-04-30 | Nouveaux analogues grf synthetiques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7882291A AU7882291A (en) | 1991-11-27 |
| AU651976B2 true AU651976B2 (en) | 1994-08-11 |
Family
ID=24066591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU78822/91A Expired - Fee Related AU651976B2 (en) | 1990-05-04 | 1991-04-30 | Novel synthetic GRF analogs |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0527914A4 (fr) |
| JP (1) | JPH06502618A (fr) |
| AU (1) | AU651976B2 (fr) |
| CA (1) | CA2082059A1 (fr) |
| WO (1) | WO1991016923A1 (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5262519A (en) * | 1991-05-15 | 1993-11-16 | The Salk Institute For Biological Studies | GRF analogs XI |
| WO1994011396A1 (fr) * | 1992-11-13 | 1994-05-26 | The Administrators Of The Tulane Educational Fund | Agonistes de l'hormone de liberation de l'hormone de croissance |
| WO1994011397A1 (fr) * | 1992-11-13 | 1994-05-26 | The Administrators Of The Tulane Educational Fund | Agonistes de somatostatine |
| US5550212A (en) * | 1993-12-17 | 1996-08-27 | The Administrators Of The Tulane Educational Fund | Analogues of hGH-RH(1-29)NH2 having antagonistic activity |
| US6184208B1 (en) | 1994-06-29 | 2001-02-06 | Immunotech Developments Inc. | Peptide, a method for its preparation and a pharmaceutical composition containing the peptide |
| CA2158782C (fr) * | 1994-09-23 | 2010-01-12 | Pierrette Gaudreau | Marqueur pour recepteurs de facteurs liberant des hormones de croissance |
| WO1996032126A1 (fr) * | 1995-04-14 | 1996-10-17 | The Administrators Of The Tulane Educational Fund | Analogues du facteur liberant l'hormone de croissance |
| US6458764B1 (en) * | 1995-05-26 | 2002-10-01 | Theratechnologies Inc. | GRF analogs with increased biological potency |
| US5942489A (en) * | 1996-05-03 | 1999-08-24 | The Administrators Of The Tulane Educational Fund | HGH-RH(1-29)NH2 analogues having antagonistic activity |
| US6057422A (en) * | 1998-11-25 | 2000-05-02 | The Administrators Of The Tulane Educational Fund | Antagonistic analogs of GH-RH inhibiting IGF-I and -II |
| MX2010010642A (es) * | 2008-03-28 | 2011-03-29 | The Univ Of Miami | Nuevos analogos antagonistas, sustituidos, n- y c- terminales, de hormona liberadora de hormona de crecimiento (gh-rh). |
| US8691942B2 (en) | 2008-03-28 | 2014-04-08 | University Of Miami | N- and C- terminal substituted antagonistic analogs of GH-RH |
| US10240138B2 (en) | 2008-06-12 | 2019-03-26 | Ipsen Bioinnovation Limited | Polypeptides that bind to and inhibit secretion from growth hormone secreting cells |
| US20110171191A1 (en) | 2008-06-12 | 2011-07-14 | Syntaxin Limited | Suppression of neuroendocrine diseases |
| GB0820970D0 (en) | 2008-11-17 | 2008-12-24 | Syntaxin Ltd | Suppression of cancer |
| AU2020218272A1 (en) | 2019-02-08 | 2021-09-02 | United States Government As Represented By The Department Of Veterans Affairs | Growth hormone-releasing hormone antagonists and uses thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1996392A (en) * | 1991-05-15 | 1992-12-30 | Salk Institute For Biological Studies, The | Grf analogs xi |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4649131A (en) * | 1984-09-24 | 1987-03-10 | Hoffmann-La Roche Inc. | Growth hormone releasing factor analogs |
| US4689318A (en) * | 1985-08-29 | 1987-08-25 | The Salk Institute For Biological Studies | GRF analogs |
| IL86102A (en) * | 1987-05-11 | 1994-04-12 | Univ Tulane | Alkylated peptides that release growth hormone and their use |
-
1991
- 1991-04-30 EP EP19910909888 patent/EP0527914A4/en not_active Withdrawn
- 1991-04-30 JP JP3509839A patent/JPH06502618A/ja active Pending
- 1991-04-30 CA CA002082059A patent/CA2082059A1/fr not_active Abandoned
- 1991-04-30 AU AU78822/91A patent/AU651976B2/en not_active Expired - Fee Related
- 1991-04-30 WO PCT/US1991/003053 patent/WO1991016923A1/fr not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1996392A (en) * | 1991-05-15 | 1992-12-30 | Salk Institute For Biological Studies, The | Grf analogs xi |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991016923A1 (fr) | 1991-11-14 |
| AU7882291A (en) | 1991-11-27 |
| EP0527914A4 (en) | 1993-08-11 |
| EP0527914A1 (fr) | 1993-02-24 |
| CA2082059A1 (fr) | 1991-11-05 |
| JPH06502618A (ja) | 1994-03-24 |
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