EP0527914A4 - Novel synthetic grf analogs - Google Patents

Novel synthetic grf analogs

Info

Publication number
EP0527914A4
EP0527914A4 EP19910909888 EP91909888A EP0527914A4 EP 0527914 A4 EP0527914 A4 EP 0527914A4 EP 19910909888 EP19910909888 EP 19910909888 EP 91909888 A EP91909888 A EP 91909888A EP 0527914 A4 EP0527914 A4 EP 0527914A4
Authority
EP
European Patent Office
Prior art keywords
novel synthetic
grf analogs
synthetic grf
analogs
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910909888
Other languages
English (en)
Other versions
EP0527914A1 (fr
Inventor
David H. Coy
William Murphy
Simon J. Hocart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
Original Assignee
Tulane University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tulane University filed Critical Tulane University
Publication of EP0527914A1 publication Critical patent/EP0527914A1/fr
Publication of EP0527914A4 publication Critical patent/EP0527914A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Luminescent Compositions (AREA)
EP19910909888 1990-05-04 1991-04-30 Novel synthetic grf analogs Withdrawn EP0527914A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51905490A 1990-05-04 1990-05-04
US519054 1990-05-04

Publications (2)

Publication Number Publication Date
EP0527914A1 EP0527914A1 (fr) 1993-02-24
EP0527914A4 true EP0527914A4 (en) 1993-08-11

Family

ID=24066591

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19910909888 Withdrawn EP0527914A4 (en) 1990-05-04 1991-04-30 Novel synthetic grf analogs

Country Status (5)

Country Link
EP (1) EP0527914A4 (fr)
JP (1) JPH06502618A (fr)
AU (1) AU651976B2 (fr)
CA (1) CA2082059A1 (fr)
WO (1) WO1991016923A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262519A (en) * 1991-05-15 1993-11-16 The Salk Institute For Biological Studies GRF analogs XI
WO1994011397A1 (fr) * 1992-11-13 1994-05-26 The Administrators Of The Tulane Educational Fund Agonistes de somatostatine
WO1994011396A1 (fr) * 1992-11-13 1994-05-26 The Administrators Of The Tulane Educational Fund Agonistes de l'hormone de liberation de l'hormone de croissance
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
US6184208B1 (en) 1994-06-29 2001-02-06 Immunotech Developments Inc. Peptide, a method for its preparation and a pharmaceutical composition containing the peptide
CA2158782C (fr) * 1994-09-23 2010-01-12 Pierrette Gaudreau Marqueur pour recepteurs de facteurs liberant des hormones de croissance
CA2218173A1 (fr) * 1995-04-14 1996-10-17 The Administrators Of The Tulane Educational Fund Analogues du facteur liberant l'hormone de croissance
US6458764B1 (en) * 1995-05-26 2002-10-01 Theratechnologies Inc. GRF analogs with increased biological potency
US5942489A (en) * 1996-05-03 1999-08-24 The Administrators Of The Tulane Educational Fund HGH-RH(1-29)NH2 analogues having antagonistic activity
US6057422A (en) * 1998-11-25 2000-05-02 The Administrators Of The Tulane Educational Fund Antagonistic analogs of GH-RH inhibiting IGF-I and -II
US8691942B2 (en) 2008-03-28 2014-04-08 University Of Miami N- and C- terminal substituted antagonistic analogs of GH-RH
CA2718146C (fr) * 2008-03-28 2016-09-20 The University Of Miami Nouveaux analogues antagonistes substitues n- et c-terminaux de gh-rh
KR101642363B1 (ko) 2008-06-12 2016-07-25 입센 바이오이노베이션 리미티드 신경내분비계 질환의 억제
CN102083451A (zh) 2008-06-12 2011-06-01 赛恩泰新公司 癌症的抑制
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
EP3920961A4 (fr) 2019-02-08 2022-12-14 United States Government as represented by the Department of Veterans Affairs Antagonistes d'hormone de libération d'hormone de croissance et leurs utilisations

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0314866A2 (fr) * 1987-05-11 1989-05-10 The Administrators of The Tulane University Educational Fund Peptides alkylés libérant les hormones et méthode pour traiter les mammifères

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649131A (en) * 1984-09-24 1987-03-10 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
US4689318A (en) * 1985-08-29 1987-08-25 The Salk Institute For Biological Studies GRF analogs
US5262519A (en) * 1991-05-15 1993-11-16 The Salk Institute For Biological Studies GRF analogs XI

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0314866A2 (fr) * 1987-05-11 1989-05-10 The Administrators of The Tulane University Educational Fund Peptides alkylés libérant les hormones et méthode pour traiter les mammifères

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9116923A1 *
Therapeutic agents produced by genetic engineering, "Quo Vadis?" Symposium, Sanofi Group, May 29-30, 1985 Toulouse-Labège, France *

Also Published As

Publication number Publication date
EP0527914A1 (fr) 1993-02-24
WO1991016923A1 (fr) 1991-11-14
AU7882291A (en) 1991-11-27
CA2082059A1 (fr) 1991-11-05
AU651976B2 (en) 1994-08-11
JPH06502618A (ja) 1994-03-24

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19921204

AK Designated contracting states

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Ipc: C07K 7/10

A4 Supplementary search report drawn up and despatched

Effective date: 19930618

AK Designated contracting states

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17Q First examination report despatched

Effective date: 19950613

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19951027