AU6492600A - Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs - Google Patents

Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs

Info

Publication number
AU6492600A
AU6492600A AU64926/00A AU6492600A AU6492600A AU 6492600 A AU6492600 A AU 6492600A AU 64926/00 A AU64926/00 A AU 64926/00A AU 6492600 A AU6492600 A AU 6492600A AU 6492600 A AU6492600 A AU 6492600A
Authority
AU
Australia
Prior art keywords
prodrugs
camptothecin
derivatives
methods
treating cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU64926/00A
Other languages
English (en)
Inventor
Zhisong Cao
Beppino C. Giovanella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stehlin Foundation for Cancer Research
Original Assignee
Stehlin Foundation for Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/365,632 external-priority patent/US6096336A/en
Application filed by Stehlin Foundation for Cancer Research filed Critical Stehlin Foundation for Cancer Research
Publication of AU6492600A publication Critical patent/AU6492600A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
AU64926/00A 1999-08-03 2000-07-25 Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs Abandoned AU6492600A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09365632 1999-08-03
US09/365,632 US6096336A (en) 1996-01-30 1999-08-03 Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
US09499684 2000-02-08
US09/499,684 US6352996B1 (en) 1999-08-03 2000-02-08 Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
PCT/US2000/020136 WO2001008663A2 (en) 1999-08-03 2000-07-25 Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs

Publications (1)

Publication Number Publication Date
AU6492600A true AU6492600A (en) 2001-02-19

Family

ID=43706143

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64926/00A Abandoned AU6492600A (en) 1999-08-03 2000-07-25 Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs

Country Status (6)

Country Link
US (1) US6352996B1 (enExample)
EP (1) EP1200068A2 (enExample)
JP (1) JP2003528808A (enExample)
AU (1) AU6492600A (enExample)
CA (1) CA2379660A1 (enExample)
WO (1) WO2001008663A2 (enExample)

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US9186322B2 (en) * 2002-08-02 2015-11-17 Insmed Incorporated Platinum aggregates and process for producing the same
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AU2003302986A1 (en) * 2002-12-13 2004-07-09 Aurelium Biopharma Inc. Nucleophosmin directed diagnostics and therapeutics for multidrug resistant neoplastic disease
WO2005062058A1 (en) * 2002-12-13 2005-07-07 Aurelium Biopharma Inc. Vimentin directed diagnostics and therapeutics for multidrug resistant neoplastic disease
US7226748B2 (en) * 2003-01-03 2007-06-05 Aurelium Biopharma, Inc. HSC70 directed diagnostics and therapeutics for multidrug resistant neoplastic disease
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US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US7572803B2 (en) * 2007-10-25 2009-08-11 The Christus Stehlin Foundation For Cancer Research Hydrated crystalline esters of camptothecin
US8067432B2 (en) * 2008-03-31 2011-11-29 University Of Kentucky Research Foundation Liposomal, ring-opened camptothecins with prolonged, site-specific delivery of active drug to solid tumors
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WO2013177226A1 (en) 2012-05-21 2013-11-28 Insmed Incorporated Systems for treating pulmonary infections
RU2682249C2 (ru) * 2012-05-31 2019-03-18 Терумо Кабусики Кайся рН-ЧУВСТВИТЕЛЬНЫЙ НОСИТЕЛЬ И СПОСОБ ЕГО ПОЛУЧЕНИЯ, И рН-ЧУВСТВИТЕЛЬНОЕ ЛЕКАРСТВЕННОЕ СРЕДСТВО, И рН-ЧУВСТВИТЕЛЬНАЯ ЛЕКАРСТВЕННАЯ КОМПОЗИЦИЯ, ГДЕ КАЖДОЕ ИЗ НИХ СОДЕРЖИТ НОСИТЕЛЬ, И СПОСОБ КУЛЬТИВИРОВАНИЯ С ИХ ПРИМЕНЕНИЕМ
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WO2014081887A1 (en) 2012-11-20 2014-05-30 Spectrum Pharmaceuticals Improved method for the preparation of liposome encapsulated vincristine for therapeutic use
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ES2755941T3 (es) 2014-05-15 2020-04-24 Insmed Inc Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas
TWI678213B (zh) 2015-07-22 2019-12-01 美商史倍壯製藥公司 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物
EP3426301A4 (en) * 2016-03-08 2019-11-06 Los Gatos Pharmaceuticals, Inc. VERBUNDNANOPARTICLES AND USES THEREOF
WO2019191627A1 (en) 2018-03-30 2019-10-03 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
WO2021172359A1 (ja) * 2020-02-25 2021-09-02 大日本住友製薬株式会社 Ｃｄｋ９阻害剤プロドラッグ及びそれを内封するリポソーム
TW202323251A (zh) * 2021-08-23 2023-06-16 日商住友製藥股份有限公司 自我分解型cdk9抑制劑前藥及內封其之脂質體

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Also Published As

Publication number Publication date
WO2001008663A3 (en) 2001-07-26
EP1200068A2 (en) 2002-05-02
WO2001008663A2 (en) 2001-02-08
CA2379660A1 (en) 2001-02-08
US6352996B1 (en) 2002-03-05
JP2003528808A (ja) 2003-09-30

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